Neuroblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating samotolisib in pediatric patients with relapsed or refractory tumors harboring TSC or PI3K/mTOR mut…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: A Study Of Naxitamab , Granulocyte Macrophage Colony Stimulating Factor For Patients With Relapsed /Refractory , Soft Tissue or Anti GD2 Immunotherapy Refractory Neuroblastoma [Phase 2]
Phase 2 study of naxitamab in combination with GM-CSF for relapsed/refractory neuroblastoma and anti-GD2 immunotherapy-refractory soft tissu…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Adding Of Naxitamb In Induction Therapy For High Risk Neuroblastoma
Clinical trial update indicates naxitamab is being added to induction therapy for high-risk neuroblastoma, with the trial currently recruiti…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: 68Ga-DOTATATE Neuroblastoma Imaging Pilot [Phase 2]
A Phase 2 pilot study is evaluating 68Ga-DOTATATE PET imaging for neuroblastoma, and the trial is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL) [Phase 2]
A Phase 2 trial evaluating a multi-agent regimen of dinutuximab, GM-CSF, isotretinoin, irinotecan, and temozolomide after intensive therapy …
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)
A clinical trial is currently recruiting to investigate neurocognition in congenital central hypoventilation syndrome (CCHS) and related CCH…
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CLINICAL_TRIALS withdrawal · 2024-08-07Clinical Trial Update: Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastoma [Phase 2]
A Phase 2 trial evaluating defibrotide prophylaxis to prevent transplant-associated thrombotic microangiopathy in neuroblastoma patients has…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: A Trial Using Molecular-Guided Therapy in Patients With Refractory or Recurrent Neuroblastoma
A completed clinical trial investigated molecular-guided therapy in patients with refractory or relapsed neuroblastoma.
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Trial of Tolcapone With Oxaliplatin for Neuroblastoma [Phase 1]
This update indicates that a Phase 1 trial of tolcapone in combination with oxaliplatin for neuroblastoma has been terminated.
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CLINICAL_TRIALS withdrawal · 2024-08-05Clinical Trial Update: PediCARE Health Equity Intervention in High-Risk Neuroblastoma [NA]
The PediCARE health equity trial for high-risk neuroblastoma has been withdrawn. The study was sponsored by Dana-Farber Cancer Institute.
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: Identification of New Gene Spliceosomes in Neuroblastoma
A clinical trial investigating new gene spliceosomes in neuroblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma
This document outlines an expanded access/compassionate use protocol for 131I-MIBG therapy. It targets patients with refractory neuroblastom…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Psychosocial Situation of Children With Rare Solid Abdominal Tumors and Their Families
This update reports the completion of a clinical trial examining the psychosocial experiences of children with rare solid abdominal tumors a…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Nutritional Status in Neuroblastoma in Sao Paolo, Brazil
This clinical trial update reports on a completed study examining nutritional status in patients with neuroblastoma in São Paulo, Brazil, sp…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification
This clinical trial update reports ongoing recruitment for a study stratifying risk factors in abdominal neuroblastoma patients undergoing l…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors [Phase 1]
Phase I trial update of T cells engineered to express an anti-GD2 chimeric antigen receptor in children and young adults with GD2-positive s…
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in Children [Phase 2]
Phase 2 trial evaluating bevacizumab with temozolomide with or without irinotecan for pediatric neuroblastoma; the study is currently active…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Metronomic Treatment in Children and Adolescents With Recurrent or Progressive High Risk Neuroblastoma [Phase 2]
Phase 2 clinical trial update on metronomic treatment for children and adolescents with recurrent or progressive high-risk neuroblastoma. Th…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) [Phase 2]
Phase 2 pediatric trial of Genistein for various cancers was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Molecular-Guided Therapy for Relapsed and Refractory Childhood Cancer [NA]
A completed pediatric trial evaluated molecular-guided therapy for relapsed and refractory cancers, including neuroblastoma and medulloblast…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Study of Difluoromethylornithine (DFMO) in Combination With Bortezomib for Relapsed or Refractory Neuroblastoma [Phase 1, Phase 2]
Phase 1/2 study evaluating the combination of difluoromethylornithine (DFMO) with bortezomib in relapsed or refractory neuroblastoma has com…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
A pediatric MATCH phase 2 trial assessed olaparib in children with relapsed or refractory advanced solid tumors or non-Hodgkin lymphoma carr…
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CLINICAL_TRIALS trial_result · 2024-04-24Clinical Trial Update: Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating palbociclib in relapsed or refractory pediatric tumors with activating alterations in cell cycle ge…
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CLINICAL_TRIALS trial_result · 2024-04-22Clinical Trial Update: Safety Study of Dinutuximab Combined With Immunotherapy to Treat Neuroblastoma [Phase 2]
Phase 2 safety study evaluating dinutuximab combined with immunotherapy for neuroblastoma has completed.
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Molecular-Guided Therapy for Childhood Cancer [NA]
A completed clinical trial evaluating molecular-guided therapy for several childhood cancers, with results posted in April 2024.