Neuroblastoma
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Chromosomes in Samples From Younger Patients With Neuroblastoma
The update reports a completed trial investigating chromosomal analyses in samples from younger neuroblastoma patients. It is sponsored by t…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Study of DNA in Blood Samples From Patients With Neuroblastoma
A completed clinical trial investigating DNA in blood samples from patients with neuroblastoma, sponsored by the Children's Oncology Group.
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Gene Expression in Samples From Younger Patients With Neuroblastoma
A completed clinical trial update studying gene expression in samples from younger patients with neuroblastoma.
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CLINICAL_TRIALS research · 2016-05-18Clinical Trial Update: Study of Specimens From Young Patients With Neuroblastoma
Clinical trial update indicating completion of a study that collects specimens from young patients with neuroblastoma. The study spans multi…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Gene Expression in Predicting Outcome in Samples From Patients With High-Risk Neuroblastoma
This completed trial from the Children's Oncology Group investigates whether gene expression patterns in tumor samples can predict outcomes …
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Protein Expression in Human Neuroblastoma Tumor Samples
The study analyzes protein expression in neuroblastoma tumor samples from pediatric patients. It updates on biomarker findings derived from …
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CLINICAL_TRIALS research · 2016-04-15Clinical Trial Update: Biomarkers in Samples From Young Patients With Neuroblastoma
Clinical Trial Update reporting biomarkers analyzed in samples from young patients with neuroblastoma. The trial has completed.
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB [Phase 1, Phase 2]
Phase I dose-finding and safety study of LDE225 (sonidegib) in children with recurrent or refractory medulloblastoma, with a Phase II portio…
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006) [Phase 1]
Phase 1 trial of robatumumab (SCH 717454, MK-7454) in combination with different regimens in pediatric participants with advanced solid tumo…
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CLINICAL_TRIALS trial_result · 2016-02-09Clinical Trial Update: MLN8237 to Treat Children With Relapsed/Refractory Solid Tumors [Phase 1]
Phase 1 trial update showing completion of MLN8237 (alisertib) in children with relapsed/refractory solid tumors, including neuroblastoma.
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CLINICAL_TRIALS trial_result · 2016-02-04Clinical Trial Update: A Phase II Study of Intensity Modulated Radiation Therapy (IMRT) in High Risk Abdominal Neuroblastoma [Phase 2]
A Phase II study evaluating intensity-modulated radiation therapy (IMRT) in high-risk abdominal neuroblastoma was terminated, with results p…
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Studies of Temozolomide in Combination With Topotecan in Refractory and Relapsed Paediatric Solid Tumours [Phase 2]
This Phase 2 trial update notes the completion of studies evaluating temozolomide in combination with topotecan for refractory and relapsed …
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients [Phase 1]
Phase 1 safety study of a recombinant vaccinia virus (JX-594/Pexa-Vec) for refractory pediatric solid tumors. The trial has completed and en…
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CLINICAL_TRIALS trial_result · 2016-01-07Clinical Trial Update: Traumeel® S in Preventing and Treating Mucositis in Young Patients Undergoing Stem Cell Transplantation [NA]
This clinical trial update reports completion of a study evaluating Traumeel S for prevention and treatment of mucositis in pediatric stem c…
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CLINICAL_TRIALS withdrawal · 2015-12-03Clinical Trial Update: Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor [Phase 2]
A Phase 2 pediatric trial evaluating chemotherapy followed by peripheral stem cell transplantation for newly diagnosed brain tumors has been…
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CLINICAL_TRIALS withdrawal · 2015-11-26Clinical Trial Update: Efficacy and Safety of Ultratrace™ Iobenguane I 131 in Neuroblastoma [Phase 2]
A Phase 2 clinical trial evaluating Ultratrace Iobenguane I-131 for Neuroblastoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors [Phase 2]
Arsenic trioxide was studied in a Phase 2 trial for children with advanced neuroblastoma and other childhood solid tumors; results have been…
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CLINICAL_TRIALS trial_result · 2015-11-24Clinical Trial Update: Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma [Phase 1]
This clinical-trial update reports the completion of a Phase 1 study evaluating a combination of vorinostat and isotretinoin in patients wit…
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CLINICAL_TRIALS withdrawal · 2015-10-16Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed or Refractory High-Risk NBL. [Phase 2]
The Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation for relapsed or refractory high-risk neuroblastoma has been …
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Iodine I 131 Monoclonal Antibody 3F8 and Bevacizumab in Treating Patients With Relapsed or Refractory Neuroblastoma [Phase 1]
A completed Phase 1 study evaluating the combination of 3F8 (Iodine-131 labeled monoclonal antibody) and bevacizumab in relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2015-09-23Clinical Trial Update: ch14.18 Pharmacokinetic Study in High-risk Neuroblastoma [Phase 1, Phase 2]
This clinical trial evaluated the pharmacokinetics of ch14.18 (dinutuximab) in high-risk neuroblastoma in Phase 1/Phase 2. The study is comp…
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: High-Dose 131I-MIBG Therapy Combined With Vincristine and Five Days of Irinotecan for Resistant/Relapsed Neuroblastoma [Phase 1]
Phase 1 trial evaluating high-dose 131I-MIBG therapy combined with vincristine and five days of irinotecan for resistant/relapsed neuroblast…
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides [Phase 1]
A Phase 1 clinical trial of Racotumomab in pediatric tumors expressing N-glycolylated gangliosides has completed enrollment and reported res…
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CLINICAL_TRIALS research · 2015-07-16Clinical Trial Update: Combination Chemotherapy Followed by Stem Cell Transplant and Isotretinoin in Treating Young Patients With High-Risk Neuroblastoma [NA]
A clinical trial update describes evaluating a treatment sequence of combination chemotherapy followed by stem cell transplant and isotretin…
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CLINICAL_TRIALS research · 2015-06-25Clinical Trial Update: Understanding Patient Perspectives on the Risks of Ionizing Radiation Used for Medical Imaging
Completed MSK clinical trial examining patient perspectives on the risks of ionizing radiation from medical imaging across several cancer ty…