Nephrolithiasis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2017-08-09Clinical Trial Update: The Alternating Bidirectional Versus The Standard Approach During Shock Wave Lithotripsy For Renal And Upper Lumbar Ureteric Stones [NA]
This clinical trial update compares alternating bidirectional versus standard approaches during shock wave lithotripsy for kidney and upper …
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CLINICAL_TRIALS research · 2017-06-07Clinical Trial Update: Prone Versus Prone-Flexed Position For Percutaneous Nephrolithotomy (PCNL) [NA]
A clinical trial update compares prone versus prone-flexed positioning during percutaneous nephrolithotomy (PCNL). The trial status is unkno…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Conventional Antibiotic Prophylaxis Versus Add-On 5 Days Levofloxacin Before Percutaneous Nephrolithotomy [NA]
A clinical trial comparing conventional antibiotic prophylaxis to an add-on five-day levofloxacin regimen before percutaneous nephrolithotom…
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CLINICAL_TRIALS research · 2017-04-28Clinical Trial Update: Over 2000 Epidural Anesthesias for Percutaneous Nephrolithotomy - a Retrospective Analysis
A retrospective analysis of over 2,000 epidural anesthesia procedures used during percutaneous nephrolithotomy, detailing practice patterns …
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CLINICAL_TRIALS research · 2017-04-13Clinical Trial Update: Comparison of Multiple-, Single- and Zero-dose of Ciprofloxacin Prophylaxis in Retrograde Intrarenal Surgery [NA]
A clinical trial evaluating different ciprofloxacin prophylaxis dosing regimens (multiple, single, or no dose) in retrograde intrarenal surg…
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CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: Fluid Intake Application to Reduce Kidney Stone Risks
A completed clinical trial evaluated whether higher fluid intake reduces the risk of nephrolithiasis (kidney stones). The results may inform…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Can a Spot Urine Replace or Improve 24 Hour Urine Collections in Kidney Stone Patients
A terminated clinical trial update evaluating whether spot urine tests can replace or improve 24-hour urine collections in nephrolithiasis p…
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CLINICAL_TRIALS withdrawal · 2017-02-17Clinical Trial Update: Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy [Phase 3]
A Phase 3 trial comparing silodosin versus tamsulosin for stone clearance after extracorporeal shock wave lithotripsy has been withdrawn.
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CLINICAL_TRIALS research · 2017-02-13Clinical Trial Update: The Influence of SMP on Renal Pelvic Pressure In Vivo [NA]
Clinical trial update examining the influence of SMP on renal pelvic pressure in vivo in nephrolithiasis; phase and status details are not p…
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days [Phase 2]
Phase 2 trial evaluating ALLN-177 for reducing urinary oxalate in patients with secondary hyperoxaluria and nephrolithiasis over 28 days; th…
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CLINICAL_TRIALS withdrawal · 2017-01-09Clinical Trial Update: The Effect of Vitamin D on Urinary Calcium Excretion in Kidney Stone Formers With High Urinary Calcium [Phase 2, Phase 3]
Brigham and Women's Hospital's Phase 2/3 trial investigating the effect of vitamin D on urinary calcium excretion in kidney stone formers ha…
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CLINICAL_TRIALS withdrawal · 2017-01-05Clinical Trial Update: A Trial of Pyridoxamine to Lower Urine Oxalate in Subjects With Stone Disease or Hyperoxaluria [Phase 2]
A Phase 2 trial investigating pyridoxamine to reduce urine oxalate in people with nephrolithiasis or hyperoxaluria has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: FloSeal Tubeless Exit Versus Cope Loop Nephrostomy Versus Fascial Stitch Following Percutaneous Nephrolithotripsy [NA]
A clinical trial comparing FloSeal tubeless exit, Cope loop nephrostomy, and fascial stitch after percutaneous nephrolithotripsy has complet…
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CLINICAL_TRIALS research · 2016-10-28Clinical Trial Update: Assessment of Flexible Ureteroscopy Residual Fragments
Clinical trial update on assessing residual fragments after flexible ureteroscopy for nephrolithiasis; no current status information is prov…
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients [NA]
The trial completed and posted results evaluating the efficacy of tamsulosin for treating ureteral stones in emergency department patients.
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: The Comparison of Low Thoracic Paravertebral Block Versus Peritubal Infiltration [Phase 4]
Phase 4 clinical trial comparing low thoracic paravertebral block with peritubal infiltration for analgesia in patients undergoing Percutane…
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: Segmental Epidural Anesthesia (SEA) V/S General Anesthesia for PCNL [Phase 4]
A Phase 4 trial comparing segmental epidural anesthesia to general anesthesia for percutaneous nephrolithotomy has completed, evaluating suc…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: Comparison of Different Analgesia Drug Regimens for Pain Control During ESWL for Renal Stones [NA]
This completed trial compared different analgesia regimens for pain control during extracorporeal shock wave lithotripsy (ESWL) in patients …
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria [Phase 2]
Phase 2 clinical trial evaluating ALLN-177 to reduce urinary oxalate excretion in adults with hyperoxaluria and kidney stones has completed …
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Escalating, Constant and Reduction Energy Output in SWL for Renal Stones [NA]
The ClinicalTrials.gov entry indicates the trial evaluating escalating, constant, and reduction energy outputs in shock wave lithotripsy for…
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CLINICAL_TRIALS trial_result · 2016-03-30Clinical Trial Update: Use of Tolvaptan to Reduce Urinary Supersaturation: a Pilot Proof of Principle Study [Phase 1]
Phase 1 pilot study evaluating whether tolvaptan can reduce urinary supersaturation in nephrolithiasis due to calcium oxalate or calcium pho…
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Flexible Ureteroscopy Versus ESWL in the Management of Lower Calyceal Stones [NA]
A completed clinical trial comparing flexible ureteroscopy to extracorporeal shock wave lithotripsy for managing lower calyceal stones.
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CLINICAL_TRIALS withdrawal · 2015-10-12Clinical Trial Update: Potassium Citrate Supplementation vs. Dietary Counseling [Phase 2]
A Phase 2 clinical trial evaluating potassium citrate supplementation versus dietary counseling for nephrolithiasis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-08-11Clinical Trial Update: Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones [NA]
A completed clinical trial comparing laser versus ultrasonic lithotripsy during percutaneous nephrolithotomy for staghorn stones.
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CLINICAL_TRIALS research · 2015-07-14Clinical Trial Update: Aqueduct Irrigation System Clinical Protocol: Medical Device Investigational Plan [NA]
This document provides an update to the clinical protocol for Flowmed's Aqueduct Irrigation System medical device; no study results are repo…