Necrotizing Enterocolitis
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Effects of Implementation of a Care Bundle on Rates of NEC and Own Mother's Milk Feeding in the East Midlands
A completed clinical trial evaluated the impact of implementing a care bundle on rates of necrotizing enterocolitis in neonates and on exclu…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Use of Faecal Calprotectin to Predict Enteropathy of the Preterm Neonates [NA]
A completed clinical trial evaluated whether fecal calprotectin can predict enteropathy, including necrotizing enterocolitis, in preterm neo…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Amniotic Fluid & the Preterm Gut
Recruitment is ongoing for a study examining amniotic fluid and the preterm gut. The study targets several associated neonatal conditions, i…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: The Correlation Between Red Cell Transfusion and Complications of Prematurity
This clinical trial examines whether red blood cell transfusions are associated with complications of prematurity, including retinopathy of …
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants
Completed clinical trial evaluating platelet activation markers to identify late-onset sepsis in preterm infants, including culture-negative…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Early Predictors of Necrotizing Enterocolitis in Neonates
A clinical trial at Nationwide Children's Hospital is investigating early predictors of necrotizing enterocolitis in neonates, with recruitm…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: A Genome-Wide Association Study for Neonatal Diseases
This clinical trial update reports a genome-wide association study investigating neonatal diseases, including necrotizing enterocolitis, whi…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Application of Transcriptome Sequencing Combined With Family-Based Whole Genome Sequencing in Improving Precise Diagnosis of Critically Ill Newborns in Northeast China
This clinical trial investigates using transcriptome sequencing combined with family-based whole genome sequencing to improve precise diagno…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: The Intestinal Innate Immune System in Newborns. Development and Inflammation in Health and Disease
An ongoing clinical study evaluating how the intestinal innate immune system develops in newborns and how inflammation relates to health and…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Do Probiotics Reduce The Risk Of Severe Necrotising Enterocolitis (NEC) In Infants Born Before 32 Weeks Gestation?
An Imperial College London trial is evaluating whether probiotic therapy can reduce the risk of severe necrotizing enterocolitis in infants …
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Milk Temperature Control and Necrotizing Enterocolitis Risk in Extremely Preterm Infants [NA]
Clinical trial evaluating whether milk temperature control influences necrotizing enterocolitis risk in extremely preterm infants. The study…
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Neutrophil Extracellular Trap Formation in Newborn Infants at Risk for Inflammatory Syndromes
A University of Utah-sponsored clinical trial investigates neutrophil extracellular trap formation in newborns at risk for inflammatory synd…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Non-Invasive Prediction of Necrotizing Enterocolitis in Preterm Neonates with Feeding Intolerance Using Fecal Lipocalin-2 and Electrical Cardiometry
Ain Shams University is conducting a trial to explore non-invasive prediction of necrotizing enterocolitis in preterm neonates with feeding …
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Enrichment of Human Milk With Human and Bovine Milk-based Fortifiers for Very Preterm Infants: a Meta-analysis
This document reports a meta-analysis on enriching human milk with human and bovine milk-based fortifiers for very preterm infants, examinin…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Antibiotic Exposure on Gut Microbiota and Motility Establishment in Newborns
An ongoing clinical trial sponsored by The First Hospital of Jilin University evaluates how antibiotic exposure affects gut microbiota devel…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Alteration of Stool Microbiota in Preterm Infants With Anemia
This completed clinical trial studied alteration of stool microbiota in preterm infants with anemia.
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants [Phase 3]
Phase 3 trial to evaluate whether multi-strain probiotics can prevent necrotizing enterocolitis in very preterm infants; recruitment has not…
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Safety and PK-PD Study of Oral L-CIT in Preterm Infants with BPD±PH and NEC [NA]
Clinical trial update describing a safety and pharmacokinetic/pharmacodynamic study of oral L-CIT in preterm infants with bronchopulmonary d…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: The Effect of Umbilical Vein Catheterization on Splanchnic Oxygenation in Preterm Infants
A completed clinical trial assessing whether umbilical vein catheterization affects splanchnic oxygenation in preterm infants, focusing on f…
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CLINICAL_TRIALS research · 2025-01-03Clinical Trial Update: Necrotizing Enterocolitis and Bowel Perforation in Very Preterm Infants - Long-term Follow up
This is a long-term follow-up update for a clinical trial investigating necrotizing enterocolitis and bowel perforation in very preterm infa…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Primary Anastomosis Versus Enterostomy in the Surgical Treatment of Necrotising Enterocolitis [NA]
Clinical trial comparing primary anastomosis versus enterostomy for surgical treatment of necrotizing enterocolitis; currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Calprotectin Levels in Necrotizing Enterocolitis
A completed clinical trial evaluating calprotectin levels in neonatal necrotizing enterocolitis.
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: PrePhage - Faecal Bacteriophage Transfer for Enhanced Gastrointestinal Tract Maturation in Preterm Infants [EARLY_Phase 1]
An early Phase 1 trial investigating PrePhage, a faecal bacteriophage transfer, to promote gastrointestinal tract maturation in preterm infa…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Identification of Clostridium Butyricum and Clostridium Neonatal in the Digestive Microbiota of Premature Infants Before 34 Weeks and Developing or Not Ulcerative Necrotizing Enterocolitis (NEC) During Hospitalization
This clinical trial investigates whether colonization by Clostridium butyricum and Clostridium neonatale in the gut of very premature infant…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: CEUS Evaluation of Bowel Perfusion in Necrotizing Enterocolitis [Phase 3]
Phase 3 trial evaluating CEUS for bowel perfusion in necrotizing enterocolitis in newborns was terminated. Results have been posted.