Nasopharyngeal Carcinoma
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Patients With Stage III-IVa Nasopharyngeal Carcinoma With or Without a Mobile Medical Platform Full-course Nutritional Intervention [NA]
This clinical trial update reports completion of a study evaluating a full-course nutritional intervention delivered via a mobile medical pl…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Cadonilimab (PD-1/CTLA-4 Bispecific Blockade) and Chemoradiotherapy in Nasopharyngeal Carcinoma (GEMSTONE) [Phase 3]
Phase 3 GEMSTONE study of cadonilimab (PD-1/CTLA-4 bispecific) in combination with chemoradiotherapy for nasopharyngeal carcinoma is current…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: NPC - AXEL Study : Axitinib-Avelumab [Phase 2]
Phase 2 trial evaluating the axitinib-avelumab combination in recurrent or metastatic nasopharyngeal carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-12-31Clinical Trial Update: Neoadjuvant Chemotherapy and Low-dose Radiotherapy Sequential Concurrent Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma [NA]
This clinical trial update reports the completion of a study evaluating neoadjuvant chemotherapy and low-dose radiotherapy followed by seque…
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CLINICAL_TRIALS trial_result · 2024-12-30Clinical Trial Update: Irinotecan Liposomes in Combination With Nituzumab for the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma After Failure of First-Line or Higher Immunotherapy [Phase 2]
A Phase 2 clinical trial evaluating the combination of irinotecan liposomes with nituzumab for recurrent/metastatic nasopharyngeal carcinoma…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma [Phase 1]
Phase 1 trial testing EBV-specific cytotoxic T cells in relapsed EBV-positive lymphomas has completed, assessing safety and preliminary acti…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Toripalimab and Anlotinib Combination Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma After Failure of at Least One Line of Platinum-Based Chemotherapy (TORAL) [Phase 2]
TORAL is a Phase 2 trial evaluating toripalimab in combination with anlotinib for recurrent or metastatic nasopharyngeal carcinoma after pla…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Tabelecleucel in Combination With Pembrolizumab in Subjects With Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC) [Phase 1, Phase 2]
A Phase 1/2 trial of tabelecleucel in combination with pembrolizumab for Epstein-Barr virus-associated nasopharyngeal carcinoma was terminat…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Compassionate Use of Asparaginase and Pembrolizumab Combination Theaapy for Nasopharyngeal Carcinoma [NA]
A completed compassionate-use study investigates a combination of asparaginase and pembrolizumab for nasopharyngeal carcinoma.
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports termination of the INBRX-105 in combination with pembrolizumab across multiple solid tumors, including hea…
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: A Study of TQB2450 in Combination With Intensity-modulated Radiotherapy in Patients With Inoperable Locally Recurrent Nasopharyngeal Carcinoma [Phase 2]
Phase 2 study evaluating TQB2450 in combination with intensity-modulated radiotherapy for patients with inoperable locally recurrent nasopha…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: Long-term Outcomes of Early-stage Nasopharyngeal Carcinoma Patients Treated with Radiotherapy Alone
The update discusses long-term outcomes of early-stage nasopharyngeal carcinoma patients treated with radiotherapy alone in a Taichung Veter…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer [Phase 3]
Phase 3 trial evaluating adding nivolumab to standard chemotherapy (cisplatin or carboplatin with gemcitabine) for recurrent or metastatic n…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Prognostic Utility of the Imaging and Biological Signatures in Nasopharyngeal Carcinoma [NA]
This clinical trial update reports on a completed study evaluating the prognostic utility of imaging and biological signatures in nasopharyn…
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Hearing Impairment of Nasopharyngeal Carcinoma
A completed clinical trial studied hearing impairment in patients with nasopharyngeal carcinoma.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) [Phase 1]
This update reports the completion of a Phase 1 study (DUET-3) evaluating XmAb23104 in patients with selected advanced solid tumors.
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: The Effect of GM-CSF to Preventing Oral Mucositis for Patients With Nasopharyngeal Carcinoma Receiving Radiotherapy [Phase 2]
This Phase 2 trial, sponsored by Sun Yat-sen University, is evaluating whether GM-CSF can prevent oral mucositis in patients with nasopharyn…
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: Oral Enteral Nutrition in Delayed Onset Radiotherapy-related Swallowing Disorder in Nasopharyngeal Carcinoma [NA]
This clinical trial update notes the completion of a study evaluating oral enteral nutrition to manage delayed onset radiotherapy-related sw…
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: Nivolumab Plus Gemcitabine in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma-HN17-11 [Phase 2]
This Phase 2 trial evaluating nivolumab plus gemcitabine for recurrent or metastatic nasopharyngeal carcinoma has completed enrollment.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Nivolumab in Children and Adults With Nasopharyngeal Carcinoma [Phase 2]
Phase 2 study evaluating nivolumab in children and adults with nasopharyngeal carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: 18F-FMISO PET Guided Dose Escalation in Nasopharyngeal Carcinoma - a Feasibility and Planning Study [NA]
This clinical trial update reports completion of a feasibility and planning study that uses 18F-FMISO PET imaging to guide dose escalation i…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Bintrafusp Alfa in Previously Treated Patients With R/M Non-keratinizing NPC [Phase 2]
A Phase 2 study of bintrafusp alfa in previously treated patients with recurrent/metastatic nasopharyngeal carcinoma (non-keratinizing histo…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: A Phase 1 Study of BRG01 in Subjects With Relapsed/Metastatic Epstein-Barr Virus (EBV)-Positive Nasopharyngeal Carcinoma [Phase 1]
A Phase 1 study evaluating BRG01 in subjects with EBV-positive nasopharyngeal carcinoma has completed its Phase 1 portion.
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Radiation Plus Concurrent Nimotuzumab in Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma [Phase 2]
Phase 2 trial evaluating radiation with nimotuzumab in elderly patients with locoregionally advanced nasopharyngeal carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: Neoadjuvant and Adjuvant Tislelizumab for Nasopharyngeal Carcinoma [Phase 3]
Phase 3 trial update evaluating neoadjuvant and adjuvant tislelizumab in nasopharyngeal carcinoma is active/not recruiting.