Narcolepsy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-27Clinical Trial Results: A Study to Investigate the Effect of XYWAV on Sleepiness, Polysomnography, and Functional Outcomes in Participants With Idiopathic Hypersomnia or Narcolepsy [Phase 4]
Phase 4 trial investigating the effect of XYWAV on sleepiness, polysomnography, and functional outcomes in idiopathic hypersomnia and narcol…
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CLINICAL_TRIALS trial_result · 2026-06-30Clinical Trial Results: Narcolepsy Nightmare Study [NA]
Completed clinical trial results for Narcolepsy-related conditions; results posted.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: A Switch Study From High-Sodium Oxybate to Xywav to Evaluate Changes in Blood Pressure in Participants With Narcolepsy [Phase 4]
Phase 4 switch study evaluated blood pressure changes when narcolepsy patients moved from high-sodium oxybate (Xyrem) to Xywav, with results…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004) [Phase 1]
A Phase 1 study of MK-6552 in participants with narcolepsy has been terminated, with results posted on 2026-04-14.
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy [Phase 2]
A Phase 2 clinical trial to evaluate the efficacy and safety of the investigational drug E2086 in adults with narcolepsy; the study status i…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: A Study of HBS-201 (Pitolisant Delayed-release) [Phase 1]
A Phase 1 study evaluating HBS-201 (delayed-release pitolisant) for narcolepsy has completed.
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE) [Phase 3]
A Phase 3 study (ENCORE) evaluating the long-term efficacy and safety of AXS-12 (reboxetine) in narcolepsy with cataplexy and excessive dayt…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: An Open Label Study of FT218 in Subjects With Narcolepsy [Phase 3]
This open-label Phase 3 trial of FT218 in narcolepsy with cataplexy has completed, providing results on safety and efficacy in this populati…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: A Study to Investigate the Effect of XYWAV on Sleepiness, Polysomnography, and Functional Outcomes in Participants With Idiopathic Hypersomnia or Narcolepsy [Phase 4]
A Phase 4 study evaluating XYWAV for sleepiness, polysomnography metrics, and functional outcomes in idiopathic hypersomnia and narcolepsy h…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy [Phase 3]
Phase 3 trial of AXS-12 (Reboxetine) in narcolepsy with cataplexy has completed.
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of TS-091 in Patients with Narcolepsy [Phase 2]
Phase 2 study evaluating the safety and efficacy of TS-091 in patients with narcolepsy has completed.
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: A Study to Evaluate Safety, and Efficacy of SUVN-G3031 (Samelisant) in Patients With Narcolepsy With and Without Cataplexy [Phase 2]
Phase 2 study evaluating the safety and efficacy of Samelisant (SUVN-G3031) in narcolepsy patients with and without cataplexy has completed …
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: A Clinical Study of MK-6552 and Modafinil in Healthy Men (MK-6552-005) [Phase 1]
Phase 1 clinical trial assessing MK-6552 in combination with Modafinil in healthy men and individuals with narcolepsy; the study status is c…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: A Study to Collect Information of People With Narcolepsy in Spain
Takeda-sponsored observational study to collect information on people with narcolepsy in Spain has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: A Study of MK-6552 in Sleep Deprived Healthy Participants (MK-6552-003) [Phase 1]
This Phase 1 trial of MK-6552 (MK-6552-003) in sleep-deprived healthy participants and participants with narcolepsy has completed, with Merc…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: This is a Study to Determine the Effect of Multiple Doses of an Investigational Drug, Taken by Mouth, in People With Narcolepsy-cataplexy. Accepting Both Males and Females Ages of 18 Years to 55 Years. This Study Will be Conducted in the US and Will Require Approximately 13 Weeks Participation. [Phase 1]
A completed Phase 1 study evaluating the safety and tolerability of multiple oral doses of an investigational drug in adults with narcolepsy…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Narcolepsy Nightmare Study [NA]
A completed clinical trial update for the Narcolepsy Nightmare Study (NA) reported status as completed, with listed narcolepsy-related condi…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: An Interventional Safety Switch Study (Segue Study) of XYWAV in Narcolepsy [Phase 4]
Phase 4 interventional safety study in narcolepsy completed; results posted.
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: Awareness and Self-Compassion Enhancing Narcolepsy Treatment [NA]
A completed clinical trial investigating awareness and self-compassion as a treatment approach for narcolepsy (including with and without ca…
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CLINICAL_TRIALS trial_result · 2023-08-24Clinical Trial Update: Clinical Outcomes in Narcolepsy and Cataplexy: An Evaluation of Reboxetine Treatment (CONCERT) [Phase 2]
Phase 2 trial evaluating reboxetine for narcolepsy with cataplexy completed; results posted.
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CLINICAL_TRIALS trial_result · 2023-03-13Clinical Trial Update: An Open Label Study of NLS-2 (Mazindol Extended Release) in Subjects With Narcolepsy [Phase 2]
Phase 2 open-label trial of mazindol extended release (NLS-2) in narcolepsy with and without cataplexy completed.
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CLINICAL_TRIALS trial_result · 2022-08-12Clinical Trial Update: Four-week Study of the Safety and Efficacy of NLS-2 (Mazindol Extended Release) in the Treatment of Narcolepsy [Phase 2]
Phase 2 study evaluating safety and efficacy of mazindol extended release (NLS-2) for narcolepsy and related daytime sleepiness has complete…
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CLINICAL_TRIALS trial_result · 2022-03-22Clinical Trial Update: Once-Nightly Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy [Phase 3]
Phase 3 trial update for once-nightly sodium oxybate in narcolepsy assessing excessive daytime sleepiness and cataplexy completed with poste…
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CLINICAL_TRIALS trial_result · 2021-07-06Clinical Trial Update: A Study of the Safety and Effectiveness of ADX-N05 in the Treatment of Excessive Daytime Sleepiness [Phase 2]
Phase 2 study evaluating safety and effectiveness of ADX-N05 for excessive daytime sleepiness in narcolepsy completed.
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CLINICAL_TRIALS trial_result · 2021-01-13Clinical Trial Update: Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in Narcolepsy [Phase 2]
Phase 2 clinical trial evaluating the effects of JZP-110 on driving performance in adults with narcolepsy and excessive daytime sleepiness h…