Myocardial Infarction
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CLINICAL_TRIALS withdrawal · 2026-04-15Clinical Trial Update: STEMI Cool Pilot Trial to Assess Cooling as an Adjunctive Therapy to PCI In Patients With Acute MI (Phase A) [NA]
This update notes that the STEMI Cool Pilot Trial evaluating cooling as an adjunct to PCI for acute myocardial infarction has been withdrawn…
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CLINICAL_TRIALS withdrawal · 2025-09-25Clinical Trial Update: Safety and Efficacy Study of Gene Therapy for Acute Myocardial Infarction in Korea [Phase 2]
A Phase 2 safety and efficacy trial of a gene therapy for acute myocardial infarction in Korea has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-09-05Clinical Trial Update: Addressing Social Vulnerabilities in Cardiovascular Disease [NA]
A UCSF-sponsored clinical trial addressing social vulnerabilities in cardiovascular disease has been withdrawn. The study targeted congestiv…
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CLINICAL_TRIALS withdrawal · 2025-06-08Clinical Trial Update: Hyperoxemic Oxygen Therapy in Patients With Acute Anterior Myocardial Infarction [NA]
A clinical trial evaluating hyperoxemic oxygen therapy in patients with acute anterior myocardial infarction has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-03-17Clinical Trial Update: Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) [Phase 4]
The Phase 4 ART-CAP trial evaluating aggressive risk-prevention therapies for coronary atherosclerotic plaque has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-08-23Clinical Trial Update: Metabolic Substrate of Patients With Myocardial Infarction With and Without Modifiable Cardiovascular Risk Factors
A clinical trial evaluating metabolic substrates in patients with acute myocardial infarction, comparing those with and without modifiable c…
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CLINICAL_TRIALS withdrawal · 2024-05-17Clinical Trial Update: Adenosine's Effect on STunning Resolution in Acute Myocardial Infarction [Phase 3]
Phase 3 trial evaluating adenosine's effect on resolution of myocardial stunning after acute myocardial infarction has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-05-02Clinical Trial Update: Inflammatory Cell Trafficking After Myocardial Infarction [NA]
A clinical trial investigating inflammatory cell trafficking after myocardial infarction has been withdrawn from the registry. The sponsor l…
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EMA withdrawal · 2021-01-25EMA Withdrawn: Clopidogrel ratiopharm GmbH (clopidogrel) — Archie Samiel s.r.o.
EMA withdrew clopidogrel from Archie Samiel s.r.o.'s product line, with therapeutic areas including peripheral vascular diseases, acute coro…
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CLINICAL_TRIALS withdrawal · 2019-11-21Clinical Trial Update: Effect of Testosterone Replacement on Exercise Capacity in Hypogonadal Men After a Recent Myocardial Infarction [Phase 2, Phase 3]
A clinical trial evaluating testosterone replacement to improve exercise capacity in hypogonadal men after acute myocardial infarction has b…
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CLINICAL_TRIALS withdrawal · 2019-06-13Clinical Trial Update: Early Alirocumab to Reduce LDL-C in Myocardial Infarction [Phase 4]
Phase 4 trial investigating alirocumab to reduce LDL-C in patients with myocardial infarction was withdrawn.
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EMA withdrawal · 2019-05-07EMA Application withdrawn: Canakinumab Novartis (Canakinumab) — Novartis Europharm Limited
The EMA has withdrawn the application for canakinumab by Novartis Europharm Limited for indications in acute coronary syndrome, myocardial i…
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CLINICAL_TRIALS withdrawal · 2019-04-18Clinical Trial Update: Mechanistic Effects of Colchicine in Patients With Myocardial Infarction [Phase 4]
A Phase 4 trial investigating mechanistic effects of colchicine in myocardial infarction has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-05-31Clinical Trial Update: Safety of Topical Tranexamic Acid in Total Joint Arthroplasty in High Risk Patients [Phase 4]
The Phase 4 trial evaluating the safety of topical tranexamic acid in high-risk total joint arthroplasty patients was withdrawn. The safety …
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CLINICAL_TRIALS withdrawal · 2018-03-13Clinical Trial Update: Aggrastat Truncated Length Against Standard Therapies in Percutaneous Coronary Intervention [Phase 3]
Phase 3 trial of Aggrastat (tirofiban) in patients undergoing percutaneous coronary intervention for myocardial infarction or acute coronary…
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EMA withdrawal · 2018-01-04EMA Withdrawn: Clopidogrel Acino (clopidogrel) — Acino AG
Clopidogrel Acino has been withdrawn from the European market.
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EMA withdrawal · 2017-10-24EMA Withdrawn: Clopidogrel Teva Pharma (previously Clopidogrel HCS) (clopidogrel (as hydrochloride)) — Teva B.V.
EMA withdrew Clopidogrel Teva Pharma (clopidogrel hydrochloride) from the market.
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EMA withdrawal · 2017-09-20EMA Withdrawn: Zontivity (vorapaxar sulfate) — Merck Sharp Dohme Limited
EU withdrawal of Zontivity (vorapaxar sulfate) from the market.
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CLINICAL_TRIALS withdrawal · 2017-07-21Clinical Trial Update: Study to Assess the Safety and Cardiovascular Effects of Autologous Adipose-Derived Stromal Cells Implantation In Patients During the Acute Recovery Phase of ST-Elevation Myocardial Infarction [NA]
A clinical trial evaluating autologous adipose-derived stromal cell implantation for safety and cardiovascular effects in the acute recovery…
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CLINICAL_TRIALS withdrawal · 2017-06-12Clinical Trial Update: CANARY: Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow [NA]
CANARY trial assessing near-infrared spectroscopy for rupture-prone yellow plaques in coronary disease has been terminated.
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EMA withdrawal · 2017-04-28EMA Withdrawn: Clopidogrel/Acetylsalicylic acid Teva (clopidogrel;acetylsalicylic acid) — Teva Pharma B.V.
The EMA withdrew Teva's clopidogrel/acetylsalicylic acid combination product from the market.
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CLINICAL_TRIALS withdrawal · 2017-04-17Clinical Trial Update: A Phase 1 Safety Study of the Intravenous Administration of Thymosin Beta in Healthy Volunteers [Phase 1]
Phase 1 safety study of intravenous thymosin beta in healthy volunteers sponsored by RegeneRx Biopharmaceuticals has been withdrawn; the tri…
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CLINICAL_TRIALS withdrawal · 2017-02-08Clinical Trial Update: T2 Heart Mapping in AMI Population for the Prediction of Short Term Major Adverse Cardiovascular Events
A clinical trial evaluating T2 Heart Mapping in patients with acute myocardial infarction for predicting short-term major adverse cardiovasc…
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CLINICAL_TRIALS withdrawal · 2016-11-09Clinical Trial Update: Analyzing Gene Regions That May Interact With the Effectiveness of High Blood Pressure Drugs
A University of Washington-sponsored clinical trial examining gene regions that may influence the effectiveness of antihypertensive drugs ha…
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CLINICAL_TRIALS withdrawal · 2016-06-23Clinical Trial Update: Measurement of Matrix Metalloproteinase Activation Post Myocardial Infarction
A clinical trial evaluating matrix metalloproteinase activation after acute myocardial infarction was withdrawn from the study.