Myelofibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Comparing Momelotinib and Ruxolitinib in People With Untreated Myelofibrosis and Low Blood Cell Counts [Phase 4]
This clinical trial update describes a Phase 4 study comparing momelotinib to ruxolitinib in adults with untreated myelofibrosis and low blo…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: ENERGIA: Personalized Exercise Program for Fatigue in Patients With Myeloproliferative Neoplasms and Chronic Myeloid Leukemia [NA]
The ENERGIA study tests a personalized exercise program to reduce fatigue in patients with myeloproliferative neoplasms and chronic myeloid …
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Fedratinib in Combination With Nivolumab [Phase 2]
This Phase 2 trial evaluates the combination of fedratinib and nivolumab in patients with Primary myelofibrosis or Secondary myelofibrosis a…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Clinical Trial of Flonoltinib Maleate Tablets in the Treatment of JAK Inhibitor Refractory/Relapsed/Intolerant Patients With Medium to High Risk Myelofibrosis [Phase 2]
This is a Phase 2 clinical trial evaluating Flonoltinib Maleate Tablets in patients with medium to high-risk myelofibrosis who are refractor…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: To Evaluate the Pharmacokinetics and Safety of TQ05105 Tablet in Hepatic Impairment Subjects [Phase 1]
This Phase 1 study evaluates the pharmacokinetics and safety of TQ05105 Tablet in hepatic impairment subjects with myelofibrosis, and the tr…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Telehealth Advance Care Planning Intervention [NA]
An ongoing clinical trial at the University of Rochester is evaluating a telehealth advance care planning intervention for myeloid malignanc…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis [Phase 1, Phase 2]
Recruiting for a phase 1/2 study combining ruxolitinib with ulixertinib in patients with myelofibrosis.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017) [Phase 3]
Phase 3 study of bomedemstat (MK-3543-017) sponsored by Merck is currently recruiting to evaluate safety and efficacy in essential thrombocy…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With Myelofibrosis [Phase 1]
Phase 1 study evaluating pelabresib added to ruxolitinib in Japanese adults with myelofibrosis (primary, post-polycythemia vera, or post-ess…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms [Phase 1]
An update on a Phase 1 safety and tolerability study of INCB057643 in myelofibrosis and other advanced myeloid neoplasms, with the trial cur…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Ruxolitinib Phosphate and Azacytidine in Treating Patients With Myelofibrosis or Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
This Phase 2 trial update reports completion of a study evaluating the combination of ruxolitinib phosphate and azacitidine in patients with…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Momelotinib During and After HCT in Myelofibrosis [Phase 1]
A Phase 1 clinical trial evaluating momelotinib during and after hematopoietic cell transplantation in patients with myelofibrosis is curren…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms [Phase 1]
Phase 1 study of PRT12396 in select myeloproliferative neoplasms is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Registry Platform Myelofibrosis and Anemia
A ClinicalTrials.gov registry entry for a recruiting trial by iOMEDICO AG focused on myelofibrosis and anemia. It lists several MF-related c…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers [Phase 1]
Phase 1 trial update for IOA-244, a PI3Kδ inhibitor, being studied in metastatic cancers with status currently ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Evaluate Safety , Efficacy and Pharmacokinetics of WJ01024 Tablets Combined With Ruxolitinib in Patients With Myelofibrosis [Phase 1, Phase 2]
A phase 1/2 clinical trial update evaluating safety, efficacy, and pharmacokinetics of WJ01024 tablets in combination with ruxolitinib for i…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating CMV-MVA Triplex Vaccine to enhance CMV-specific immunity and prevent CMV viremia in patients undergoing ha…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF) [Phase 1]
CERo Therapeutics is conducting a Phase 1 trial of CER-1236 for acute myeloid leukemia, myelodysplastic syndrome, and myelofibrosis; the stu…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i) [Phase 1]
Phase 1 study of AJ1-11095 in patients with primary myelofibrosis and post-polycythemia vera or post-essential thrombocythemia myelofibrosis…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms [Phase 2]
Phase 2 clinical trial evaluating curcumin to improve inflammation and symptoms in patients with clonal cytopenia of undetermined significan…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: TP-3654 Food Effect Study [Phase 1]
Phase 1 food-effect study of TP-3654 in myelofibrosis has completed.
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis [Phase 3]
A Phase 3 trial evaluating navitoclax in combination with ruxolitinib versus ruxolitinib alone in adults with myelofibrosis has completed an…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Study of Canakinumab in Patients With Myelofibrosis [Phase 2]
A Phase 2 clinical trial evaluating canakinumab in patients with myelofibrosis is currently recruiting.
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FDA label_change · 2026-03-18FDA Approved: INREBIC — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for INREBIC (fedratinib hydrochloride) submitted by Celgene, resulting in an updated label for the p…
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FDA approval · 2026-03-18FDA Approved: OJJAARA — Supplemental Application (GlaxoSmithKline LLC)
The FDA approved a supplemental application for OJJAARA (momelotinib) from GlaxoSmithKline LLC.