Myelofibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-12-07Clinical Trial Update: Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor [Phase 2]
Phase 2 study evaluating parathyroid hormone after sequential cord blood transplantation from an unrelated donor; the trial was terminated a…
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CLINICAL_TRIALS trial_result · 2012-11-15Clinical Trial Update: A Phase 2 Study With IPI-926 in Patients With Myelofibrosis [Phase 2]
This entry notes the completion of a Phase 2 study of IPI-926 (saridegib) in patients with primary myelofibrosis.
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CLINICAL_TRIALS trial_result · 2012-08-14Clinical Trial Update: Sunitinib in Treating Patients With Idiopathic Myelofibrosis [Phase 2]
Phase 2 trial of sunitinib in patients with primary myelofibrosis was terminated; results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-08-02Clinical Trial Update: Open Label Ruxolitinib (INCB018424) in Patients With Myelofibrosis and Post Polycythemia Vera/Essential Thrombocythemia Myelofibrosis [Phase 1, Phase 2]
Open-label Phase 1/2 trial results for ruxolitinib (INCB018424) in patients with myelofibrosis, including those with post-polycythemia vera/…
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CLINICAL_TRIALS trial_result · 2012-06-12Clinical Trial Update: Bone Marrow Transplantation in Treating Patients With Multiple Myeloma, Chronic Phase Chronic Myelogenous Leukemia, or Agnogenic Myeloid Metaplasia [Phase 2]
Phase 2 clinical trial update on bone marrow transplantation for patients with multiple myeloma, chronic myeloid leukemia (chronic phase), o…
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CLINICAL_TRIALS trial_result · 2012-05-30Clinical Trial Update: Controlled Myelofibrosis Study With Oral Janus-associated Kinase (JAK) Inhibitor Treatment-II: The COMFORT-II Trial [Phase 3]
Phase 3 COMFORT-II trial evaluating a JAK inhibitor for myelofibrosis has completed with posted results.
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CLINICAL_TRIALS trial_result · 2012-04-20Clinical Trial Update: A Phase 1/2 Study of SB1518 for the Treatment of Advanced Myeloid Malignancies [Phase 1, Phase 2]
This document provides an update on the completed Phase 1/2 trial of SB1518 for advanced myeloid malignancies.
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CLINICAL_TRIALS trial_result · 2012-04-20Clinical Trial Update: A Phase 1/2 Study of Oral SB1518 in Subjects With Chronic Idiopathic Myelofibrosis [Phase 1, Phase 2]
The Phase 1/2 study of oral SB1518 (pacritinib) in chronic idiopathic myelofibrosis has completed, with the trial listing other myeloprolife…
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CLINICAL_TRIALS trial_result · 2012-04-02Clinical Trial Update: Low-Dose Decitabine in Treating Patients With Symptomatic Myelofibrosis [Phase 2]
Phase 2 trial evaluating low-dose decitabine for symptomatic myelofibrosis was terminated, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-01-24Clinical Trial Update: COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial [Phase 3]
Phase 3 COMFORT-I trial evaluating the oral JAK inhibitor ruxolitinib for myelofibrosis completed, with results posted.
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CLINICAL_TRIALS trial_result · 2012-01-20Clinical Trial Update: PTK 787 and Gleevec in Patients With AML, AMM, and CML-BP [Phase 1, Phase 2]
This clinical trial update reports Phase 1/Phase 2 results for the combination of PTK 787 and imatinib (Gleevec) in patients with acute myel…
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CLINICAL_TRIALS trial_result · 2012-01-13Clinical Trial Update: Imatinib Mesylate in Treating Patients With Myelofibrosis [Phase 2]
Phase 2 trial evaluating imatinib mesylate in patients with primary myelofibrosis. The study was terminated and results were posted in Janua…
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CLINICAL_TRIALS trial_result · 2011-05-04Clinical Trial Update: CEP-701 for PH-negative Myelofibrosis [Phase 2]
Phase 2 clinical trial of CEP-701 (lestaurtinib) for PH-negative myelofibrosis completed, with results posted in May 2011.
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CLINICAL_TRIALS trial_result · 2011-05-02Clinical Trial Update: Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload [Phase 3]
This Phase 3 expanded-access update describes deferasirox use for patients with congenital disorders of red blood cells and chronic iron ove…
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CLINICAL_TRIALS trial_result · 2011-04-08Clinical Trial Update: Assessment of Labile Plasma Iron (LPI) in Myelodysplastic Syndromes (MDS) and Primary Myelofibrosis
This clinical trial update assesses labile plasma iron (LPI) in patients with myelodysplastic syndromes and primary myelofibrosis; the curre…
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CLINICAL_TRIALS trial_result · 2011-04-05Clinical Trial Update: A Safety Study of XL019 in Adults With Myelofibrosis [Phase 1]
This clinical trial update reports termination of a Phase 1 safety study of XL019 in adults with myelofibrosis and related myeloproliferativ…
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CLINICAL_TRIALS trial_result · 2011-03-30Clinical Trial Update: Ph II Study of Azacitidine in Myelofibrosis [Phase 2]
A Phase II study of azacitidine in myelofibrosis has completed and results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-03-17Clinical Trial Update: Thalidomide, Prednisone, and Cyclophosphamide in Treating Patients With Myelofibrosis and Myeloid Metaplasia [Phase 2]
Phase 2 trial evaluating thalidomide, prednisone, and cyclophosphamide in patients with myelofibrosis and myeloid metaplasia; the study has …
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CLINICAL_TRIALS trial_result · 2011-02-21Clinical Trial Update: A Phase II Study of CC-5013 in Myelofibrosis [Phase 2]
Phase II study of CC-5013 in myelofibrosis has completed and posted results.
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Azacitidine in Treating Patients With Myelofibrosis [Phase 2]
A Phase 2 trial of azacitidine in patients with myelofibrosis was terminated; results were posted in January 2011.
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CLINICAL_TRIALS trial_result · 2010-06-17Clinical Trial Update: Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating chemotherapy followed by peripheral stem cell transplantation in patients with myelofibrosis; the study ha…
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CLINICAL_TRIALS trial_result · 2009-10-26Clinical Trial Update: A Dose-escalation Study of the Safety and Tolerability of Orally Administered TG101348 in Patients With Myelofibrosis [Phase 1]
This Phase 1 dose-escalation study reports on the safety and tolerability of orally administered TG101348 in patients with myelofibrosis.
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CLINICAL_TRIALS trial_result · 2009-05-05Clinical Trial Update: A Phase 1 Study of MKC-1 in Patients With Refractory Hematologic Malignancies [Phase 1]
This document reports a Phase 1 trial of MKC-1 in patients with refractory hematologic malignancies, including myelodysplastic syndromes and…