Myelofibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED) [Phase 2]
Completed Phase 2 study of AP23573 (ridaforolimus) in patients with relapsed or refractory hematologic malignancies, including leukemia, mye…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias [Phase 1]
Phase 1 study of TH-302 (evofosfamide), a hypoxia-activated prodrug, in patients with advanced leukemias has been completed, with evaluation…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: LBH589 (Panobinostat) for the Treatment of Myelofibrosis [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial update for LBH589 (panobinostat) in myelofibrosis with current status not reported.
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CLINICAL_TRIALS trial_result · 2015-03-03Clinical Trial Update: Exploratory Phase II Study of INC424 Patients With Primary Myelofibrosis (PMF) or Post Polycythaemia Myelofibrosis (PPV MF) or Post Essential Thrombocythaemia Myelofibrosis (PET-MF) [Phase 4]
Completed Phase 4 exploratory study of INC424 (nilotinib) in patients with primary myelofibrosis or post-polycythemia vera myelofibrosis or …
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CLINICAL_TRIALS trial_result · 2015-01-05Clinical Trial Update: Decitabine in Treating Patients With Myelofibrosis [Phase 2]
Phase 2 results from a decitabine trial in myelofibrosis have been posted. The study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases [Phase 1]
Phase 1 trial update on belinostat plus azacitidine in adults with advanced hematologic cancers. The study has completed enrollment and eval…
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CLINICAL_TRIALS trial_result · 2014-12-09Clinical Trial Update: A Trial of Zoledronic Acid in Patients With Myelofibrosis With Myeloid Metaplasia (MMM) [Phase 2]
Phase 2 trial evaluating zoledronic acid in patients with myelofibrosis with myeloid metaplasia has completed.
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CLINICAL_TRIALS trial_result · 2014-09-19Clinical Trial Update: Alternative Dosing Strategy of Ruxolitinib in Patients With Myelofibrosis [Phase 2]
A Phase 2 trial investigates an alternative dosing strategy for ruxolitinib in myelofibrosis, with completed results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-28Clinical Trial Update: Anti-TGF-beta Therapy in Patients With Myelofibrosis [Phase 1]
Phase 1 trial evaluating an anti-TGF-beta therapy in myelofibrosis was terminated; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Phase II Study of Bevacizumab (Avastin®) in Myelofibrosis [Phase 2]
A Phase II trial of bevacizumab in myelofibrosis was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer [Phase 2]
This Phase 2 trial tested sirolimus, tacrolimus, and antithymocyte globulin for preventing graft-versus-host disease in patients undergoing …
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CLINICAL_TRIALS trial_result · 2014-05-21Clinical Trial Update: 3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating the combination of Triapine (3-AP) and fludarabine in various myeloproliferative disorders and advanced phases of c…
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CLINICAL_TRIALS trial_result · 2014-05-16Clinical Trial Update: Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants [Phase 1]
Phase 1 trial evaluating total body irradiation with fludarabine followed by combined umbilical cord blood transplants has completed. The tr…
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: CC-4047 in Treating Patients With Myelofibrosis [Phase 1, Phase 2]
Phase 1/2 clinical trial of CC-4047 in patients with chronic myeloproliferative disorders and secondary myelofibrosis has completed with res…
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: Study of Pomalidomide in Persons With Myeloproliferative-Neoplasm-Associated Myelofibrosis and RBC-Transfusion-Dependence [Phase 3]
Phase 3 trial of pomalidomide in myeloproliferative neoplasm-associated myelofibrosis and RBC-transfusion-dependence completed in 2014.
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Sibling Donor Peripheral Stem Cell Transplant or Sibling Donor Bone Marrow Transplant in Treating Patients With Hematologic Cancers or Other Diseases [Phase 3]
Phase 3 trial comparing sibling donor peripheral blood stem cell transplant versus sibling donor bone marrow transplant in hematologic disea…
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CLINICAL_TRIALS trial_result · 2014-02-25Clinical Trial Update: Imatinib Mesylate in Treating Patients With Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating Imatinib Mesylate in patients with myelofibrosis has completed. The study also addresses related myeloprol…
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CLINICAL_TRIALS trial_result · 2014-01-30Clinical Trial Update: Study of SB939 in Subjects With Myelofibrosis [Phase 2]
Phase 2 study of the investigational drug SB939 in patients with myelofibrosis has completed, with results posted in January 2014.
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CLINICAL_TRIALS trial_result · 2013-10-28Clinical Trial Update: A Phase II Study of Pomalidomide in Myelofibrosis With Myeloid Metaplasia [Phase 2]
Phase II study evaluating pomalidomide in myelofibrosis with myeloid metaplasia completed with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-10-08Clinical Trial Update: Thalidomide in Treating Patients With Myelofibrosis [Phase 2]
A Phase 2 clinical trial evaluating thalidomide for primary myelofibrosis has completed.
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CLINICAL_TRIALS trial_result · 2013-09-26Clinical Trial Update: Lenalidomide and Prednisone in Treating Patients With Myelofibrosis [Phase 2]
This Phase 2 trial evaluated lenalidomide in combination with prednisone for patients with myelofibrosis and related myeloproliferative neop…
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CLINICAL_TRIALS trial_result · 2013-09-25Clinical Trial Update: Study of Ruxolitinib (INCB018424) Sustained Release Formulation in Myelofibrosis Patients [Phase 2]
This clinical trial update reports results from a Phase 2 study of a sustained-release formulation of ruxolitinib in myelofibrosis, with res…
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CLINICAL_TRIALS trial_result · 2013-08-26Clinical Trial Update: Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in the Treatment of Myelofibrosis With Myeloid Metaplasia [Phase 2]
A Phase 2 trial assessing the safety and efficacy of Obatoclax Mesylate (GX15-070MS) in patients with myelofibrosis (myelofibrosis with myel…
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CLINICAL_TRIALS trial_result · 2013-06-17Clinical Trial Update: Plasma Vitamin and Homocysteine Levels and Thrombosis in Patients With Ph-negative MPNs
This clinical trial update reports on plasma vitamin and homocysteine levels and thrombosis in patients with Philadelphia-negative myeloprol…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Tipifarnib in Treating Patients With Myelofibrosis and Myeloid Metaplasia [Phase 2]
Phase 2 clinical trial update on tipifarnib for myelofibrosis and related myeloproliferative disorders, with the study having completed.