Myelofibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-12-24Clinical Trial Update: Reduced Intensity Allogeneic PBSCT to Treat Hematologic Malignancies and Hematopoietic Failure States [Phase 2]
Phase 2 trial investigating reduced-intensity allogeneic peripheral blood stem cell transplantation for hematologic malignancies and hematop…
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CLINICAL_TRIALS trial_result · 2018-12-04Clinical Trial Update: Allogeneic Stem Cell Transplantation for Myelofibrosis and Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial update on allogeneic stem cell transplantation for myelofibrosis (and related myelodysplastic syndromes) completed wi…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Pegylated Interferon Alpha-2b in Early Primary Myelofibrosis [Phase 2]
Phase 2 study of pegylated interferon alpha-2b in early primary myelofibrosis; the trial was terminated and results were posted.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Vismodegib in Combination With Ruxolitinib for the Treatment of Intermediate- or High-Risk Myelofibrosis (MF) [Phase 1]
This update notes the completion of a Phase 1 study evaluating vismodegib in combination with ruxolitinib for intermediate- or high-risk mye…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: A Study in Myeloproliferative Disorders [Phase 1]
Phase 1 study in myeloproliferative neoplasms has completed, evaluating patients with essential thrombocythemia, polycythemia vera, and prim…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancer [Phase 2]
Phase 2 clinical trial evaluating busulfan, cyclophosphamide, and antithymocyte globulin followed by stem cell transplant for hematologic ca…
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: Single-Agent Glasdegib In Patients With Myelofibrosis Previously Treated With Ruxolitinib [Phase 2]
A Phase 2 trial of single-agent glasdegib in myelofibrosis patients previously treated with ruxolitinib was terminated; results were posted …
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CLINICAL_TRIALS trial_result · 2018-01-02Clinical Trial Update: Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome [NA]
Clinical trial update on cyclophosphamide and busulfan followed by donor stem cell transplant for myelofibrosis, AML, or myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases [Phase 1]
Phase 1 trial evaluating the safety of Umbilical Cord Blood T-Regulatory Cell infusion followed by donor cord blood transplant in patients w…
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Ruxolitinib Phosphate and Danazol in Treating Anemia in Patients With Myelofibrosis [Phase 2]
Phase 2 trial evaluating the combination of ruxolitinib phosphate and danazol to treat anemia in patients with primary or secondary myelofib…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies [NA]
Clinical trial update for fludarabine-based conditioning prior to allogeneic transplantation in advanced hematologic malignancies; study com…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: T-Cell Depletion, Donor Hematopoietic Stem Cell Transplant (HSCT), and T-Cell Infusions in Treating Patients With Hematologic Cancer or Other Diseases [Phase 2]
Phase 2 study evaluating T-cell depletion and donor hematopoietic stem cell transplantation with T-cell infusions in patients with various h…
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative Diseases [Phase 1]
A Phase 1 trial evaluating the safety of AZD1480 in adults with myeloproliferative diseases has completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms [Phase 1]
Phase 1 study of LY2784544 testing alternative dosing in patients with myeloproliferative neoplasms, including polycythemia vera, essential …
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Pilot Trial of Arsenic + Cytarabine in Patients With Myelofibrosis [EARLY_Phase 1]
This update reports the completion of an early-phase pilot trial testing arsenic trioxide in combination with cytarabine for myelofibrosis.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders [Phase 1, Phase 2]
A completed Phase 1/2 study from Singapore General Hospital evaluated a Traditional Chinese Medicine formulation for supportive management o…
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CLINICAL_TRIALS trial_result · 2016-12-23Clinical Trial Update: A Study of Gleevec in Patients With Idiopathic Myelofibrosis or Chronic Myelomonocytic Leukemia (CMML) [Phase 2]
Phase 2 study evaluating imatinib (Gleevec) in patients with myelofibrosis and chronic myelomonocytic leukemia has completed. The study was …
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: A Clinical Study of Ruxolitinib in Patients With Primary Myelofibrosis (PM), Post-polycythemia Vera (PV) Myelofibrosis, or Post-essential Thrombocythemia (ET) Myelofibrosis [Phase 3]
Phase 3 trial of ruxolitinib in primary myelofibrosis and related post-PV/post-ET myelofibrosis has completed, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-05-23Clinical Trial Update: HSP90 Inhibitor, AUY922, in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF), and Refractory PV/ET [Phase 2]
Phase 2 trial of the HSP90 inhibitor AUY922 in myeloproliferative neoplasms including primary myelofibrosis and MF after PV/ET was terminate…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Study of Fludarabine Based Conditioning for Allogeneic Stem Cell Transplantation for Myelofibrosis [Phase 2]
A Phase 2 study evaluated a fludarabine-based conditioning regimen before allogeneic stem cell transplantation in myelofibrosis, with result…
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Reversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder
This clinical trial update notes termination of NCT00722254, a University of Utah study investigating reversible secondary myelofibrosis or …
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: Phase I Clinical Study of CWP232291 in Acute Myeloid Leukemia Patients [Phase 1]
Phase I study of CWP232291 in patients with acute myeloid leukemia and related myeloid neoplasms has completed.
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: A Phase II Study of Re-treatment of Myelofibrosis Patients With Ruxolitinib/Jakavi After Treatment Interruption Due to Loss of Response and/or Adverse Event (ReTreatment Trial) [Phase 2]
Phase II study evaluating re-treatment with ruxolitinib in patients with primary myelofibrosis after interruption due to loss of response or…
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Allogeneic Stem Cell Transplantation (SCT) After Dose-reduced Conditioning for Myelofibrosis Patients [Phase 2]
Phase 2 clinical trial evaluating allogeneic stem cell transplantation with dose-reduced conditioning in patients with myelofibrosis; the st…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Study of KB004 in Subjects With Hematologic Malignancies (Myelodysplastic Syndrome, MDS, Myelofibrosis, MF) [Phase 1, Phase 2]
A Phase 1/2 study of KB004 in myelodysplastic syndrome and myelofibrosis, sponsored by Humanigen, Inc., is currently suspended.