Myelofibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: Study of Jaktinib In Patients With Myelofibrosis Who Were Relapsed or Refractory of Ruxolitinib Treatment. [Phase 2]
Phase 2 trial update of Jaktinib in relapsed/refractory myelofibrosis patients previously treated with ruxolitinib has completed.
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Panobinostat and Ruxolitinib In MyElofibrosis (PRIME Trial) [Phase 1, Phase 2]
Phase 1/2 trial evaluating panobinostat and ruxolitinib in myelofibrosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Methods of T Cell Depletion Trial (MoTD) [Phase 2]
Phase 2 trial update for methods of T cell depletion in various hematologic malignancies is ongoing.
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation [Phase 2]
Phase 2 study evaluating a combination of Itacitinib, Tacrolimus, and Sirolimus for prevention of graft-versus-host disease in patients with…
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CLINICAL_TRIALS trial_result · 2023-08-24Clinical Trial Update: A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence [Phase 2]
Phase 2 trial evaluating luspatercept for anemia in patients with myeloproliferative neoplasm-associated myelofibrosis; study completed with…
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CLINICAL_TRIALS trial_result · 2023-07-12Clinical Trial Update: Vaccine Therapy in Reducing the Frequency of Cytomegalovirus Events in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating a vaccine therapy to reduce cytomegalovirus events in patients with hematologic malignancies undergoing donor stem …
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CLINICAL_TRIALS trial_result · 2023-06-07Clinical Trial Update: A Phase 1/2 Study To Evaluate ASN002 In Relapsed/Refractory Lymphoma And Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial update for ASN002 in relapsed/refractory lymphoma and advanced solid tumors; the study status is TERMINATED with re…
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CLINICAL_TRIALS trial_result · 2023-06-06Clinical Trial Update: LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating LCL161 in patients with various forms of myelofibrosis has completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-06-06Clinical Trial Update: Sotatercept in Treating Patients With Myeloproliferative Neoplasm-Associated Myelofibrosis or Anemia [Phase 2]
Phase 2 trial of sotatercept in patients with myeloproliferative neoplasm-associated myelofibrosis or anemia has completed with results post…
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CLINICAL_TRIALS trial_result · 2023-05-23Clinical Trial Update: Efficacy of Momelotinib Versus Best Available Therapy in Anemic or Thrombocytopenic Subjects With Primary Myelofibrosis (MF), Post-polycythemia Vera MF, or Post-essential Thrombocythemia MF [Phase 3]
Phase 3 trial comparing momelotinib to best available therapy in anemic or thrombocytopenic patients with various subtypes of myelofibrosis;…
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CLINICAL_TRIALS trial_result · 2023-05-23Clinical Trial Update: Bomedemstat (IMG-7289) Plus Ruxolitinib for Myelofibrosis [Phase 2]
Phase 2 clinical trial investigating Bomedemstat (IMG-7289) in combination with Ruxolitinib for myelofibrosis.
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CLINICAL_TRIALS trial_result · 2023-05-12Clinical Trial Update: Momelotinib Versus Ruxolitinib in Subjects With Myelofibrosis [Phase 3]
Phase 3 trial comparing momelotinib to ruxolitinib in myelofibrosis subjects has completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-04-28Clinical Trial Update: KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment [Phase 2, Phase 3]
Clinical trial updating the efficacy of KRT-232 versus best available therapy for relapsed/refractory myelofibrosis (Phase 2/Phase 3).
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CLINICAL_TRIALS trial_result · 2023-04-27Clinical Trial Update: Reduced Intensity Conditioning Transplant Using Haploidentical Donors [Phase 2]
Phase 2 clinical trial investigating reduced intensity conditioning transplant using haploidentical donors for various hematologic malignanc…
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CLINICAL_TRIALS trial_result · 2023-04-20Clinical Trial Update: Jaktinib for the Treatment of Ruxolitinib Intolerance of Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating jaktinib for patients with myelofibrosis intolerant to ruxolitinib has completed.
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: Thymoglobuline Versus Alemtuzumab in Patients Undergoing Allogeneic Transplant [Phase 2, Phase 3]
A Phase 2/3 clinical trial comparing thymoglobulin to alemtuzumab in patients undergoing allogeneic stem cell transplantation has been compl…
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: A Trial of Fedratinib in Subjects With DIPSS, Intermediate or High-Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib [Phase 3]
A Phase 3 trial of fedratinib in patients with primary myelofibrosis and myelofibrosis after polycythemia vera or essential thrombocythemia …
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy [Phase 2, Phase 3]
Clinical trial updates for eltrombopag olamine in thrombocytopenia associated with chronic myeloid leukemia or myelofibrosis during tyrosine…
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CLINICAL_TRIALS trial_result · 2022-12-22Clinical Trial Update: A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM) [Phase 3]
Phase 3 trial comparing momelotinib to danazol in symptomatic and anemic myelofibrosis has completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-11-29Clinical Trial Update: Jaktinib Hydrochloride Tablets in Intermediate-risk and High-risk Myelofibrosis. [Phase 2]
Phase 2 trial update for jaktinib hydrochloride tablets in intermediate- and high-risk myelofibrosis has completed.
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies [Phase 2]
Phase 2 clinical trial update on shorter course tacrolimus after non-myeloablative conditioning with related donor PBSCT and high-dose postt…
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CLINICAL_TRIALS trial_result · 2022-10-06Clinical Trial Update: Ropeginterferon Alfa 2b for Early Myelofibrosis [Phase 2]
Phase 2 clinical trial investigating Ropeginterferon Alfa 2b for early myelofibrosis; current status is unknown.
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CLINICAL_TRIALS trial_result · 2022-08-22Clinical Trial Update: Myelofibrosis Treated With Pacritinib Before aSCT. (HOVON134MF) [Phase 2]
A Phase 2 clinical trial updating results for myelofibrosis treated with pacritinib prior to allogeneic stem cell transplantation (HOVON134M…
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: JAK2 Inhibitors RUXOLITINIB in Patients With Myelofibrosis [Phase 2]
Phase 2 trial update of ruxolitinib in myelofibrosis completed.
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Trial Ruxolitinib and Peg-interferon Alpha-2a Combination in Patients With Primary Myelofibrosis RUXOPeg [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of ruxolitinib and peg-interferon alfa-2a in patients with myelofibrosis has completed.