Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating cyclophosphamide as GVHD prophylaxis after allogeneic peripheral blood stem cell transplantation in patients with h…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases [Phase 3]
Phase 3 trial evaluating donor bone marrow transplant with or without G-CSF in young patients with hematologic cancers or related diseases; …
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant [Phase 3]
A Phase 3 trial of moxifloxacin to prevent bacterial infections in patients who have undergone a donor stem cell transplant was terminated.
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Donor Peripheral Stem Cell Transplant, Fludarabine, and Busulfan in Treating Patients With Hematologic Cancers [Phase 2]
Phase 2 trial assessing donor peripheral stem cell transplant with fludarabine and busulfan in hematologic cancers has completed; results po…
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CLINICAL_TRIALS withdrawal · 2017-05-08Clinical Trial Update: Pacritinib in Combination With Low Dose Decitabine in Intermediate-High Risk Myelofibrosis or Myeloproliferative Neoplasm (MPN)/Myelodysplastic Syndrome (MDS) [Phase 1]
A Phase 1 trial evaluating pacritinib in combination with low-dose decitabine for intermediate-high risk myelofibrosis and related myeloprol…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors [Phase 2]
Phase 2 clinical trial evaluating the combination of plerixafor and GM-CSF (sargramostim) for mobilizing hematopoietic stem cells from allog…
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CLINICAL_TRIALS withdrawal · 2017-05-03Clinical Trial Update: A Clinical Trial of Omacetaxine, Azacitidine, and Growth-Colony Stimulating Factor (G-CSF) for Myelodysplastic Syndromes (MDS) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating omacetaxine, azacitidine, and G-CSF for myelodysplastic syndromes has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Study to Determine the Safety and Preliminary Efficacy of CC-1088 in the Treatment of Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial investigating CC-1088 for myelodysplastic syndromes has completed, reporting safety and preliminary efficacy results.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating MS-275 (entinostat) in combination with GM-CSF in adults with myelodysplastic syndromes and/or relapsed or refracto…
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CLINICAL_TRIALS safety_alert · 2017-04-17Clinical Trial Update: Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone
Clinical trial update reports methemoglobinemia risk in young patients with hematologic cancers or aplastic anemia treated with dapsone in a…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay [NA]
Clinical trial update on using a high-throughput drug sensitivity assay to guide treatment for relapsed/refractory acute myeloid leukemia.
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CLINICAL_TRIALS research · 2017-04-13Clinical Trial Update: B7.1/IL-2 Leukaemia Cell Vaccine for Non-Transplant AML RFUSIN2-AML2 (NTX) [Phase 1]
Phase 1 clinical trial update of a B7.1/IL-2 leukemia cell vaccine for non-transplant acute myeloid leukemia and myelodysplastic syndromes; …
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant [Phase 1]
A Phase 1 trial evaluating rasburicase to prevent graft-versus-host disease in patients undergoing donor stem cell transplantation; the stud…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders [Phase 2]
Phase 2 clinical trial evaluating nonmyeloablative allogeneic stem cell transplantation for various hematologic disorders has completed.
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapy [Phase 1]
This Phase 1 trial update reports on transplantation using specially treated bone marrow for hematologic cancers that have not responded to …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Long Term Safety Study of SyB L-1101 in Patients With Recurrent/Relapsed or Refractory Myelodysplastic Syndrome (MDS) - Extension Study [Phase 1]
Long-term safety results from a Phase 1 extension study of SyB L-1101 in patients with recurrent/relapsed or refractory myelodysplastic synd…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Decitabine Followed by Idarubicin and Cytarabine in Treating Patients With Relapsed or Refractory AML and MDS [Phase 2]
Phase 2 clinical trial evaluated a sequence of decitabine followed by idarubicin and cytarabine in adults with relapsed or refractory acute …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [NA]
A terminated clinical trial evaluated mobilizing donor peripheral blood stem cells with plerixafor and filgrastim before donor transplant in…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Safety Assessment of Two Schedules of Intravenous Infusions of SNS-595 for the Treatment of Hematologic Malignancies [Phase 1]
Phase 1 clinical trial update describing safety assessments for two infusion schedules of SNS-595 in patients with hematologic malignancies.…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports completion of a study evaluating an investigational biological therapy in adults with advanced mye…
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating donor stem cell transplantation for patients with relapsed hematologic malignancies or secondary myelodysplasia who…
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: Plerixafor and Granulocyte Colony-stimulating Factor (G-CSF) in Combination With Azacitidine for the Treatment of Myelodysplastic Syndrome (MDS) [Phase 1]
A Phase 1 trial evaluating the combination of plerixafor and G-CSF with azacitidine for myelodysplastic syndromes has completed.
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899) [Phase 3]
This Phase 3 trial comparing posaconazole prophylaxis against standard azole therapy in neutropenic patients has completed. It includes pati…
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis [Phase 3]
A Phase 3 trial comparing cyclophosphamide with methotrexate plus a calcineurin inhibitor for GVHD prophylaxis in patients with various hema…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload [Phase 4]
Phase 4 trial assessing the efficacy of Deferasirox for iron chelation in transfusion-dependent chronic anemia due to myelodysplastic syndro…