Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy [Phase 2]
Phase 2 trial evaluating imetelstat in patients with high-risk myelodysplastic syndromes or acute myeloid leukemia after failure of hypometh…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Biologically Focused Therapy of Treatment-Refractory MDS Patients
The clinical trial evaluating a biologically focused therapy for treatment-refractory myelodysplastic syndromes has completed.
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: A Trial Testing Early vs Late Onset of EPO Alfa Treatment in Lower Risk MDS [Phase 3]
A Phase 3 trial comparing early versus late onset of epoetin alfa in lower-risk myelodysplastic syndromes. The study is currently active but…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: A Non-interventional Study of REVLIMID® (Lenalidomide) Treatment of IPSS Low- or Intermediate-1-risk Myelodysplastic Syndromes Associated With a Deletion 5q or Refractory/Relapsed Mantle Cell Lymphoma in Korea
A completed non-interventional study in Korea assessing lenalidomide (REVLIMID) for IPSS low- or intermediate-1-risk myelodysplastic syndrom…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating reduced-intensity conditioning with fludarabine and melphalan plus total body irradiation for haploidentical stem c…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: A Study of CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS [Phase 1]
A Phase 1 study evaluating CG-806 in patients with relapsed or refractory acute myeloid leukemia or higher-risk myelodysplastic syndromes ha…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Myeloablative Hematopoietic Progenitor Cell Transplantation (HPCT) for Pediatric Malignancies
This completed clinical trial evaluated myeloablative hematopoietic progenitor cell transplantation in pediatric patients with chronic myelo…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: APR-548 in Combination With Azacitidine for the Treatment of TP53 Myelodysplastic Syndromes (MDS) [Phase 1]
A Phase 1 trial of APR-548 in combination with azacitidine for TP53-mutant myelodysplastic syndromes was terminated. Results were posted in …
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Efficacy and Safety of Luspatercept: a Study by Fondazione Italiana Sindromi Mielodisplastiche
A completed clinical trial evaluating the efficacy and safety of luspatercept in myelodysplastic syndromes.
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care
A completed clinical trial program in myelodysplastic syndromes focused on genomic characterization to guide clinical decisions and the syst…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Italian Network MDS Registry
An Italian network registry study for myelodysplastic syndromes and related myeloproliferative neoplasms is currently recruiting participant…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: PTCy and ATG for MSD and MUD Transplants [Phase 1, Phase 2]
Ongoing Phase 1/2 clinical trial evaluating post-transplant cyclophosphamide and anti-thymocyte globulin for matched sibling and matched unr…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Monitoring Mutational Burden in Low Risk MDS Patients Using Sequential Peripheral Blood Samples
This clinical trial update describes a study on monitoring mutational burden in low-risk myelodysplastic syndrome patients by analyzing sequ…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies [Phase 3]
A Phase 3 randomized trial evaluating conditioning with fludarabine plus single versus dual alkylating agents in myeloid malignancies (acute…
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Study to Evaluate Imetelstat (GRN163L) in Participants With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) [Phase 2, Phase 3]
A study evaluating imetelstat (GRN163L) in IPSS low or Intermediate-1 risk myelodysplastic syndrome (MDS) across Phase 2/Phase 3, status ACT…
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Study to Evaluate Imetelstat (GRN163L) in Participants With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) [Phase 2, Phase 3]
This update reports results from a Phase 2/Phase 3 study of Imetelstat (GRN163L) in participants with IPSS low- or intermediate-1 risk myelo…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy With Hypomethylating Agents [Phase 1]
Phase 1 trial of fostamatinib for lower-risk myelodysplastic syndromes or chronic myelomonocytic leukemia after failure of hypomethylating a…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 3]
A Phase 3 clinical trial update evaluating reduced-intensity conditioning regimens for patients with acute myeloid leukemia or myelodysplast…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Telehealth Advance Care Planning Intervention for Older Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome [NA]
This clinical trial update reports results for a telehealth advance care planning intervention targeting older patients with Acute Myeloid L…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Comparison Study of Standard Care Against Combination of Growth Factors Agents for Low-risk Myelodysplastic Syndromes [Phase 3]
A completed Phase 3 trial compared standard care with a combination of growth factor agents in patients with low-risk myelodysplastic syndro…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Biocollection in MyeloDysplastic Syndrome (P-MDS) [NA]
A clinical trial update indicating that a Biocollection in Myelodysplastic Syndrome study is currently recruiting and targets several MDS su…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: Interplay Between Immune and Metabolic Programs in Myelodysplastic Syndromes
A completed clinical trial update investigates how immune and metabolic pathways interact in myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: GITMO AML/MDS-Relapse Registry Study
The GITMO AML/MDS-Relapse Registry Study has completed.
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: SGI-110 in Participants With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Clinical trial update reporting completion and posted results for SGI-110 (guadecitabine) in patients with myelodysplastic syndromes, chroni…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients [Phase 1, Phase 2]
First-in-human Phase 1/2 study of ABD-3001 to evaluate safety, tolerability, pharmacokinetics, and preliminary activity in adults with refra…