Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies [Phase 2]
Phase 2 clinical trial update describing a donor stem cell transplant conditioning regimen with treosulfan, fludarabine, and total-body irra…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies [Phase 1, Phase 2]
A first-in-human study evaluating HLA partially to fully matched allogeneic, cryopreserved deceased donor bone marrow transplantation for va…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Azacitidine and Chimerism in MDS or AML Patients After Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating azacitidine and chimerism in patients with myelodysplastic syndrome or acute myeloid leukemia after alloge…
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CLINICAL_TRIALS other · 2026-02-23Clinical Trial Update: Pre-myeloid Cancer and Bone Marrow Failure Clinic Study [NA]
A Mayo Clinic clinical trial update for a study addressing pre-myeloid cancer and inherited bone marrow failure syndromes, currently recruit…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating liposome-encapsulated daunorubicin-cytarabine (CPX-351) in combination with gemtuzumab ozogamicin for relapsed or r…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome) [Phase 1]
Phase 1 study evaluating rezatapopt in combination with azacitidine for TP53Y220C mutant myeloid malignancies (acute myeloid leukemia or mye…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Venetoclax in Combination With ASTX727 for the Treatment of Treatment-Naive High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluates venetoclax combined with ASTX727 (oral decitabine/cedazuridine) in treatment-naive high-risk myelodyspl…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Nivolumab and Ipilimumab After Donor Stem Cell Transplant in Treating Patients With High Risk Refractory or Relapsed Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 trial update evaluating the combination of nivolumab and ipilimumab after donor stem cell transplantation in patients with high-ri…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome [Phase 2]
This Phase 2 clinical trial investigates the combination of azacitidine and enasidenib for IDH2-mutant myelodysplastic syndrome and is curre…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial update evaluating busulfan, fludarabine phosphate, and post-transplant cyclophosphamide in patients with hematologi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders [Phase 2]
Phase 2 clinical trial update evaluating a geriatric assessment to guide treatment planning for older adults with myelodysplastic syndromes,…
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CLINICAL_TRIALS withdrawal · 2026-02-12Clinical Trial Update: Venetoclax and Azacitidine for the Treatment of High-Risk Recurrent or Refractory Myelodysplastic Syndrome [Phase 1, Phase 2]
A phase 1/2 clinical trial testing venetoclax in combination with azacitidine for high-risk recurrent or refractory myelodysplastic syndrome…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Cladribine Plus Low Dose Cytarabine (LDAC) Alternating With Decitabine in Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial evaluating alternating regimens of cladribine plus low-dose cytarabine with decitabine for acute myeloid leukemia or high-risk…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemia [Phase 1]
Phase I trial evaluating AZD1775 in combination with belinostat for relapsed or refractory myeloid malignancies or untreated acute myeloid l…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer [Phase 2]
Phase 2 clinical trial evaluating FLAG-Ida chemotherapy followed by reduced-intensity total body irradiation and donor hematopoietic cell tr…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH [Phase 1]
Phase 1 study of HMPL-306 in advanced hematologic cancers with IDH mutation has been terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed [Phase 1, Phase 2]
Phase 1/2 study of guadecitabine plus atezolizumab in adults with advanced myelodysplastic syndrome or chronic myelomonocytic leukemia that …
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms [Phase 1]
Phase 1 safety, tolerability and preliminary efficacy study of NC525 in adults with advanced myeloid neoplasms has been terminated and resul…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia [Phase 2]
Phase 2 clinical trial evaluating Total Marrow and Lymphoid Irradiation as a conditioning regimen before hematopoietic cell transplantation …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 2]
This Phase 2 clinical trial compares treosulfan-based versus clofarabine-based conditioning regimens before donor allogeneic stem cell trans…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Dose-Escalation Study of Oral Administration of LP-108 as Monotherapy and in Combination With Azacitidine in Patients With Relapsed or Refractory MDS, CMML, or AML [Phase 1]
Phase 1 dose-escalation trial evaluating LP-108 as monotherapy and in combination with azacitidine in adults with relapsed or refractory mye…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies [Phase 1]
Phase 1 clinical trial evaluating a CD70-directed CAR T-cell therapy for pediatric hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases [Phase 2]
Phase 2 clinical trial evaluating a cord blood transplant using cyclophosphamide, fludarabine, and total-body irradiation in high-risk hemat…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 1]
Clinical trial update indicates CLN-049 is being studied for relapsed/refractory acute myeloid leukemia and myelodysplastic syndrome in a Ph…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Orca-T Expanded Access Program Study for Patients With Advanced Hematologic Malignancies
The Orca-T Expanded Access Program study for patients with advanced hematologic malignancies has a status update. The study is temporarily n…