Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) [Phase 2]
Phase 2 trial update of decitabine with or without valproic acid in myelodysplastic syndrome and acute myelogenous leukemia; completed with …
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: 5-Azacytidine Prior to Allogeneic Stem Cell Transplant in High Risk Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluating azacitidine given before allogeneic stem cell transplantation in high-risk myelodysplastic syndrome has completed…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Vorinostat in Combination With Azacitidine in Patients With Newly-Diagnosed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial evaluating vorinostat in combination with azacitidine in newly diagnosed AML or MDS; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia [Phase 1, Phase 2]
A Phase I/II study evaluating the combination of MGCD0103 with azacitidine in high-risk myelodysplastic syndrome or acute myeloid leukemia h…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, and biological activity of oral clioquinol in patients with relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2015-06-18Clinical Trial Update: A Study of Lenalidomide Versus Placebo in Subjects With Transfusion Dependent Anemia in Lower Risk Myelodysplastic Syndrome (MDS) Without Del 5q [Phase 3]
A Phase 3 randomized trial comparing lenalidomide to placebo in transfusion-dependent anemia in lower-risk myelodysplastic syndrome without …
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CLINICAL_TRIALS trial_result · 2015-06-18Clinical Trial Update: Study of LBH589 for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial for LBH589 in patients with low or intermediate-1 risk myelodysplastic syndrome was terminated; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-09Clinical Trial Update: Iron Overload and Transient Elastography in Patients With Myelodysplastic Syndrome
A completed clinical trial evaluating iron overload in patients with myelodysplastic syndrome. The study also used transient elastography to…
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Alloreactive NK Cells for Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 trial evaluating alloreactive NK cells as an adjunct to allogeneic stem cell transplantation in patients with myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Phase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 2]
This Phase 2 trial comparing Vidaza (azacitidine), MGCD0103, and their combination in elderly patients with newly diagnosed acute myeloid le…
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Haplo-identical/Mismatched Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome
A completed clinical trial (NCT01793675) evaluating haplo-identical/mismatched hematopoietic stem cell transplantation for patients with adv…
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia [Phase 1]
This Phase 1 trial update reports on the use of sorafenib in patients with refractory or relapsed acute leukemia, myelodysplastic syndromes,…
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CLINICAL_TRIALS research · 2015-04-24Clinical Trial Update: A Study of the Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q [Phase 2]
This is a Phase 2 clinical trial evaluating lenalidomide combined with escalating-dose chemotherapy for intermediate-2 or high-risk myelodys…
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML [Phase 1]
Phase 1 trial evaluating allogeneic stem cell transplantation in high-risk CD33+ acute myeloid leukemia, myelodysplastic syndrome, and juven…
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants [Phase 2]
A Phase 2 clinical trial evaluating a sirolimus-tacrolimus combination following HLA-matched related peripheral blood stem cell transplantat…
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Efficacy and Tolerability of the Combination of Valproic Acid and Lenalidomide in the Treatment of Patients With Myelodysplastic Syndrome [Phase 2]
A Phase 2 study evaluating the combination of valproic acid and lenalidomide for myelodysplastic syndrome has been terminated; the update di…
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Haploid Allogeneic Transplant Using the CliniMACS System [Phase 2]
A Phase 2 clinical trial evaluating haploid allogeneic transplantation using the CliniMACS System was terminated, with results posted in 201…
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Phase II Study of Idarubicin, Cytarabine, and Vorinostat With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) [Phase 2]
Phase II clinical trial evaluating a combination of idarubicin, cytarabine, and vorinostat in high-risk myelodysplastic syndrome and acute m…
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CLINICAL_TRIALS trial_result · 2015-03-04Clinical Trial Update: A Clinical Study of KRN321 in Adult Subjects With Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial of KRN321 in adults with myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2015-02-26Clinical Trial Update: Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies [Phase 1]
Phase 1 trial of Actinium-225-labeled HuM195 (lintuzumab) for advanced myeloid malignancies has completed.
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FDA approval · 2015-02-23FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for Vidaza (azacitidine) submitted by Celgene Corporation.
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CLINICAL_TRIALS trial_result · 2015-02-13Clinical Trial Update: Temsirolimus in Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 clinical trial evaluating temsirolimus for myelodysplastic syndrome has been terminated.
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CLINICAL_TRIALS trial_result · 2015-02-12Clinical Trial Update: Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT [Phase 2]
Phase 2 clinical trial evaluating reduced intensity total body irradiation plus Thymoglobulin followed by allogeneic peripheral blood stem c…
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CLINICAL_TRIALS trial_result · 2015-02-10Clinical Trial Update: Safety and Efficacy Study of AS101 to Treat Elderly Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients [Phase 2]
A Phase 2 safety and efficacy study of AS101 for elderly patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome has been suspende…
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CLINICAL_TRIALS trial_result · 2015-01-28Clinical Trial Update: Bioequivalence Study of Azacitidine for Injection in Myelodysplastic Syndrome (MDS) Patients [Phase 1]
Phase 1 bioequivalence study of azacitidine for injection in myelodysplastic syndrome patients has completed.