Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study Investigating Patient-Reported Outcomes in Lower-risk MDS Patients
The study evaluating patient-reported outcomes in lower-risk myelodysplastic syndrome patients is currently active but not recruiting. Spons…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms [Phase 1]
Phase 1 study evaluating FLAG-Ida chemotherapy plus pivekimab sunirine (IMGN632) for newly diagnosed adverse-risk acute myeloid leukemia and…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: ONC201 in Treating Patients With Relapsed or Refractory Acute Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating ONC201 for relapsed or refractory acute lymphoblastic leukemia, relapsed or refractory acute mye…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
Clinical trial update of a Phase 2 study evaluating venetoclax in combination with ASTX727 (oral decitabine/cedazuridine) for chronic myelom…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma [Phase 1]
A Phase 1 clinical trial evaluating the VSV-hIFNβ-NIS vaccine with or without cyclophosphamide and in combination with ipilimumab, nivolumab…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of the combination of vorinostat and azacitidine in patients with myelodysplastic syndr…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia [Phase 2]
Phase II open-label trial evaluating subcutaneous canakinumab (anti-IL-1β) for patients with low- to intermediate-1-risk myelodysplastic syn…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy) [Phase 2]
Clinical trial update outlining plans to study IDH1 inhibitor olutasidenib in combination with ASTX727 and venetoclax for acute myeloid leuk…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts [Phase 1]
Phase 1 clinical trial evaluating TAK-243 for relapsed or refractory acute myeloid leukemia and myelodysplastic syndromes with increased bla…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies [Phase 3]
A Phase 3 clinical trial comparing haploidentical hematopoietic stem cell transplantation from young non-first-degree donors versus older fi…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial evaluating BMS-986497 (ORM-6151) as monotherapy and in dual/triple combinations with azacitidine and venetoclax in re…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study [Phase 1, Phase 2]
PedAL BCU, LLC is conducting a pediatric screening trial to test bone marrow and blood methods in children with relapsed or hard-to-treat ac…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies [Phase 1]
Phase 1 safety trial update for SEA-CD70 in myeloid malignancies; the study in myelodysplastic syndrome and acute myeloid leukemia is curren…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Prophylactic and Therapeutic DLI-X for Leukemia Relapse After HCT [Phase 1]
Phase 1 clinical trial update on DLI-X as a prophylactic and therapeutic donor lymphocyte infusion to prevent or treat leukemia relapse afte…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: WearAble Technology for Collecting Health Data in People Who Are the Transfused (WATCH Transfused) - A UK Exploratory Study to Improve Quality of Life and the Efficacy of Transfusion Supportive Care in People With Blood Cancers Undergoing Treatment
An exploratory UK clinical trial sponsored by the University of Oxford is evaluating wearable technology to collect health data in people wi…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study [NA]
Completed clinical trial evaluating a geriatric optimization plan to improve survival in older adults undergoing allogeneic hematopoietic ce…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Seclidemstat and Azacitidine for the Treatment of Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia [Phase 1, Phase 2]
Clinical trial update indicates Seclidemstat in combination with azacitidine is being studied for myelodysplastic syndrome or chronic myelom…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms [Phase 1]
An update on a Phase 1 safety and tolerability study of INCB057643 in myelofibrosis and other advanced myeloid neoplasms, with the trial cur…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: A Study to Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML [Phase 1, Phase 2]
Clinical trial update for S227928 as a single agent and in combination with Venetoclax in relapsed/refractory AML, MDS/AML, and CMML shows t…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 salvage chemotherapy trial using cladribine in relapsed/refractory and high-risk myeloid diseases (acute myeloid leukemia and myel…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating a multi-agent regimen of fludarabine phosphate, cytarabine, filgrastim-sndz, gemtuzumab ozogamicin, and idarubicin …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating CMV-MVA Triplex Vaccine to enhance CMV-specific immunity and prevent CMV viremia in patients undergoing ha…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF) [Phase 1]
CERo Therapeutics is conducting a Phase 1 trial of CER-1236 for acute myeloid leukemia, myelodysplastic syndrome, and myelofibrosis; the stu…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms
This clinical trial update discusses a study of acquired pyruvate kinase deficiency in clonal myeloid neoplasms. The trial is currently acti…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS [Phase 1]
Phase 1 clinical trial update evaluating the combination of everolimus (RAD001) with midostaurin (PKC412) in relapsed, refractory, or poor-p…