Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: INCB018424 in Patients With Advanced Hematologic Malignancies [Phase 2]
Phase 2 trial of INCB018424 (ruxolitinib) in patients with advanced hematologic malignancies. Results for diseases including AML, ALL, MDS, …
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: Eltrombopag With or Without Hypomethylating Agent After Hypomethylating Agent Failure For Patients With Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 clinical trial evaluating eltrombopag with or without a hypomethylating agent after hypomethylating agent failure in patients with m…
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CLINICAL_TRIALS trial_result · 2020-01-30Clinical Trial Update: Study of the Safety and Efficacy of APR-246 in Combination With Azacitidine [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating APR-246 in combination with azacitidine for myelodysplastic syndrome with gene mutation and acute myeloid l…
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts [Phase 2]
A Phase 2 clinical trial evaluating T cell depletion in recipients of HLA haploidentical related donor stem cell grafts for various hematolo…
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Controlled Study of Post-transplant Azacitidine for Prevention of Acute Myelogenous Leukemia and Myelodysplastic Syndrome Relapse (VZ-AML-PI-0129) [Phase 3]
Phase 3 clinical trial evaluating post-transplant azacitidine to prevent relapse in acute myeloid leukemia and myelodysplastic syndrome; tri…
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Erlotinib Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating erlotinib hydrochloride in relapsed or refractory acute myeloid leukemia has completed with posted results…
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CLINICAL_TRIALS trial_result · 2020-01-06Clinical Trial Update: Sorafenib Plus 5-Azacitidine Initial Therapy of Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MS) With FLT3-ITD Mutation [Phase 2]
Phase 2 trial evaluating sorafenib in combination with 5-azacitidine as initial therapy for AML and high-risk MDS with FLT3-ITD mutation; tr…
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Eltrombopag With Decitabine in Advanced Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial of eltrombopag with decitabine in advanced myelodysplastic syndrome has been terminated; results posted.
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FDA approval · 2019-12-30FDA Approved: DEFERASIROX — Original Application (Xiromed, LLC)
FDA approved Xiromed, LLC's generic deferasirox (DEFERASIROX) through an original ANDA.
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CLINICAL_TRIALS trial_result · 2019-12-20Clinical Trial Update: Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating total-body irradiation and fludarabine phosphate followed by donor peripheral blood stem cell transpla…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults [Phase 2]
Phase 2 trial investigating an immunosuppressive regimen followed by blood cell transplant for treating blood cancers in older adults; compl…
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: NK Cell Based Non-Myeloablative Transplantation in Acute Myeloid Diseases [Phase 2]
Phase 2 trial update on NK cell–based non-myeloablative transplantation for acute myeloid diseases, including acute myeloid leukemia and mye…
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections [Phase 4]
Phase 4 clinical trial update reporting pharmacokinetics of posaconazole (Noxafil) when used as prophylaxis for invasive fungal infections i…
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CLINICAL_TRIALS trial_result · 2019-12-10Clinical Trial Update: Azacytidine and Lymphocytes in Relapse of AML or MDS After Allogeneic Stem Cell Transplantation. [Phase 2]
Phase 2 clinical trial evaluating azacytidine and lymphocytes in relapse of acute myeloid leukemia or myelodysplastic syndrome after allogen…
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FDA approval · 2019-11-20FDA Approved: DEFERASIROX — Original Application (Dr. Reddy's Laboratories Inc)
FDA approved Dr. Reddy's Laboratories' original application for deferasirox, a generic iron chelator used to treat chronic iron overload in …
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CLINICAL_TRIALS trial_result · 2019-11-19Clinical Trial Update: Efficacy and Safety of Lenalidomide in Combination With Cyclosporine A in Patients With Myelodysplastic Syndromes [Phase 2]
Phase 2 trial evaluating lenalidomide with cyclosporine A in patients with myelodysplastic syndromes; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Feasibility and Outcomes of Allogeneic HCT Compared to Chemotherapy in Older AML Patients
A completed clinical trial comparing allogeneic hematopoietic cell transplantation to chemotherapy in older AML patients, with results poste…
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CLINICAL_TRIALS trial_result · 2019-11-08Clinical Trial Update: Study of the Safety and Efficacy of CC-5013 Treatment For Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial update for CC-5013 in myelodysplastic syndrome assessing safety and efficacy.
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CLINICAL_TRIALS trial_result · 2019-10-21Clinical Trial Update: Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia [Phase 2]
Phase 2 clinical trial assessing management of platelet transfusion therapy in patients with blood cancers or treatment-induced thrombocytop…
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CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: A Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Cancer Indications [Phase 1, Phase 2]
A dose-escalation Phase I study is evaluating safety and preliminary activity of a multi-indication cancer therapy in acute myeloid leukemia…
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FDA approval · 2019-09-09FDA Approved: AZACITIDINE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
The FDA approved a supplemental application for azacitidine from Dr. Reddy's Laboratories Inc. (ANDA201537).
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating the WEE1 inhibitor AZD1775 with or without cytarabine in advanced acute myeloid leukemia or myelodysplastic syndrom…
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CLINICAL_TRIALS research · 2019-09-06Clinical Trial Update: Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Clinical trial assessing electrophysiological biomarkers of chemotherapy-related cognitive impairment and recovery; study completed with pos…
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CLINICAL_TRIALS trial_result · 2019-07-11Clinical Trial Update: Study With Azacitidine in Pediatric Subjects With Newly Diagnosed Advanced Myelodysplastic Syndrome (MDS) and Juvenile Myelomonocytic Leukemia (JMML) [Phase 2]
A Phase 2 clinical trial evaluating azacitidine in pediatric patients with newly diagnosed advanced myelodysplastic syndrome and juvenile my…