Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-07-30Clinical Trial Update: Clinical Phase III Trial Treosulfan-based Conditioning Versus Reduced-intensity Conditioning (RIC) [Phase 3]
Phase III trial comparing treosulfan-based conditioning to reduced-intensity conditioning in acute myeloid leukemia and myelodysplastic synd…
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CLINICAL_TRIALS trial_result · 2020-07-01Clinical Trial Update: Deferasirox in Treating Patients With Very Low, Low, or Intermediate-Risk Red Blood Cell Transfusion Dependent Anemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating deferasirox for very low/low/intermediate-risk transfusion-dependent anemia and myelodysplastic syndrome was termin…
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Preventing Stem Cell Transplant Complications With a Blood Separator Machine [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating a blood separator machine to prevent complications after stem cell transplant.
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status [Phase 1]
Phase I study of AC220 (trastuz? actually AC220 is quizartinib, a FLT3 inhibitor) in relapsed/refractory AML regardless of FLT3 status; comp…
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CLINICAL_TRIALS trial_result · 2020-04-21Clinical Trial Update: Donor-Derived Humoral Immunity, Hematopoietic Stem Cell Transplantation, TAR [NA]
Clinical trial update on donor-derived humoral immunity and hematopoietic stem cell transplantation completed with posted results in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-27Clinical Trial Update: A Randomized Trial of rhTPO Versus Placebo for Low/Intermediate-1 Risk MDS With Thrombocytopenia [Phase 2, Phase 3]
A randomized trial compares rhTPO to placebo for thrombocytopenia in patients with Low/Intermediate-1 risk myelodysplastic syndrome (MDS). P…
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating decitabine with the GCLAM regimen in adults with newly diagnosed, relapsed, or refractory acute myeloi…
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CLINICAL_TRIALS trial_result · 2020-02-26Clinical Trial Update: The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS) [Phase 3]
A Phase 3 trial assessed oral azacitidine plus best supportive care versus placebo and best supportive care in transfusion-dependent, low-ri…
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CLINICAL_TRIALS trial_result · 2020-02-24Clinical Trial Update: Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 trial comparing CIA versus FLAI in acute myeloid leukemia and high-risk myelodysplastic syndrome completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: INCB018424 in Patients With Advanced Hematologic Malignancies [Phase 2]
Phase 2 trial of INCB018424 (ruxolitinib) in patients with advanced hematologic malignancies. Results for diseases including AML, ALL, MDS, …
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: Eltrombopag With or Without Hypomethylating Agent After Hypomethylating Agent Failure For Patients With Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 clinical trial evaluating eltrombopag with or without a hypomethylating agent after hypomethylating agent failure in patients with m…
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CLINICAL_TRIALS trial_result · 2020-01-30Clinical Trial Update: Study of the Safety and Efficacy of APR-246 in Combination With Azacitidine [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating APR-246 in combination with azacitidine for myelodysplastic syndrome with gene mutation and acute myeloid l…
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts [Phase 2]
A Phase 2 clinical trial evaluating T cell depletion in recipients of HLA haploidentical related donor stem cell grafts for various hematolo…
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Controlled Study of Post-transplant Azacitidine for Prevention of Acute Myelogenous Leukemia and Myelodysplastic Syndrome Relapse (VZ-AML-PI-0129) [Phase 3]
Phase 3 clinical trial evaluating post-transplant azacitidine to prevent relapse in acute myeloid leukemia and myelodysplastic syndrome; tri…
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Erlotinib Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating erlotinib hydrochloride in relapsed or refractory acute myeloid leukemia has completed with posted results…
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CLINICAL_TRIALS trial_result · 2020-01-06Clinical Trial Update: Sorafenib Plus 5-Azacitidine Initial Therapy of Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MS) With FLT3-ITD Mutation [Phase 2]
Phase 2 trial evaluating sorafenib in combination with 5-azacitidine as initial therapy for AML and high-risk MDS with FLT3-ITD mutation; tr…
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Eltrombopag With Decitabine in Advanced Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial of eltrombopag with decitabine in advanced myelodysplastic syndrome has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2019-12-20Clinical Trial Update: Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating total-body irradiation and fludarabine phosphate followed by donor peripheral blood stem cell transpla…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults [Phase 2]
Phase 2 trial investigating an immunosuppressive regimen followed by blood cell transplant for treating blood cancers in older adults; compl…
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: NK Cell Based Non-Myeloablative Transplantation in Acute Myeloid Diseases [Phase 2]
Phase 2 trial update on NK cell–based non-myeloablative transplantation for acute myeloid diseases, including acute myeloid leukemia and mye…
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections [Phase 4]
Phase 4 clinical trial update reporting pharmacokinetics of posaconazole (Noxafil) when used as prophylaxis for invasive fungal infections i…
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CLINICAL_TRIALS trial_result · 2019-12-10Clinical Trial Update: Azacytidine and Lymphocytes in Relapse of AML or MDS After Allogeneic Stem Cell Transplantation. [Phase 2]
Phase 2 clinical trial evaluating azacytidine and lymphocytes in relapse of acute myeloid leukemia or myelodysplastic syndrome after allogen…
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CLINICAL_TRIALS trial_result · 2019-11-19Clinical Trial Update: Efficacy and Safety of Lenalidomide in Combination With Cyclosporine A in Patients With Myelodysplastic Syndromes [Phase 2]
Phase 2 trial evaluating lenalidomide with cyclosporine A in patients with myelodysplastic syndromes; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Feasibility and Outcomes of Allogeneic HCT Compared to Chemotherapy in Older AML Patients
A completed clinical trial comparing allogeneic hematopoietic cell transplantation to chemotherapy in older AML patients, with results poste…
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CLINICAL_TRIALS trial_result · 2019-11-08Clinical Trial Update: Study of the Safety and Efficacy of CC-5013 Treatment For Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial update for CC-5013 in myelodysplastic syndrome assessing safety and efficacy.