Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: DEPLETHINK - LymphoDEPLEtion and THerapeutic Immunotherapy With NKR-2 [Phase 1, Phase 2]
Clinical trial update for DEPLETHINK (NKR-2) reporting Phase 1/Phase 2 results in AML and MDS; trial status completed.
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CLINICAL_TRIALS trial_result · 2021-04-26Clinical Trial Update: Vidaza and Valproic Acid Post Allogeneic Transplant for High Risk AML and MDS [Phase 2]
Phase 2 clinical trial evaluating Vidaza (azacitidine) and valproic acid after allogeneic transplant in high-risk AML and MDS.
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CLINICAL_TRIALS trial_result · 2021-04-13Clinical Trial Update: Busulfan and Cyclophosphamide Followed By ALLO BMT [NA]
Clinical trial update for busulfan and cyclophosphamide followed by allogeneic stem cell transplant in acute leukemias; study is terminated …
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: Early Palliative Care for Patients With Haematological Malignancies [Phase 3]
Phase 3 clinical trial update on early palliative care for patients with hematologic malignancies including acute myeloid leukemia and myelo…
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CLINICAL_TRIALS trial_result · 2021-03-22Clinical Trial Update: Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms [Phase 2]
Phase 2 trial evaluating early allogeneic hematopoietic cell transplantation for patients with relapsed or refractory high-grade myeloid neo…
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CLINICAL_TRIALS trial_result · 2021-03-18Clinical Trial Update: The Rapid Study: Randomized Phase II Study To Expedite Allogeneic Transplant With Immediate Haploidentical Plus Unrelated Cord Donor Search Versus Matched Unrelated Donor Search For AML And High-Risk MDS Patients [Phase 2]
Phase II randomized trial evaluating rapid haploidentical plus unrelated cord donor search versus matched unrelated donor search for AML and…
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patients [Phase 1]
A Phase 1 trial evaluating the combination of glasdegib (PF-04449913) with azacitidine in untreated myelodysplastic syndrome, acute myeloid …
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CLINICAL_TRIALS trial_result · 2021-02-26Clinical Trial Update: Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating treosulfan, fludarabine phosphate, and total-body irradiation as conditioning before donor stem cell transplant in …
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms [Phase 1, Phase 2]
Phase 1b/2 trial assessing APR-246 plus azacitidine in TP53-mutant myeloid neoplasms completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Busulfan, Fludarabine, Clofarabine With Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating busulfan, fludarabine, and clofarabine conditioning followed by allogeneic stem cell transplantation in pa…
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: IV Busulfan With Allo-BMT: Study for Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome [Phase 3]
Phase 3 trial evaluating intravenous busulfan with allogeneic hematopoietic stem cell transplant for patients with myelodysplastic syndrome …
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for RAEB-1,REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT [Phase 2, Phase 3]
A Phase 2/Phase 3 trial compares G-CSF+DAC+BUCY versus G-CSF+DAC+BF conditioning regimens for RAEB-1/REAB-2 and AML secondary to MDS in pati…
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor [Phase 2, Phase 3]
Clinical trial update on ATIR donor lymphocyte preparation for haploidentical stem cell transplantation; study terminated with posted result…
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor [Phase 2]
Phase 2 trial evaluating two doses of ATIR101 (T-lymphocyte enriched, host alloreactive T-cell depleted) in hematologic malignancy patients …
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Safety and Efficacy of Donor T-lymphocytes Depleted ex Vivo of Host Alloreactive T-cells (ATIR) in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor [Phase 2]
Phase 2 trial update on ATIR, donor T-lymphocytes depleted ex vivo of host alloreactive T-cells, in patients with hematologic malignancies p…
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CLINICAL_TRIALS trial_result · 2020-12-24Clinical Trial Update: Decitabine Versus Azacitidine in Myelodysplastic Syndrome Patients With Low and Intermediate-1 Risk [Phase 2]
Phase 2 trial comparing decitabine to azacitidine in myelodysplastic syndrome patients with low and intermediate-1 risk; results completed w…
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Pharmacokinetics of Anidulafungin (Ecalta ®) Intravenous Given to Patients at High Risk for Developing Invasive Fungal Disease [Phase 2]
Phase 2 pharmacokinetics study of intravenous anidulafungin (Ecalta) in patients at high risk for invasive fungal disease has been completed…
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Pharmacokinetics of Micafungin Given Twice Weekly Intravenously Compared to Micafungin Given Daily to Patients at Risk for Developing an Invasive Fungal Disease [Phase 2]
Phase 2 trial update comparing twice-weekly intravenous micafungin pharmacokinetics to daily dosing in patients at risk for invasive fungal …
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Clofarabine Combinations in Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS) and Myeloid Blast Phase Chronic Myeloid Leukemia (CML) [Phase 2]
Phase 2 trial update of clo farabine combinations in relapsed/refractory AML and MDS (and myeloid blast phase CML) with results posted.
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CLINICAL_TRIALS trial_result · 2020-10-27Clinical Trial Update: Combined Haploidentical-Cord Blood Transplantation for Adults and Children [NA]
Clinical trial update on combined haploidentical-cord blood transplantation in adults and children for leukemia and myelodysplastic syndrome…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase Inhibitor (CDAi) in Patients With Myelodysplastic Syndromes (MDS) [Phase 1, Phase 2]
Phase 1/2 trial evaluating pharmacokinetic guided dose escalation and confirmation using oral decitabine with the oral cytidine deaminase in…
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating donor lymphocyte infusion with azacitidine to prevent relapse after stem cell transplantation.
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CLINICAL_TRIALS trial_result · 2020-09-21Clinical Trial Update: Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM [Phase 1, Phase 2]
Phase 1/2 clinical trial update for NiCord (umbilical cord blood-derived ex vivo expanded cells) in hematological malignancies, including AL…
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating a stem cell transplant using peripheral and cord blood stem cells for severe aplastic anemia and myelodysp…
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: INSPIRE: Internet and Social-media Program With Information and Resources for Long-Term Cancer Survivors Who Underwent Stem Cell Transplant [Phase 3]
Phase 3 clinical trial update for INSPIRE program addressing information/resources for long-term cancer survivors who underwent stem cell tr…