Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: G-CSF+Decitabine+BUCY vs BUCY Conditioning Regimen for RAEB-1, REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT [Phase 2, Phase 3]
Clinical trial comparing G-CSF plus Decitabine with BU-CY conditioning versus BU-CY alone for RAEB-1/RAEB-2 and AML secondary to MDS in allo…
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CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A phase 1/2 trial evaluating vosaroxin with decitabine in older adults with acute myeloid leukemia and high-risk myelodysplastic syndrome ha…
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CLINICAL_TRIALS trial_result · 2021-12-28Clinical Trial Update: Intensified Azacitidine in High Risk Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
A clinical trial update reports on intensified azacitidine regimens in high-risk myelodysplastic syndrome, across Phase 1 and Phase 2, with …
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CLINICAL_TRIALS trial_result · 2021-12-16Clinical Trial Update: Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) [Phase 3]
Phase 3 trial evaluating fludarabine-IV busulfan with or without clofarabine as conditioning for allogeneic hematopoietic stem cell transpla…
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CLINICAL_TRIALS trial_result · 2021-11-19Clinical Trial Update: Randomized Phase III Study of Decitabine +/- Hydroxyurea (HY) Versus HY in Advanced Proliferative CMML [Phase 3]
Phase III randomized trial investigating decitabine with or without hydroxyurea versus hydroxyurea alone in advanced proliferative CMML/MDS-…
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CLINICAL_TRIALS trial_result · 2021-11-15Clinical Trial Update: Treatment of Patients With Myelodysplastic Syndrome or Acute Myelocytic Leukemia With an Impending Hematological Relapse With Azacitidine (Vidaza) [Phase 2]
Phase 2 trial investigating azacitidine (Vidaza) for patients with myelodysplastic syndrome or acute myeloid leukemia at impending hematolog…
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CLINICAL_TRIALS trial_result · 2021-10-11Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 trial evaluating milademetan alone and with 5-azacitidine in acute myeloid leukemia or high-risk myelodysplastic syndrome; study ter…
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CLINICAL_TRIALS trial_result · 2021-10-07Clinical Trial Update: Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial evaluating idarubicin, cytarabine, and nivolumab in high-risk myelodysplastic syndrome and acute myeloid leukemia; study com…
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CLINICAL_TRIALS trial_result · 2021-10-01Clinical Trial Update: Azacitidine and Pembrolizumab in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial investigating azacitidine combined with pembrolizumab for high-risk myelodysplastic syndrome (IPSS intermediate-1).
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CLINICAL_TRIALS trial_result · 2021-10-01Clinical Trial Update: A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Max-40279-01 in Combination With Azacitidine (AZA) in Patients With Myelodysplastic Syndrome (MDS) or Relapsed/Refractory Acute Myeloid Leukemia (R/R AML) [Phase 1, Phase 2]
Phase 1/2 trial investigating Max-40279-01 with azacitidine for myelodysplastic syndrome and relapsed/refractory acute myeloid leukemia; saf…
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Isavuconazole in Preventing Invasive Fungal Infections in Adult Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome and Neutropenia [Phase 2]
Phase 2 trial evaluating isavuconazole for preventing invasive fungal infections in adults with newly diagnosed acute myeloid leukemia or my…
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Hetrombopag for Low/Intermediate-1 Risk MDS With Thrombocytopenia [Phase 2, Phase 3]
A Phase 2/Phase 3 trial update for Hetrombopag in low/intermediate-1 risk myelodysplastic syndrome with thrombocytopenia is ongoing with unk…
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CLINICAL_TRIALS trial_result · 2021-09-02Clinical Trial Update: Nonmyeloablative Haploidentical Transplant Followed by MLN9708 [Phase 2]
Phase 2 trial evaluating nonmyeloablative haploidentical transplant followed by MLN9708 (ixazomib) in various hematologic malignancies compl…
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CLINICAL_TRIALS trial_result · 2021-09-02Clinical Trial Update: Phase II Study of Azacitidine and Sargramostim as Maintenance Treatment for Poor-Risk AML or MDS [Phase 2]
Phase II study evaluating azacitidine with sargramostim as maintenance therapy for poor-risk AML or MDS has completed; results posted in 202…
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: Study of Deferasirox for Treatment of Transfusional Iron Overload in Myelodysplastic Patients [Phase 2]
Phase 2 clinical trial evaluating deferasirox for treating transfusional iron overload in patients with myelodysplastic syndrome has complet…
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CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: Revlimid in Transfusion Dependent Patients [Phase 2]
Phase 2 results for lenalidomide (Revlimid) in transfusion-dependent myelodysplastic syndrome patients have been completed, with results pos…
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CLINICAL_TRIALS trial_result · 2021-07-12Clinical Trial Update: A Trial of Pembrolizumab (MK-3475) in Participants With Blood Cancers (MK-3475-013/KEYNOTE-013) [Phase 1]
Phase 1 trial evaluating pembrolizumab (MK-3475) in blood cancers has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-08Clinical Trial Update: Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia [Phase 3]
Phase 3 clinical trial evaluating lenalidomide with or without epoetin alfa for myelodysplastic syndrome and associated anemia, with results…
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CLINICAL_TRIALS trial_result · 2021-07-06Clinical Trial Update: Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes [Phase 2]
Phase 2 trial evaluating donor umbilical cord blood transplant with or without ex-vivo expanded cord blood progenitor cells in patients with…
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma [Phase 2]
Phase 2 trial evaluating CD8+ memory T-cells as consolidative therapy after donor non-myeloablative hematopoietic cell transplant in leukemi…
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Phase II Part 2 Expansion of Oral Rigosertib in Combination With Azacitidine [Phase 1, Phase 2]
Phase II extension study of oral rigosertib in combination with azacitidine in myelodysplastic syndrome and related conditions has completed…
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CLINICAL_TRIALS trial_result · 2021-06-09Clinical Trial Update: Omacetaxine in Patients With Intermediate-1 and Higher Risk Myelodysplastic Syndrome (MDS) Post Hypomethylating Agent (HMA) Failure [Phase 2]
Phase 2 trial evaluating omacetaxine in intermediate-1 and higher risk myelodysplastic syndrome after failure of hypomethylating therapy; st…
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CLINICAL_TRIALS trial_result · 2021-06-08Clinical Trial Update: Unrelated Umbilical Cord Blood (UBC)Transplantation [NA]
Clinical trial update for unrelated umbilical cord blood transplantation; the study is completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-05-19Clinical Trial Update: Leukemia SPORE Phase II DAC Study for R/R and Elderly Acute AML and MDS [Phase 2]
Phase II trial update for DAC in relapsed/refractory and elderly patients with acute myeloid leukemia and myelodysplastic syndrome.
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: A Phase I-II Open Label Non-Randomized Study Using TL32711 for Patients With Acute Myelogenous Leukemia, Myelodysplastic Syndrome and Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase I-II open-label trial of TL32711 in acute myeloid leukemia, myelodysplastic syndrome, and acute lymphoblastic leukemia; study terminat…