Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Total Body Irradiation/Fludarabine Based Ablative Haploidentical Transplant for Hematologic Diseases [Phase 2]
Phase 2 trial evaluating total body irradiation with fludarabine-based conditioning followed by haploidentical transplantation for hematolog…
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) [Phase 3]
Phase 3 clinical trial comparing single versus double umbilical cord blood transplants in children with high-risk leukemia and myelodysplasi…
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy
A completed clinical trial update assessing structural brain imaging and cognitive function in adult stem cell transplant recipients treated…
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Treosulfan-based Conditioning for Transplantation in AML/MDS [Phase 2]
Phase 2 trial evaluating treosulfan-based conditioning for transplantation in acute myeloid leukemia and myelodysplastic syndrome. The study…
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Clinical Ex Vivo Expansion of Human Umbilical Cord Blood Stem and Progenitor Cells [Phase 1, Phase 2]
An update on a Phase 1/2 trial evaluating ex vivo expansion of human umbilical cord blood stem and progenitor cells for patients with acute …
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Dose Finding Study of Post-BMT Decitabine Maintenance Treatment in Higher-risk MDS and MDS/AML [Phase 1]
Phase 1 dose-finding study evaluating decitabine maintenance after bone marrow transplant in higher-risk myelodysplastic syndrome and MDS/AM…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: 5 Day Versus 7 Day Azacitidine in Lower Risk Myelodysplastic Syndrome [Phase 2]
This clinical trial update reports on a Phase 2 study comparing 5-day versus 7-day azacitidine in lower-risk myelodysplastic syndrome. The c…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Study of KB004 in Subjects With Hematologic Malignancies (Myelodysplastic Syndrome, MDS, Myelofibrosis, MF) [Phase 1, Phase 2]
A Phase 1/2 study of KB004 in myelodysplastic syndrome and myelofibrosis, sponsored by Humanigen, Inc., is currently suspended.
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CLINICAL_TRIALS trial_result · 2015-11-13Clinical Trial Update: Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating a triple regimen of vorinostat, tacrolimus, and methotrexate to prevent graft-versus-host disease after allogeneic …
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CLINICAL_TRIALS trial_result · 2015-11-05Clinical Trial Update: Clinical Study of PM01183 in Patients With Acute Leukemia or Relapsed/Refractory Myelodysplastic Syndrome [Phase 1]
Phase 1 study of PM01183 (lurbinectedin) in patients with acute leukemia and relapsed/refractory myelodysplastic syndrome has completed enro…
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CLINICAL_TRIALS trial_result · 2015-10-28Clinical Trial Update: A Clinical Trial of Decitabine in Patients With Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial of decitabine in patients with myelodysplastic syndrome has been terminated.
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CLINICAL_TRIALS trial_result · 2015-10-06Clinical Trial Update: Transplant-Related Mortality in Patients Undergoing a Peripheral Blood Stem Cell Transplantation or an Umbilical Cord Blood Transplantation
This is an update on a completed trial assessing transplant-related mortality in patients undergoing peripheral blood stem cell transplantat…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Outpatient Platelet Transfusions in Myelodysplastic Syndromes and Leukemia: The OPTIMAL Pilot [NA]
A pilot trial (OPTIMAL) evaluating outpatient platelet transfusions in patients with myelodysplastic syndromes and leukemia was terminated.
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) [Phase 2]
Phase 2 trial update of decitabine with or without valproic acid in myelodysplastic syndrome and acute myelogenous leukemia; completed with …
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: 5-Azacytidine Prior to Allogeneic Stem Cell Transplant in High Risk Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluating azacitidine given before allogeneic stem cell transplantation in high-risk myelodysplastic syndrome has completed…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Vorinostat in Combination With Azacitidine in Patients With Newly-Diagnosed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial evaluating vorinostat in combination with azacitidine in newly diagnosed AML or MDS; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia [Phase 1, Phase 2]
A Phase I/II study evaluating the combination of MGCD0103 with azacitidine in high-risk myelodysplastic syndrome or acute myeloid leukemia h…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, and biological activity of oral clioquinol in patients with relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2015-06-18Clinical Trial Update: A Study of Lenalidomide Versus Placebo in Subjects With Transfusion Dependent Anemia in Lower Risk Myelodysplastic Syndrome (MDS) Without Del 5q [Phase 3]
A Phase 3 randomized trial comparing lenalidomide to placebo in transfusion-dependent anemia in lower-risk myelodysplastic syndrome without …
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CLINICAL_TRIALS trial_result · 2015-06-18Clinical Trial Update: Study of LBH589 for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial for LBH589 in patients with low or intermediate-1 risk myelodysplastic syndrome was terminated; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-09Clinical Trial Update: Iron Overload and Transient Elastography in Patients With Myelodysplastic Syndrome
A completed clinical trial evaluating iron overload in patients with myelodysplastic syndrome. The study also used transient elastography to…
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Alloreactive NK Cells for Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 trial evaluating alloreactive NK cells as an adjunct to allogeneic stem cell transplantation in patients with myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Phase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 2]
This Phase 2 trial comparing Vidaza (azacitidine), MGCD0103, and their combination in elderly patients with newly diagnosed acute myeloid le…
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Haplo-identical/Mismatched Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome
A completed clinical trial (NCT01793675) evaluating haplo-identical/mismatched hematopoietic stem cell transplantation for patients with adv…
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia [Phase 1]
This Phase 1 trial update reports on the use of sorafenib in patients with refractory or relapsed acute leukemia, myelodysplastic syndromes,…