Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-08-24Clinical Trial Update: APG101 in Myelodysplastic Syndrome [Phase 1]
APG101, an investigational therapy, was studied in a Phase 1 trial for myelodysplastic syndrome; the study has completed.
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase I trial evaluating a combination of midostaurin and bortezomib with chemotherapy in relapsed/refractory acute myeloid leukemia has c…
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CLINICAL_TRIALS trial_result · 2016-06-15Clinical Trial Update: SB1518 for Patients With Myelodysplastic Syndrome (MDS) [Phase 2]
This update reports Phase 2 results for SB1518 in patients with myelodysplastic syndrome (MDS); the trial was terminated and results were po…
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: A Three-part Study of Eltrombopag in Thrombocytopenic Subjects With Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 2]
Eltrombopag was investigated in a Phase 2 study of thrombocytopenic patients with myelodysplastic syndromes or acute myeloid leukemia. The r…
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Safety and Tolerability of Oral Clofarabine in Intermediate to High Risk Myelodysplastic Patients [Phase 1]
Phase 1 trial assessing the safety and tolerability of oral clofarabine in intermediate to high-risk myelodysplastic syndrome; the study sta…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Extended Platelet Parameters as a Means to Differentiate Immune Thrombocytopenia From Hypo-proliferative Thrombocytopenias.
This completed clinical trial from Beth Israel Medical Center evaluated whether extended platelet parameters can distinguish immune thromboc…
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Phase I Study of Sequential Cord Blood Transplants [Phase 1]
Phase I study of sequential cord blood transplants has completed enrollment for conditions including lymphoma, leukemia, multiple myeloma, a…
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Phase 1 Study of TG02 Citrate in Patients With Advanced Hematological Malignancies [Phase 1]
Phase 1 study evaluating TG02 Citrate in patients with advanced hematologic malignancies has completed, including AML, ALL, blast crisis, MD…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies [Phase 2]
Phase 2 clinical trial update on mismatched family member donor stem cell transplantation in children and young adults with high-risk hemato…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation [Phase 2]
Phase 2 clinical trial evaluating repeat transplantation for relapsed or refractory hematologic malignancies after prior transplant; the stu…
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CLINICAL_TRIALS trial_result · 2016-04-21Clinical Trial Update: Birinapant With 5-azacitidine in MDS Subjects Who Are Naïve, Have Relapsed or Are Refractory to 5-azacitidine Therapy [Phase 1, Phase 2]
Completed Phase 1/2 clinical trial evaluating birinapant in combination with azacitidine for patients with myelodysplastic syndrome.
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Phase I Study of an Oncofetal Antigen Multi-Peptide Immunotherapy in Subjects With Hematologic Cancer [Phase 1]
A Phase I clinical trial is evaluating an oncofetal antigen multi-peptide immunotherapy in hematologic cancers, including acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: Belinostat and Bortezomib in Treating Patients With Relapsed or Refractory Acute Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 trial testing belinostat and bortezomib in relapsed or refractory acute leukemias and myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2016-03-28Clinical Trial Update: Idarubicin + Cytarabine and Lenalidomide in Patients With Myelodysplastic Syndrome (MDS), Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial examining idarubicin + cytarabine with lenalidomide for myelodysplastic syndrome and acute myeloid leukemia has completed wi…
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CLINICAL_TRIALS trial_result · 2016-03-22Clinical Trial Update: Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia [Phase 2]
A Phase 2 trial investigates adding lenalidomide or vorinostat to azacitidine in higher-risk myelodysplastic syndromes or chronic myelomonoc…
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: Phase I Clinical Study of CWP232291 in Acute Myeloid Leukemia Patients [Phase 1]
Phase I study of CWP232291 in patients with acute myeloid leukemia and related myeloid neoplasms has completed.
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies [Phase 2]
Phase 2 trial of Brentuximab Vedotin in CD30-positive non-lymphomatous malignancies has completed and results were posted in 2016. The study…
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Study of Azacitidine to Evaluate Safety and Effectiveness for Chinese Patients With Higher Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating azacitidine in Chinese patients with higher-risk myelodysplastic syndrome has completed with posted results.
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Clofarabine Plus Low-Dose Cytarabine Induction and Decitabine Consolidation in Frontline Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial evaluating clofarabine with low-dose cytarabine induction followed by decitabine consolidation in frontline acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety and efficacy of POL6326 for mobilization and transplant in hematologic malignancies has completed…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia [Phase 1]
Phase 1 study of Terameprocol (EM-1421) in leukemia was terminated; no efficacy results were reported in this update.
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Study of Dasatinib and All-Trans Retinoic Acid for Relapsed/Refractory and/or Elderly Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome [Phase 1]
This Phase 1 trial studied the combination of dasatinib and all-trans retinoic acid in relapsed/refractory and/or elderly patients with acut…
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CLINICAL_TRIALS trial_result · 2016-02-01Clinical Trial Update: Rituximab (Rituxan) for the Prevention of EBV-LPD Epstein Barr Virus (EBV) Lymphoproliferative Disorder Post T Cell Depleted Unrelated and HLA Mis-matched Related HSCT [NA]
This trial assessed whether rituximab (Rituxan) can prevent EBV-associated lymphoproliferative disorder after T-cell-depleted unrelated or H…
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Study of Vidaza (Azacitidine) Versus Support Treatment in Patients With Low Risk Myelodysplastic Syndrome (Low and Intermediate-1 IPSS) Without the 5q Deletion and Transfusion Dependent Anaemia [Phase 2]
Phase 2 study comparing azacitidine (Vidaza) to best supportive care in low-risk myelodysplastic syndrome patients without 5q deletion and w…
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Lenalidomide and Prednisone in Low and Int-1 Myelodysplastic Syndrome (MDS) Non 5q MDS [Phase 2]
A Phase 2 clinical trial evaluating lenalidomide with prednisone in low and int-1 risk non-5q myelodysplastic syndrome has completed with re…