Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial evaluated haploidentical allogeneic transplantation with post-transplant regulatory T-cell infusion in…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL) [Phase 2]
A phase 2 trial of alemtuzumab in myelodysplastic syndrome, aplastic anemia, and T-cell large granular lymphocytic leukemia was terminated, …
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Fludarabine and Busulfan Followed by Allogeneic Stem Cell Transplant in Treating Older Patients With Acute Myeloid Leukemia in First Complete Remission [Phase 2]
A Phase 2 trial evaluating conditioning with fludarabine and busulfan followed by allogeneic stem cell transplantation in older adults with …
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs [Phase 2]
A Phase 2 safety and tolerability trial evaluating CDX-301 with or without plerixafor for stem cell mobilization in matched related donor/re…
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Use of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Homing and Subsequent Engraftment [NA]
Clinical trial results posted on using hyperbaric oxygen therapy to improve umbilical cord blood stem cell homing and engraftment in patient…
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CLINICAL_TRIALS trial_result · 2017-03-14Clinical Trial Update: Phase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS) [Phase 2]
Phase II trial of a Hedgehog pathway inhibitor in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) completed with r…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders [Phase 2]
Phase 2 trial evaluating myeloablative conditioning with hyperfractionated total body irradiation plus thiotepa and fludarabine followed by …
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Arsenic Trioxide in Combination With Cytarabine in Patients With High-risk MDS and Poor-prognosis AML [Phase 1, Phase 2]
Phase 1/2 trial evaluating arsenic trioxide in combination with cytarabine for high-risk myelodysplastic syndrome and poor-prognosis acute m…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Phase 2 Study Adding Pracinostat to a Hypomethylating Agent (HMA) in Patients With MDS Who Failed to Respond to Single Agent HMA [Phase 2]
Phase 2 study evaluating adding pracinostat to a hypomethylating agent in patients with myelodysplastic syndrome who did not respond to sing…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant [Phase 2]
Phase 2 trial of T-cell replete haploidentical donor hematopoietic stem cell transplantation with natural killer (NK) cell support in hemato…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Allogeneic Cytokine-induced Killer Immunotherapy for Relapse After Allogeneic Marrow Transplant for Haematological Malignancies [Phase 1, Phase 2]
Phase 1 and Phase 2 results are reported for allogeneic cytokine-induced killer (CIK) cell immunotherapy given to patients who relapsed afte…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders [Phase 1, Phase 2]
A completed Phase 1/2 study from Singapore General Hospital evaluated a Traditional Chinese Medicine formulation for supportive management o…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: 5-Azacytidine With Lenalidomide in Patients With High Risk Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating azacitidine in combination with lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Allogeneic Transplantation From Related Haploidentical Donors [Phase 2]
A Phase 2 clinical trial evaluating allogeneic transplantation from related haploidentical donors for blood cancers and leukemia has complet…
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: Assessment of Body, Liver and Labile Plasma Iron and Their Association With Outcome and Immunological Recovery in Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) Patients Undergoing Allogeneic Stem Cell Transplantation - ALLIVE (ALLogeneic Iron inVEstigators) Observational Trial
An observational study (ALLIVE) completed that evaluated body, liver, and labile plasma iron metrics and their associations with clinical ou…
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: This Study Will Evaluate Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndromes (MDS), Thalassemia and Rare Anemia Types Having Transfusion-induced Iron Overload. [Phase 4]
Phase 4 trial by Novartis evaluated the efficacy and safety of deferasirox in patients with myelodysplastic syndrome, thalassemia, and trans…
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Darbepoetin Alfa in Patients With Anemic Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) [Phase 3]
Phase 3 trial update for darbepoetin alfa in anemic low or intermediate-1 risk myelodysplastic syndrome patients; study completed with resul…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Erlotinib in Higher Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
The Phase 1/2 clinical trial of erlotinib in higher-risk myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2016-10-20Clinical Trial Update: Study of Azacitidine With or Without Birinapant in Subjects With MDS or CMMoL [Phase 2]
Phase 2 study evaluating azacitidine with or without birinapant in patients with Myelodysplastic syndrome or Chronic myelomonocytic leukemia…
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Treosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT [Phase 2]
This Phase 2 trial evaluates a treosulfan/fludarabine/low-dose total body irradiation preparative regimen for children with acute myeloid le…
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CLINICAL_TRIALS trial_result · 2016-10-05Clinical Trial Update: The Effect of Blood Transfusion on Endothelial Function
The completed trial assesses the effect of blood transfusion on endothelial function in patients with myelodysplastic syndrome and anemia.
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CLINICAL_TRIALS trial_result · 2016-09-20Clinical Trial Update: Cytarabine and Daunorubicin With or Without Gemtuzumab Ozogamicin in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 3]
This Phase 3 trial evaluated cytarabine and daunorubicin with or without gemtuzumab ozogamicin in older patients with acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study) [Phase 4]
Phase 4 epidemiological study update evaluating MRI-based assessment of iron overload in patients with thalassemia (including NTDT), myelody…
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Safety and Pharmacokinetics Study of SyB C-1101 in Patients With Recurrent/Relapsed or Refractory Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 safety and pharmacokinetics study of SyB C-1101 in patients with myelodysplastic syndrome has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Safety and Pharmacokinetics Study of SyB L-1101 in Patients With Recurrent/Relapsed or Refractory Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 safety and pharmacokinetics study of SyB L-1101 in patients with recurrent/refractory or relapsed myelodysplastic syndrome has compl…