Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: PENELOPE Observational Study: Prophylaxis and Treatment of Arterial and Venous Thromboembolism
The PENELOPE observational study, which examined prophylaxis and treatment of arterial and venous thromboembolism in patients with hematolog…
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 1]
A Phase 1 study evaluating ipilimumab in patients with relapsed or refractory high-risk myelodysplastic syndrome or acute myeloid leukemia h…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: Non-Myeloablative HLA-Matched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies [Phase 2]
A Phase 2 study of non-Myeloablative HLA-matched ex-vivo T-cell depleted stem cell transplantation for hematologic malignancies was terminat…
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating atorvastatin for prophylaxis of acute graft-versus-host disease in patients undergoing HLA-mon donor hematopoietic …
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: A Study of Combined Deferasirox, Vitamin D and Azacytidine in High Risk MDS [Phase 1, Phase 2]
A combined therapy study (deferasirox, vitamin D, azacytidine) in high-risk myelodysplastic syndromes is in Phase 1/Phase 2 with unknown sta…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: Total Marrow Irradiation for Refractory Acute Leukemia [Phase 1]
A Phase 1 trial evaluating total marrow irradiation for refractory acute leukemia has completed enrollment/status; the study included patien…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients [Phase 2]
This Phase 2 open-label pharmacokinetic/pharmacodynamic trial evaluated CPX-351 (cytarabine:daunorubicin liposome injection) for potential Q…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients [Phase 2]
Phase 2 clinical trial of microtransplantation for refractory or relapsed hematologic malignancies in younger patients was terminated, with …
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CLINICAL_TRIALS trial_result · 2017-09-14Clinical Trial Update: Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS [Phase 1, Phase 2]
A safety study evaluating mocetinostat in combination with azacitidine in patients with myelodysplastic syndrome completed Phase 1 and Phase…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Donor Peripheral Blood Stem Cell Transplant and Pretargeted Radioimmunotherapy in Treating Patients With High-Risk Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome [Phase 1]
Phase 1 trial evaluating donor peripheral blood stem cell transplantation in combination with pretargeted radioimmunotherapy for patients wi…
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CLINICAL_TRIALS trial_result · 2017-08-24Clinical Trial Update: Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating chemotherapy followed by unrelated donor stem cell transplantation for blood and immune system cancers; …
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: PK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemias [Phase 1]
Phase 1 pharmacokinetic study of oral and intravenous clofarabine in high-risk myelodysplastic syndrome and acute leukemias; the trial has c…
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies Undergoing Single Umbilical Cord Blood Transplant [Phase 2]
Phase 2 clinical trial update assessing safety and tolerability of HSC835 in patients with hematological malignancies undergoing single umbi…
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CLINICAL_TRIALS trial_result · 2017-08-09Clinical Trial Update: Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies [Phase 2]
This Phase 2 randomized trial comparing haplo cord blood transplantation versus double umbilical cord blood transplantation for hematologic …
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Decitabine, Vorinostat, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
This Phase 1 trial evaluated the safety and preliminary activity of a three-drug combination—decitabine, vorinostat, and cytarabine—in patie…
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: Busulfan/Clofarabine + Allogeneic Stem Cell Transplantation [Phase 2]
This Phase 2 clinical trial update reports results for busulfan and clofarabine conditioning followed by allogeneic stem cell transplantatio…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Post Transplant Donor Lymphocyte Infusion [Phase 2]
Phase 2 clinical trial update for post-transplant donor lymphocyte infusion; the study is terminated with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Clofarabine and Cytarabine in Treating Older Patients With AML or High-Risk MDS [Phase 1, Phase 2]
Clinical trial update of a Phase 1/2 study evaluating the combination of clofarabine and cytarabine in older patients with acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Safety of Peptide Vaccination for Patients With Myelodysplastic Syndrome [Phase 1]
This clinical trial update reports safety findings from a Phase 1 study of a peptide vaccine in patients with myelodysplastic syndrome, with…
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Unrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells [Phase 1]
A Phase 1 trial of unrelated umbilical cord blood transplantation augmented with ALDHbr cord blood cells has completed, with the update desc…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Efficacy and Safety of ON 01910.Na in Myelodysplastic Syndrome (MDS) Patients With Trisomy 8 or Classified as Intermediate-1, -2 or High Risk [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of ON 01910.Na in patients with myelodysplastic syndrome, including those with tri…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating the efficacy and safety of oral rigosertib in transfusion-dependent myelodysplastic syndrome, including lower- and …
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Safety and Pharmacokinetic Study of Oral ON 01910.Na in Patients With Myelodysplastic Syndrome [Phase 1]
Phase 1 safety and pharmacokinetic study of ON-01910.Na (rigosertib) in patients with myelodysplastic syndrome has been completed, reporting…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Decitabine and Vorinostat Conditioning Followed by CD3-/CD19- NK Cells Infusion for High Risk Myelodysplastic Syndromes [Phase 2]
Phase 2 trial evaluating decitabine and vorinostat conditioning followed by CD3-/CD19- NK cell infusion in high-risk myelodysplastic syndrom…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and tolerability of HSC835 in patients with various hematologic malignancies completed with results posted …