Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Nonmyeloablative Preparative Regimen Using Mylotarg for Patients With High Risk Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myeloid Leukemia (CML) and Myelodysplastic Syndrome (MDS) [Phase 2, Phase 3]
A nonmyeloablative preparative regimen using Mylotarg (gemtuzumab ozogamicin) was studied in Phase 2/Phase 3 trials for high-risk acute myel…
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Combination Study of Deferasirox and Erythropoietin in Patients With Low- and Int-1-risk Myelodysplastic Syndrome. [Phase 2]
Phase 2 trial evaluating the combination of deferasirox and erythropoietin in patients with low- and int-1-risk myelodysplastic syndrome has…
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CLINICAL_TRIALS trial_result · 2018-10-18Clinical Trial Update: Study of Sensitization of Non-M3 AML Blasts to ATRA by Epigenetic Treatment With Tranylcypromine (TCP) [Phase 1, Phase 2]
A clinical trial investigating sensitization of non-M3 acute myeloid leukemia blasts to all-trans retinoic acid using epigenetic treatment w…
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS [Phase 2]
Phase 2 study evaluating multiple-dose, dose-escalation of AEB1102 in patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome has …
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: Trial of High Dose Lenalidomide in Patients With MDS and AML With Trilineage Dysplasia [Phase 2]
Phase 2 trial of high-dose lenalidomide in myelodysplastic syndrome (MDS) with trilineage dysplasia; study terminated with results posted in…
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Darbepoetin Alfa MDS Companion Protocol [Phase 3]
Phase 3 clinical trial update for darbepoetin alfa MDS companion protocol completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-10-03Clinical Trial Update: Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission [Phase 2]
Phase 2 trial of MLN9708 as maintenance therapy in AML and high-risk MDS patients in remission was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers [Phase 2]
Phase 2 trial evaluating cyclosporine with T-cell add-back in blood cell transplant settings for hematologic cancers, including chronic lymp…
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: Phase 2 Study of Pracinostat With Azacitidine in Patients With Previously Untreated Myelodysplastic Syndrome [Phase 2]
Phase 2 study of pracinostat with azacitidine in previously untreated myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Adoptive Transfer of Haplo-identical DLI for AML and MDS [Phase 1, Phase 2]
Clinical trial update for adoptive transfer of haplo-identical donor lymphocyte infusion in AML and MDS, completed with posted results in 20…
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine [Phase 2]
Phase 2 trial evaluating hematopoietic stem cell transplantation after a chemotherapy-only cytoreduction with busulfan, cyclophosphamide, an…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: A Phase II Pilot Study to Assess the Presence of Molecular Factors Predictive for Hematologic Response in Myelodysplastic Syndrome Patients Receiving Deferasirox Therapy. [Phase 2]
Phase II pilot study evaluating molecular factors predicting hematologic response in myelodysplastic syndrome patients treated with deferasi…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Improving Blood Stem Cell Collection and Transplant Procedures [Phase 1, Phase 2]
Phase 1/2 clinical trial update focused on improving blood stem cell collection and transplant procedures, completed with results reported b…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic Cancers [Phase 2]
Phase 2 trial evaluating reduced-intensity, related-donor bone marrow transplantation followed by high-dose cyclophosphamide for hematologic…
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: Cladribine Dose Escalation in Conditioning Regimen Prior to Allo-HSCT for Refractory Acute Leukemia and Myelodysplastic Syndromes [Phase 1]
A Phase 1 trial update exploring dose escalation of cladribine in conditioning regimens before allogeneic stem cell transplantation for refr…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Study of Clinical Efficacy and Safety of Tosedostat in MDS [Phase 2]
Phase 2 study evaluating the efficacy and safety of tosedostat in myelodysplastic syndrome has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands [Phase 1]
Phase 1 safety study of CYAD-01, CAR T cells targeting NKG2D-ligands, completed; evaluated in acute myeloid leukemia, myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901) [Phase 3]
Phase 3 trial comparing reduced intensity conditioning to myeloablative conditioning for acute myeloid leukemia and myelodysplastic syndrome…
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CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid Leukemia [NA]
ClinicalTrials.gov update on a completed trial evaluating CPX-351 (liposomal cytarabine-daunorubicin) for untreated myelodysplastic syndrome…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: Treo/Flu/TBI With Donor Stem Cell Transplant for Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating Treo/Flu/TBI with donor stem cell transplant for myelodysplastic syndrome or acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Tacrolimus, Bortezomib, & Thymoglobulin in Preventing Low Toxicity GVHD in Donor Blood Stem Cell Transplant Patients [Phase 2]
Phase 2 trial evaluating a three-drug regimen (Tacrolimus, Bortezomib, and Thymoglobulin) to prevent low-toxicity graft-versus-host disease …
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CLINICAL_TRIALS trial_result · 2018-04-25Clinical Trial Update: Clofarabine and Non-Myeloablative Allogeneic Hematopoietic Transplantation [Phase 1, Phase 2]
A phase 1/2 trial of Clofarabine combined with non-myeloablative allogeneic hematopoietic transplantation was terminated, with results poste…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Bortezomib for Low or Intermediate-1 Myelodysplastic Syndrome (MDS) With p65 Activation [Phase 2]
A Phase 2 clinical trial of bortezomib in patients with low or intermediate-1 myelodysplastic syndrome with p65 activation has completed, wi…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor [NA]
Clinical trial update on biparental HLA haplotype disparate T-cell depleted transplants for patients without an HLA-compatible donor has bee…
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm [NA]
This clinical trial update reports results for using decitabine plus cytarabine in older adults with untreated acute myeloid leukemia, high-…