Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Selinexor Combined With Venetoclax Maintenance Therapy After Allo-HSCT [Phase 2]
Phase 2 clinical trial update evaluating the combination of selinexor and venetoclax as maintenance therapy after allogeneic hematopoietic s…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: A Phase 1 Study of FD-001 in Recurrent /Refractory (R/R)AML/NHL/MM/MDS [Phase 1]
A Phase 1 study of FD-001 in recurrent/refractory acute myeloid leukemia, non-Hodgkin lymphoma, multiple myeloma, and myelodysplastic syndro…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS [Phase 2]
A Phase 2 clinical trial update investigating repurposing metformin as a leukemia-preventive drug for clonal hematopoiesis with CCUS and low…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies [Phase 1]
Phase 1 study of VIP943 in adults with advanced CD123+ hematologic malignancies is currently recruiting, including acute myeloid leukemia, B…
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or β-thalassemia
A post-marketing surveillance study to assess the safety of luspatercept in Korean patients with myelodysplastic syndrome or beta-thalassemi…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Revisiting the Universal Donor: Does Exposure to O Blood Products Affect Patient Outcomes? [NA]
Clinical trial in recruitment assessing whether exposure to O-type blood products affects patient outcomes in myelodysplastic syndrome. Spon…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Tolerability and Efficacy of Midostaurin to 10-day Decitabine in Unfit Adult AML and High Risk MDS Patients [Phase 2]
Phase 2 clinical trial evaluating tolerability and efficacy of adding midostaurin to a 10-day decitabine regimen in unfit adults with acute …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Clinical Registration Study of Haplo-HSCT for Elderly Patients With Acute Leukemia/ Myelodysplastic Syndrome
Registration study evaluating haploidentical hematopoietic stem cell transplantation for elderly patients with acute leukemia or myelodyspla…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Cytogenetic Studies in Acute Leukemia and Multiple Myeloma
Update on cytogenetic studies in acute leukemia and multiple myeloma; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Study of NEROFE, a Novel Hormone-Peptide in Adult Patients With Advanced MDS and AML [Phase 1]
Phase 1 clinical trial update for NEROFE, a novel hormone-peptide, in adults with advanced myelodysplastic syndrome and acute myeloid leukem…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant [Phase 1, Phase 2]
This clinical trial update examines using CD34+ malignant stem cell selection for patients receiving allogeneic stem cell transplants in Pha…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Pilot Study of CC 486 (Oral Azacitidine) Plus BSC as Maintenance After sc Azacitidine in Elderly HR-IPSS-R MDS Patients [Phase 2]
Pilot Phase 2 study evaluating CC-486 (oral azacitidine) plus best supportive care as maintenance after subcutaneous azacitidine in elderly …
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CLINICAL_TRIALS research · 2019-09-06Clinical Trial Update: Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Clinical trial assessing electrophysiological biomarkers of chemotherapy-related cognitive impairment and recovery; study completed with pos…
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CLINICAL_TRIALS research · 2018-03-20Clinical Trial Update: Phase I/II Study With Oral Panobinostat Maintenance Therapy Following Allogeneic Stem Cell Transplantation in Patients With High Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This is a Phase I/II clinical trial evaluating oral panobinostat as maintenance therapy after allogeneic stem cell transplantation in patien…
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CLINICAL_TRIALS research · 2017-12-08Clinical Trial Update: Effect of Chemotherapy vs No Chemotherapy Pre-transplant to MDS Undergoing Allo-HSCT
This trial compares pre-transplant chemotherapy versus no chemotherapy in patients with myelodysplastic syndrome undergoing allogeneic stem …
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: DLAAG in the Treatment of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome With Blast Excess [Phase 2]
A Phase 2 clinical trial evaluating DLAAG for acute myeloid leukemia and myelodysplastic syndrome with blast excess, with status currently u…
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CLINICAL_TRIALS research · 2017-01-12Clinical Trial Update: ED-TBI Followed By Allogeneic Stem Cell Transplantation For The Treatment Of Refractory AML And Advanced MDS [Phase 2]
Phase 2 trial evaluating external total body irradiation followed by allogeneic stem cell transplantation for refractory acute leukemia and …
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CLINICAL_TRIALS research · 2016-12-21Clinical Trial Update: Myelodysplasic Syndromes and Risk Factors for Infection
A clinical trial update exploring risk factors for infection in patients with myelodysplastic syndrome, including high-risk IPSS status.
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CLINICAL_TRIALS research · 2016-11-16Clinical Trial Update: MDS-CAN: A Prospective National MDS Clinical Database and Local Tissue Bank
A prospective national myelodysplastic syndrome clinical database and local tissue bank (MDS-CAN) is being established, sponsored by Sunnybr…
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CLINICAL_TRIALS research · 2016-05-11Clinical Trial Update: Lenalidomide After Failure of Hypomethylating Agents in Myelodysplastic Syndrome [Phase 2]
Clinical trial update on lenalidomide for myelodysplastic syndrome after failure of hypomethylating agents; Phase 2 study status.
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CLINICAL_TRIALS research · 2015-04-24Clinical Trial Update: A Study of the Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q [Phase 2]
This is a Phase 2 clinical trial evaluating lenalidomide combined with escalating-dose chemotherapy for intermediate-2 or high-risk myelodys…
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CLINICAL_TRIALS research · 2014-06-24Clinical Trial Update: Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS) [Phase 2]
An update on the Phase 2 study of AR-67 (DB-67) for Myelodysplastic Syndrome. The current trial status is UNKNOWN.
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CLINICAL_TRIALS research · 2014-03-26Clinical Trial Update: Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single Vaccination [Phase 1, Phase 2]
Open-label Phase 1/2 clinical trial evaluating the safety and tolerability of donor-derived allogeneic B-cell concentrates to support immune…
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CLINICAL_TRIALS research · 2014-02-12Clinical Trial Update: Prognostic Molecular Markers in Patients With Myelodysplastic Syndrome
This completed clinical trial investigated prognostic molecular markers in patients with myelodysplastic syndrome.
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CLINICAL_TRIALS research · 2014-01-22Clinical Trial Update: The Effect of Combination Ultra Q10 and L-carnitine on the Course of Myelodysplastic Syndrome [Phase 2, Phase 3]
This clinical trial update discusses a study evaluating Ultra Q10 plus L-carnitine in myelodysplastic syndrome (Phase 2/Phase 3) with the st…