Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: FHD-286 With Low-Dose Weekly Decitabine/Venetoclax in Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 study evaluating FHD-286 in combination with low-dose weekly decitabine and venetoclax in adults with acute myeloid leukemia or myel…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies [Phase 2]
Phase 2 clinical trial update describing a donor stem cell transplant conditioning regimen with treosulfan, fludarabine, and total-body irra…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies [Phase 1, Phase 2]
A first-in-human study evaluating HLA partially to fully matched allogeneic, cryopreserved deceased donor bone marrow transplantation for va…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Azacitidine and Chimerism in MDS or AML Patients After Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating azacitidine and chimerism in patients with myelodysplastic syndrome or acute myeloid leukemia after alloge…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome) [Phase 1]
Phase 1 study evaluating rezatapopt in combination with azacitidine for TP53Y220C mutant myeloid malignancies (acute myeloid leukemia or mye…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Venetoclax in Combination With ASTX727 for the Treatment of Treatment-Naive High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluates venetoclax combined with ASTX727 (oral decitabine/cedazuridine) in treatment-naive high-risk myelodyspl…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Nivolumab and Ipilimumab After Donor Stem Cell Transplant in Treating Patients With High Risk Refractory or Relapsed Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 trial update evaluating the combination of nivolumab and ipilimumab after donor stem cell transplantation in patients with high-ri…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial update evaluating busulfan, fludarabine phosphate, and post-transplant cyclophosphamide in patients with hematologi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders [Phase 2]
Phase 2 clinical trial update evaluating a geriatric assessment to guide treatment planning for older adults with myelodysplastic syndromes,…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Cladribine Plus Low Dose Cytarabine (LDAC) Alternating With Decitabine in Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial evaluating alternating regimens of cladribine plus low-dose cytarabine with decitabine for acute myeloid leukemia or high-risk…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer [Phase 2]
Phase 2 clinical trial evaluating FLAG-Ida chemotherapy followed by reduced-intensity total body irradiation and donor hematopoietic cell tr…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia [Phase 2]
Phase 2 clinical trial evaluating Total Marrow and Lymphoid Irradiation as a conditioning regimen before hematopoietic cell transplantation …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 2]
This Phase 2 clinical trial compares treosulfan-based versus clofarabine-based conditioning regimens before donor allogeneic stem cell trans…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies [Phase 1]
Phase 1 clinical trial evaluating a CD70-directed CAR T-cell therapy for pediatric hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases [Phase 2]
Phase 2 clinical trial evaluating a cord blood transplant using cyclophosphamide, fludarabine, and total-body irradiation in high-risk hemat…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 1]
Clinical trial update indicates CLN-049 is being studied for relapsed/refractory acute myeloid leukemia and myelodysplastic syndrome in a Ph…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: A Phase 1 Study of CG009301 for Injection in Adult Subjects With Recurrent or Refractory Haematological Malignancies [Phase 1]
A Phase 1 study evaluating CG009301 for injection in adults with recurrent or refractory hematologic malignancies; recruitment is ongoing fo…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: CART123 T Cells in Relapsed or Refractory CD123+ Hematologic Malignancies: A Dose Escalation Phase I Trial [EARLY_Phase 1]
This update describes an early-phase dose-escalation trial evaluating CART123 T cells in relapsed or refractory CD123+ hematologic malignanc…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/2 clinical trial at MD Anderson evaluating a triple combination of Quizartinib, Decitabine, and Venetoclax for untreated or relaps…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells [Phase 2]
This Phase 2 clinical trial evaluates allogeneic hematopoietic stem cell transplantation using G-CSF mobilized CD34+ selected cells co-infus…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating palifermin in combination with leuprolide acetate to promote immune recovery after total body irradiation-…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Safety and Feasibility of Sulforaphane to Promote Early Haematopoietic Recovery After Cord Blood Transplantation [NA]
A clinical trial is evaluating the safety and feasibility of sulforaphane to promote early hematopoietic recovery after cord blood transplan…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome [Phase 3]
A Phase 3 clinical trial comparing mismatched related donor versus matched unrelated donor stem cell transplantation in children, adolescent…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: 211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia [Phase 1, Phase 2]
Clinical trial update for 211At-BC8-B10 given before donor stem cell transplant in high-risk acute myeloid leukemia, acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies [Phase 1, Phase 2]
A Phase 1/2 study is evaluating CCS1477 (Inobrodib) in multiple hematologic malignancies and is currently recruiting.