Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial evaluating BMS-986497 (ORM-6151) as monotherapy and in dual/triple combinations with azacitidine and venetoclax in re…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study [Phase 1, Phase 2]
PedAL BCU, LLC is conducting a pediatric screening trial to test bone marrow and blood methods in children with relapsed or hard-to-treat ac…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: WearAble Technology for Collecting Health Data in People Who Are the Transfused (WATCH Transfused) - A UK Exploratory Study to Improve Quality of Life and the Efficacy of Transfusion Supportive Care in People With Blood Cancers Undergoing Treatment
An exploratory UK clinical trial sponsored by the University of Oxford is evaluating wearable technology to collect health data in people wi…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Seclidemstat and Azacitidine for the Treatment of Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia [Phase 1, Phase 2]
Clinical trial update indicates Seclidemstat in combination with azacitidine is being studied for myelodysplastic syndrome or chronic myelom…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating a multi-agent regimen of fludarabine phosphate, cytarabine, filgrastim-sndz, gemtuzumab ozogamicin, and idarubicin …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating CMV-MVA Triplex Vaccine to enhance CMV-specific immunity and prevent CMV viremia in patients undergoing ha…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF) [Phase 1]
CERo Therapeutics is conducting a Phase 1 trial of CER-1236 for acute myeloid leukemia, myelodysplastic syndrome, and myelofibrosis; the stu…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms
This clinical trial update discusses a study of acquired pyruvate kinase deficiency in clonal myeloid neoplasms. The trial is currently acti…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS [Phase 1]
Phase 1 clinical trial update evaluating the combination of everolimus (RAD001) with midostaurin (PKC412) in relapsed, refractory, or poor-p…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Luspatercept + Darbepoetin in MDS [Phase 2]
Phase 2 clinical trial evaluating the combination of luspatercept and darbepoetin in myelodysplastic syndrome is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Assessment of Chimerism and Relapse Post Bone Marrow/Hematopoietic Cell Transplant (HCT) Using AlloHeme Test
A clinical trial update evaluating the AlloHeme test for assessing chimerism and detecting relapse after bone marrow/hematopoietic cell tran…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation [Phase 2]
This Phase 2 clinical trial protocol investigates a post-transplant cyclophosphamide–based graft-versus-host disease prophylaxis approach in…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms [Phase 2]
A Phase 2 clinical trial evaluating decitabine in combination with JAK inhibitors (ruxolitinib, fedratinib, or pacritinib) for accelerated o…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias [Phase 1]
Clinical trial update for CBX-250 in relapsed or refractory myeloid leukemias (Phase 1) that is currently recruiting at Crossbow Therapeutic…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders [Phase 2]
Phase 2 clinical trial evaluating cord blood transplant in children and young adults with blood cancers and select non-malignant disorders; …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS) [Phase 2]
This is a Phase 2 clinical trial update evaluating strategies to reduce graft-versus-host disease in donor blood stem cell transplant patien…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating combinations of ivosidenib and venetoclax with or without azacitidine in IDH1-mutated hematologic mali…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating CMV-MVA Triplex vaccination in HLA-matched related stem cell donors to prevent cytomegalovirus infection i…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
A Phase 1b/2a clinical trial evaluating Nadunolimab in combination with azacitidine, with or without venetoclax, for myelodysplastic syndrom…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy
Clinical trial update from University Health Network, Toronto evaluating the risk of myelodysplastic syndrome and acute myeloid leukemia in …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant [Phase 1]
Phase 1 clinical trial update evaluating maintenance therapy with tagraxofusp and azacitidine in CD123-positive acute myeloid leukemia and m…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation [Phase 2]
Phase 2 trial update on enasidenib with azacitidine for recurrent or refractory acute myeloid leukemia with IDH2 mutation, currently recruit…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant [Phase 1]
A Phase 1 clinical trial update assessing olutasidenib for IDH1-mutated acute myeloid leukemia, myelodysplastic syndrome, or chronic myelomo…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
This ongoing Phase 1/2 clinical trial is evaluating venetoclax in combination chemotherapy for newly diagnosed or relapsed/refractory acute …
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS [Phase 1]
Phase 1 study of AUTX-703 for relapsed or refractory acute myeloid leukemia and relapsed/refractory myelodysplastic syndromes is active but …