Multiple Sclerosis
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Testing the Effects of Methylphenidate on Multiple Sclerosis [Phase 2]
A Phase 2 clinical trial evaluating the effect of methylphenidate on fatigue in individuals with multiple sclerosis has completed. The docum…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: A Study of Imaging in Demyelinating Diseases [Phase 2]
Phase 2 clinical trial update focused on imaging in demyelinating diseases, including multiple sclerosis and inflammatory demyelinating dise…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Evaluation of the Relationship Between Optic Nerve Diameter and Optic Nerve Sheath Diameter Measured by Transorbital Sonography With Clinical, Radiological, and Electrophysiological Parameters in Multiple Sclerosis Patients
Completed clinical trial evaluating the relationship between optic nerve diameter and optic nerve sheath diameter in multiple sclerosis pati…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Testosterone Treatment for Erectile Dysfunction and Multiple Sclerosis [Phase 4]
Phase 4 clinical trial update on testosterone treatment for erectile dysfunction in men with multiple sclerosis; the study is currently not …
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Acute Effects of Walking Exercise on Brain Functioning in Multiple Sclerosis [EARLY_Phase 1]
An early-phase trial studying the acute effects of walking exercise on brain functioning in people with Multiple Sclerosis; the study is cur…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: WEBCAMS: Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis [Phase 1]
Phase 1 clinical trial evaluating WEBCAMS, a walking exercise program, for brain and cognitive outcomes in adults with multiple sclerosis.
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Allogeneic Mesenchymal Stem Cell-Derived Exosome Therapy for Progressive Multiple Sclerosis [EARLY_Phase 1]
A Phase 1 trial of allogeneic mesenchymal stem cell-derived exosome therapy for progressive multiple sclerosis has been suspended. Sponsor B…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Study Evaluating Kesimpta® Treatment Effects in Patients With Relapsing Multiple Sclerosis Transitioning From Other Therapies
This document reports the completion of a clinical trial evaluating Kesimpta (ofatumumab) in relapsing multiple sclerosis patients transitio…
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EMA approval · 2025-08-26EMA Authorised: Dimethyl fumarate Accord (dimethyl fumarate) — Accord Healthcare Ltd
The EMA authorised a Dimethyl fumarate product from Accord Healthcare Ltd for the treatment of multiple sclerosis.
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Noninvasive Vagal Nerve Stimulation [NA]
Clinical trial update on noninvasive vagal nerve stimulation for multiple sclerosis; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: A Health Action Process Approach Online Intervention for People With Multiple Sclerosis [NA]
Clinical trial update describing an online Health Action Process Approach intervention for people with Multiple Sclerosis, sponsored by the …
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Predictive Value of the Optic Nerve Involvement in Clinically Isolated Syndrome [NA]
An ongoing clinical study investigates whether optic nerve involvement can predict progression in Clinically Isolated Syndrome and multiple …
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Quality Improvement and Practice Based Research in Neurology Using the EMR [Phase 4]
Phase 4 clinical trial focusing on quality improvement and practice-based research in neurology using electronic medical records. It is curr…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: An Individualized-health eLibrary App for People With Multiple Sclerosis [NA]
This entry reports on a clinical trial evaluating an individualized-health eLibrary app for people with Multiple Sclerosis. The study is cur…
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FDA approval · 2025-08-22FDA Approved: GILENYA — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for GILENYA (fingolimod HCl) from Novartis Pharmaceuticals Corporation. The decision constitutes…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders [Phase 2]
This Phase 2 trial evaluating a COVID-19 booster vaccine in autoimmune-disease non-responders was terminated, with results posted on 2025-08…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Prospective Randomized Endovascular Therapy in Multiple Sclerosis [NA]
The University at Buffalo-sponsored prospective randomized trial evaluating endovascular therapy for multiple sclerosis has completed, with …
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension [NA]
A clinical trial evaluating vascular mechanisms, functional outcomes, and exercise interventions in people with both multiple sclerosis and …
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners [NA]
A clinical trial evaluating high-intensity functional training for individuals with neurologic conditions and their care partners has comple…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: The Effect of Obesity on Contralateral Suppression in Patients With Multiple Sclerosis [NA]
A completed clinical study examining the effect of obesity on contralateral suppression in patients with multiple sclerosis.
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EMA approval · 2025-08-21EMA Authorised: Fampyra (Fampridine) — Merz Therapeutics GmbH
The EMA authorised Fampyra (fampridine) by Merz Therapeutics GmbH for multiple sclerosis, confirming its use to improve walking in patients …
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FDA approval · 2025-08-21FDA Approved: MAYZENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for MAYZENT (siponimod) to expand its indication to include treatment of secondary progressive multi…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Serum 25-Hydroxyvitamin D and Neurological Disability in Multiple Sclerosis
A completed clinical trial evaluating the relationship between serum 25-hydroxyvitamin D levels and neurological disability in individuals w…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Effect of Resistance Training on Psychophysiological Indicators in People With Multiple Sclerosis [NA]
Clinical trial update indicating the completion of a study evaluating the effects of resistance training on psychophysiological indicators i…
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FDA approval · 2025-08-18FDA Approved: KESIMPTA — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for Kesimpta (ofatumumab) from Novartis Pharmaceuticals Corporation.