Multiple Sclerosis
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation [Phase 4]
Phase 4 trial evaluating whether ocrelizumab reduces neuroinflammation in multiple sclerosis as measured by 11C-PBR28 MR-PET imaging of micr…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: The Validity and Reliability of the Modified O'Sullivan Functional Balance (mOFB) Test for Multiple Sclerosis
This clinical trial update reports on the validity and reliability of the Modified O'Sullivan Functional Balance (mOFB) test for assessing b…
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent [Phase 2]
Phase 2 ascending-dose study of RVP-001, a manganese-based MRI contrast agent, completed to assess safety and preliminary efficacy in CNS le…
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Probiotic Intervention for People With Multiple Sclerosis [NA]
A clinical trial evaluating a probiotic intervention for people with multiple sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Emotions in Multiple Sclerosis [NA]
A completed clinical trial examining emotions in people with multiple sclerosis, sponsored by Lille Catholic University.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Survey Among Healthcare Professionals and MS Patients to Assess Their Understanding of RMP Materials
A completed clinical trial assessing how well healthcare professionals and multiple sclerosis patients understand risk management plan (RMP)…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Study Evaluating SARS-CoV-2 (COVID-19) Humoral Response After BNT162b2 Vaccine in Immunocompromised Adults Compared to Healthy Adults [Phase 4]
This Phase 4 trial assessed the humoral immune response to the Pfizer-BioNTech COVID-19 vaccine (BNT162b2) in immunocompromised adults compa…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Implication of 5-HT7 Receptor in Inflammatory Mechanisms in Multiple Sclerosis
This clinical trial update investigates whether the 5-HT7 receptor plays a role in inflammatory mechanisms in multiple sclerosis; the study …
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Effect of Visually-Guided Gait Training on Balance, Mobility and Risk of Falling in Patients With Multiple Sclerosis [NA]
This clinical trial update describes the status of a study examining whether visually-guided gait training improves balance, mobility, and r…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Effects of Motor Imagery and Action Observation in People With Multiple Sclerosis [NA]
A completed clinical trial investigated the effects of motor imagery and action observation in people with multiple sclerosis.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis. [Phase 2]
A Phase 2 trial using 31P-MRS imaging to evaluate CNM-Au8's effects on impaired neuronal redox state in people with Multiple Sclerosis has c…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Prospective Longitudinal Monocentric Study to Evaluate the Syde® Digital Endpoint in Patients With Multiple Sclerosis
A prospective longitudinal study evaluating the Syde digital endpoint in patients with Multiple Sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy [Phase 2]
Phase IIa randomized, double-blind, placebo-controlled trial completed to evaluate whether the combination of metformin and clemastine can p…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Description Des Troubles Respiratoires Chez Les Patients Suivis Pour Une Sclérose en Plaques (SEP) sévère [NA]
A completed clinical trial update (NCT03339817) from INSERM France describing respiratory disorders observed in patients with severe multipl…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Effect of Hydrotherapy on Multiple Sclerosis [NA]
This clinical trial update notes the completion of a study evaluating hydrotherapy for multiple sclerosis. No results are provided in the sn…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Psychological Interventions for Multiple Sclerosis: Effects on Anxiety, Depression, and Cognition. [NA]
Completed clinical trial evaluating psychological interventions, including cognitive-behavioral therapy, for people with relapsing-remitting…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Effects of Lower Extremity Neuromuscular Facilitation and Patients With Multiple Sclerosis [NA]
A completed clinical trial evaluating lower extremity neuromuscular facilitation in people with multiple sclerosis, focusing on gait, balanc…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Effect of TTNS and PNS on Neurogenic Overactive Bladder Symptoms in Female Patients With Multiple Sclerosis. [NA]
A completed clinical trial evaluating transcutaneous tibial nerve stimulation (TTNS) and peripheral nerve stimulation (PNS) for neurogenic o…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Libyan Multiple Sclerosis Registry Study
The Libyan Multiple Sclerosis Registry study (NCT07264725) conducted by the University of Zintan is marked as completed.
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Clinical Monitoring, MRI and Neuro-Ophthalmology of a Cohort of Patients With a Clinically Isolated Syndrome (CIS)
This completed clinical trial update describes monitoring, MRI and neuro-ophthalmology assessments in a cohort of patients with Clinically I…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Upper Limb Muscle Strength Models for Patients With Motor Impairment. [NA]
A completed clinical trial investigating upper limb muscle strength models for patients with motor impairment due to stroke, multiple sclero…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Rehabilitation Protocol for Disorders on Hand Sensitivity in Multiple Sclerosis Patients. [NA]
A clinical trial evaluating a rehabilitation protocol for hand sensitivity issues in multiple sclerosis patients has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Deficit-specific Training in Spinal Disorders [NA]
The University of Zurich study on deficit-specific rehabilitation training for spinal cord injuries and multiple sclerosis has completed; no…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Prognostic Value of Three New Biomarkers of Multiple Sclerosis in Patients With Radiologically Isolated Syndrome
This clinical trial update evaluates whether three novel biomarkers have prognostic value for progression from radiologically isolated syndr…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Personalized Nutrition Advice for Optimizing Dietary Calcium Intake in MS Patients [NA]
This ClinicalTrials.gov entry reports a completed study investigating personalized nutrition advice to optimize dietary calcium intake in pe…