Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Gemcitabine Plus Busulfan, Melphalan and Hematopoietic Cell Transplant for Advanced Lymphoid Malignancies [Phase 1]
Phase 1 trial evaluating a conditioning regimen of gemcitabine, busulfan, and melphalan with hematopoietic cell transplantation for advanced…
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Bortezomib Based Consolidation in Multiple Myeloma Patients Completing Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating bortezomib-based consolidation in multiple myeloma patients after stem cell transplantation has completed …
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CLINICAL_TRIALS research · 2016-06-03Clinical Trial Update: Adherence to Lenalidomide Treatment in Multiple Myeloma - Prevalence, Characteristics and Clinical Significance
This clinical trial update examines adherence to lenalidomide therapy in multiple myeloma, including prevalence, characteristics of non-adhe…
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CLINICAL_TRIALS research · 2016-06-02Clinical Trial Update: Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma [Phase 1, Phase 2]
This document describes an open-label Phase 1/2 trial evaluating TH-302 (evofosfamide) with dexamethasone, with or without bortezomib or pom…
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CLINICAL_TRIALS trial_result · 2016-05-25Clinical Trial Update: Aurora A Kinase Inhibitor MLN8237 and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating alisertib (MLN8237) in combination with bortezomib for relapsed or refractory multiple myeloma has com…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Bendamustine, Bortezomib (Velcade ®) and Prednisone (BVP) in Patients Newly Diagnosed Multiple Myeloma [Phase 2]
Phase 2 clinical trial update evaluating bendamustine, bortezomib (Velcade), and prednisone (BVP) in newly diagnosed multiple myeloma. The s…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Total Skeletal Irradiation in Multiple Myeloma Before Second Autologous Hematopoietic Stem Cell Transplantation [Phase 1]
Phase 1 trial evaluating total skeletal irradiation before a second autologous hematopoietic stem cell transplantation in multiple myeloma. …
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FDA approval · 2016-05-12FDA Approved: MOZOBIL — Supplemental Application (Sanofi-Aventis U.S. LLC)
The FDA approved a supplemental application for Mozobil (plerixafor) from Sanofi-Aventis U.S. LLC.
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple Myeloma [Phase 2]
Open-label Phase 2 trial of imetelstat in patients with previously treated multiple myeloma has completed.
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Phase I Study of Sequential Cord Blood Transplants [Phase 1]
Phase I study of sequential cord blood transplants has completed enrollment for conditions including lymphoma, leukemia, multiple myeloma, a…
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CLINICAL_TRIALS trial_result · 2016-05-10Clinical Trial Update: Melphalan, Prednisone, Thalidomide and Defibrotide in Relapsed Multiple Myeloma Patients [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating a four-drug combination of melphalan, prednisone, thalidomide, and defibrotide in relapsed m…
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CLINICAL_TRIALS research · 2016-05-10Clinical Trial Update: Single Autologous Stem Cell Transplantation Followed by Maintenance Therapy as Front-line Treatment for Myeloma [Phase 3]
Phase 3 trial evaluating single autologous stem cell transplantation followed by maintenance therapy as front-line treatment for multiple my…
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CLINICAL_TRIALS trial_result · 2016-05-10Clinical Trial Update: RMPT for Relapsed/Refractory Multiple Myeloma [Phase 2]
A Phase 2 clinical trial evaluating RMPT for relapsed/refractory multiple myeloma has completed.
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CLINICAL_TRIALS withdrawal · 2016-05-10Clinical Trial Update: Vorinostat Plus Lenalidomide and Dexamethasone or Lenalidomide Plus Dexamethasone in Multiple Myeloma Patients Who Experience Biochemical Relapse During Lenalidomide Maintenance Therapy [Phase 2]
Phase 2 trial evaluating vorinostat plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone in multiple myeloma patients w…
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Phase 1 Study of TG02 Citrate in Patients With Advanced Hematological Malignancies [Phase 1]
Phase 1 study evaluating TG02 Citrate in patients with advanced hematologic malignancies has completed, including AML, ALL, blast crisis, MD…
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant
A Duke University registry study evaluating T-cell depleted allogeneic non-myeloablative stem cell transplantation for hematologic cancers h…
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CLINICAL_TRIALS trial_result · 2016-05-04Clinical Trial Update: Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Multiple Myeloma and Renal Disease [Phase 1]
This Phase 1 study evaluated the pharmacokinetics and safety of carfilzomib in patients with relapsed multiple myeloma and end-stage renal d…
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CLINICAL_TRIALS research · 2016-05-04Clinical Trial Update: A Study Conducted in Subjects With Relapsed/Refractory Multiple Myeloma (MM); to Determine Dose of Afuresertib in Combination With Carfilzomib (Part 1) and to Investigate the Safety, Pharmacokinetic and Clinical Activity of the Combination Compared With Carfilzomib Alone (Part 2) [Phase 1]
A Phase 1 study evaluating afuresertib in combination with carfilzomib for relapsed/refractory multiple myeloma, including dose determinatio…
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CLINICAL_TRIALS withdrawal · 2016-05-03Clinical Trial Update: Chemotherapy-Induced Peripheral Neuropathy Survey
A clinical trial evaluating chemotherapy-induced peripheral neuropathy has been withdrawn. The study involved patients with breast cancer, c…
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CLINICAL_TRIALS research · 2016-04-29Clinical Trial Update: Fractionated Stem Cell Infusions in Myeloma Patients Undergoing Autologous Stem Cell Transplant [NA]
Clinical trial investigating fractionated stem cell infusions in multiple myeloma patients undergoing autologous stem cell transplant; the s…
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FDA approval · 2016-04-28FDA Approved: CARMUSTINE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
The FDA approved a supplemental application for Carmustine submitted by Heritage Pharmaceuticals Inc. (doing business as Avet Pharmaceutical…
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FDA approval · 2016-04-22FDA Approved: POMALYST — Supplemental Application (Celgene Corporation)
The FDA approved a supplemental application for POMALYST (pomalidomide) submitted by Celgene Corporation. This action updates the drug's ind…
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CLINICAL_TRIALS research · 2016-04-20Clinical Trial Update: Thiotepa-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies [Phase 2]
Phase 2 clinical trial investigating thiotepa-based conditioning for allogeneic stem-cell transplantation in lymphoid malignancies, includin…
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CLINICAL_TRIALS research · 2016-04-20Clinical Trial Update: CyBorD vs. PAD in the Treatment of Newly Diagnosed Multiple Myeloma [Phase 3]
A Phase 3 clinical trial update comparing CyBorD with PAD for newly diagnosed multiple myeloma. The regimens consist of cyclophosphamide, bo…
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Phase I Study of an Oncofetal Antigen Multi-Peptide Immunotherapy in Subjects With Hematologic Cancer [Phase 1]
A Phase I clinical trial is evaluating an oncofetal antigen multi-peptide immunotherapy in hematologic cancers, including acute myeloid leuk…