Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Bone Marker Assessment of Multiple Myeloma Patients Treated With Aminobisphosphonates [Phase 2]
Phase 2 clinical trial update assessing bone marker responses in multiple myeloma patients treated with aminobisphosphonates; results have b…
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Multi-day Doses in Prevention of Nausea and Emesis [Phase 2]
Phase 2 trial evaluating multi-day dosing to prevent nausea and emesis in patients with multiple myeloma and lymphoma. The study completed a…
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Daratumumab (HuMax®-CD38) Safety Study in Multiple Myeloma [Phase 2]
Phase 2 safety study of daratumumab (HuMax-CD38) in multiple myeloma has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Phase 1-2 Amrubicin in Combo With Lenalidomide + Weekly Dexamethasone in Relapsed/Refractory Multiple Myeloma [Phase 1, Phase 2]
Phase 1-2 trial evaluating amrubicin in combination with lenalidomide and weekly dexamethasone in relapsed/refractory multiple myeloma has c…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Bendamustine + Pomalidomide + Dex in R/R Multiple Myeloma [Phase 1, Phase 2]
Phase 1/2 trial investigating bendamustine plus pomalidomide and dexamethasone in relapsed/refractory multiple myeloma.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: ATRA, Celecoxib, and Itraconazole as Maintenance [Phase 1]
A Phase 1 trial evaluated maintenance therapy with a triplet of ATRA (all-trans retinoic acid), celecoxib, and itraconazole in relapsed mult…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Melphalan, Lenalidomide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis [Phase 2]
This is a Phase 2 clinical trial update reporting results for melphalan, lenalidomide, and dexamethasone in AL amyloidosis (primary systemic…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Lenalidomide/Low-dose Dexamethasone in Combination With Continuous Oral Cyclophosphamide Compared to Lenalidomide/Low-dose Dexamethasone Combined With Single Cyclophosphamide Doses IV in Patients With Relapsed/Refractory Multiple Myeloma [Phase 1, Phase 2]
A completed Phase 1/2 trial comparing lenalidomide plus low-dose dexamethasone with continuous oral cyclophosphamide versus lenalidomide/dex…
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Study to Evaluate Optimized Retreatment and Prolonged Therapy With Bortezomib [Phase 3]
A Phase 3 trial evaluating optimized retreatment and prolonged therapy with bortezomib in multiple myeloma has completed.
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Lenalidomide After Donor Stem Cell Transplant and Bortezomib in Treating Patients With High Risk Multiple Myeloma [Phase 1]
Phase 1 trial evaluating lenalidomide after donor stem cell transplant with bortezomib in high-risk multiple myeloma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Safety/Efficacy Study of LDE225 (Sonidegib) Plus Bortezomib in Patients With Relapsed or Relapsed/Refractory Multiple Myeloma [Phase 2]
Phase 2 study evaluating LDE225 (sonidegib) in combination with bortezomib for relapsed or relapsed/refractory multiple myeloma was terminat…
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CLINICAL_TRIALS withdrawal · 2017-02-15Clinical Trial Update: A Open-label Study of Ultra-High Dose Dexamethasone for Relapsed Multiple Myeloma [Phase 2]
The open-label Phase 2 trial of ultra-high-dose dexamethasone for relapsed multiple myeloma has been withdrawn.
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CLINICAL_TRIALS research · 2017-02-14Clinical Trial Update: Pilot Study Exploring the Use of Hyperbaric Oxygen in Autologous Peripheral Blood Stem Cell Transplantation [NA]
Pilot study evaluating whether hyperbaric oxygen therapy can improve outcomes during autologous peripheral blood stem cell transplantation i…
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CLINICAL_TRIALS research · 2017-02-14Clinical Trial Update: Phase I Study of CS-7017 and Bexarotene [Phase 1]
Phase I trial of CS-7017 in combination with Bexarotene for solid tumors, lymphoma, and multiple myeloma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: A Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma [Phase 3]
This is a Phase 3 trial comparing daratumumab plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone in relapsed or refra…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Addition of Daratumumab to Combination of Bortezomib and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma [Phase 3]
A phase 3 trial assessed adding daratumumab to bortezomib and dexamethasone in relapsed or refractory multiple myeloma; results from the stu…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Allogeneic Cytokine-induced Killer Immunotherapy for Relapse After Allogeneic Marrow Transplant for Haematological Malignancies [Phase 1, Phase 2]
Phase 1 and Phase 2 results are reported for allogeneic cytokine-induced killer (CIK) cell immunotherapy given to patients who relapsed afte…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Epoetin Alfa or Darbepoetin Alfa in Treating Patients With Anemia Caused by Chemotherapy [Phase 2]
Phase 2 trial evaluating epoetin alfa or darbepoetin alfa for chemotherapy-induced anemia; results from a completed study were posted in 201…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Haploidentical Bone Marrow Stem Cell Transplantation in Patients With Multiple Myeloma [Phase 1, Phase 2]
This clinical trial update covers a phase 1/2 study evaluating haploidentical bone marrow stem cell transplantation in patients with multipl…
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: Velcade (Bortezomib) Consolidation After Transplant [Phase 3]
Phase 3 trial evaluating Velcade (bortezomib) as consolidation after transplant in multiple myeloma. The study is completed with results pos…
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CLINICAL_TRIALS research · 2017-02-09Clinical Trial Update: Comparing Intermediate-dose CTX+ G-CSF Plus or Not rhTPO for PB CD34+ Cells Mobilization in MM Patients [NA]
A clinical trial comparing intermediate-dose cyclophosphamide plus G-CSF with or without recombinant human thrombopoietin for mobilizing per…
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CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic Syndrome [NA]
This clinical trial update indicates the Lactobacillus probiotic study intended to prevent infection in patients undergoing donor stem cell …
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FDA approval · 2017-02-02FDA Approved: ZOLEDRONIC ACID — Supplemental Application (Sagent Pharmaceuticals)
FDA approved a supplemental application for zoledronic acid submitted by Sagent Pharmaceuticals, resulting in an approved labeling change. Z…
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD [Phase 2]
A Phase 2 clinical trial evaluating daratumumab in adults with multiple myeloma who had at least 3 prior therapies or were refractory to a P…
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: 2nd Autologous Stem Cell Transplant in Patients With Persistent/Recurrent (AL) Amyloidosis [Phase 2]
Phase 2 trial update evaluating a second autologous stem cell transplant in patients with persistent or recurrent AL amyloidosis, with resul…