Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2019-06-25Clinical Trial Update: A Clinical Research of BCMA-Targeted CAR-T in B Cell Malignancies [Phase 1, Phase 2]
A clinical trial update on a BCMA-targeted CAR-T therapy investigated in B cell malignancies across Phase 1 and Phase 2.
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CLINICAL_TRIALS research · 2019-06-20Clinical Trial Update: Study of Daratumumab in Multiple Myeloma (MM) Patients in >VGPR/MRD-positive [Phase 2]
A Phase 2 clinical trial update evaluating daratumumab in multiple myeloma patients who are >VGPR/MRD-positive.
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Study of Pomalidomide, Cyclophosphamide, Dexamethasone in Relapsed/Refractory Multiple Myeloma [Phase 2]
Phase 2 trial evaluating pomalidomide with cyclophosphamide and dexamethasone in relapsed/refractory multiple myeloma has completed.
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CLINICAL_TRIALS trial_result · 2019-06-10Clinical Trial Update: Pharmacokinetics Study of Oral Ixazomib (MLN9708) in Relapsed/Refractory Multiple Myeloma and Advanced Solid Tumors Participants With Normal Renal Function or Severe Renal Impairment [Phase 1]
Phase 1 pharmacokinetics study of oral ixazomib (MLN9708) in relapsed/refractory multiple myeloma and advanced solid tumors, including parti…
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CLINICAL_TRIALS trial_result · 2019-06-04Clinical Trial Update: B Cell Maturation Antigen（BMCA）-Targeted CAR-T for Refractory/Relapsed Multiple Myeloma [Phase 2]
Phase 2 clinical trial update for BMCA-targeted CAR-T therapy in refractory/relapsed multiple myeloma.
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CLINICAL_TRIALS trial_result · 2019-06-04Clinical Trial Update: Conditioning Regimen of Bendamustine and Melphalan Followed by Transplant in Patients With Multiple Myeloma [Phase 1, Phase 2]
Phase 1/2 study evaluating a conditioning regimen of bendamustine and melphalan followed by transplant in patients with multiple myeloma; st…
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CLINICAL_TRIALS trial_result · 2019-06-03Clinical Trial Update: An Investigational Immuno-therapy Trial of Pomalidomide and Low-dose Dexamethasone With or Without Elotuzumab to Treat Refractory and Relapsed and Refractory Multiple Myeloma (ELOQUENT-3) [Phase 2]
Phase 2 trial evaluating pomalidomide and low-dose dexamethasone with or without elotuzumab in relapsed/refractory multiple myeloma complete…
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CLINICAL_TRIALS trial_result · 2019-05-31Clinical Trial Update: Study of MLN8237 in Participants With Advanced Hematological Malignancies [Phase 1]
Phase 1 study of MLN8237 in advanced hematological malignancies completed; results posted in 2019.
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FDA approval · 2019-05-30FDA Approved: MOZOBIL — Supplemental Application (Sanofi-Aventis U.S. LLC)
FDA approved a supplemental application for Mozobil (plerixafor) by Sanofi-Aventis U.S. LLC. The approval expands the indication to mobilize…
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CLINICAL_TRIALS trial_result · 2019-05-30Clinical Trial Update: Lenalidomide and Nivolumab in Treating Patients With Relapsed or Refractory Multiple Myeloma [Phase 2]
Phase 2 trial evaluating lenalidomide with nivolumab in relapsed or refractory multiple myeloma has been terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Sonidegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma [Phase 2]
Phase 2 clinical trial evaluating sonidegib and lenalidomide after stem cell transplant in patients with recurrent or refractory multiple my…
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FDA approval · 2019-05-28FDA Approved: MELPHALAN HYDROCHLORIDE — Original Application (Fosun Pharma USA Inc)
FDA approved the original application for melphalan hydrochloride (generic) supplied by Fosun Pharma USA Inc for use in treating multiple my…
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CLINICAL_TRIALS trial_result · 2019-05-17Clinical Trial Update: Positron Emission Tomography (PET) Imaging Studies With NIS Reporter [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating PET imaging with an NIS reporter in patients with myeloma and endometrial cancer; the study is term…
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CLINICAL_TRIALS trial_result · 2019-05-07Clinical Trial Update: A Study of Oral Ixazomib Citrate (MLN9708) Maintenance Therapy in Participants With Multiple Myeloma Following Autologous Stem Cell Transplant [Phase 3]
Phase 3 study evaluating ixazomib citrate as maintenance therapy after autologous stem cell transplant in multiple myeloma; results have bee…
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CLINICAL_TRIALS trial_result · 2019-05-07Clinical Trial Update: Clinical Research of Adoptive BCMA CAR-NK Cells on Relapse/Refractory MM [Phase 1, Phase 2]
Clinical trial update on adoptive BCMA CAR-NK cells for relapsed/refractory multiple myeloma across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2019-05-01Clinical Trial Update: Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies [Phase 2]
Phase 2 clinical trial evaluating BL-8040 for mobilizing donor hematopoietic stem cells to enable allogeneic transplantation in patients wit…
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CLINICAL_TRIALS trial_result · 2019-04-29Clinical Trial Update: Thalidomide to Overcome Lenalidomide Resistance After Autologous Hematopoietic Stem Cell Transplantation (HCT) [NA]
A terminated clinical trial evaluating thalidomide to overcome lenalidomide resistance after autologous stem cell transplantation in myeloma…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Study of Ibrutinib in Combination With Pomalidomide and Dexamethasone in Subjects With Relapsed/Refractory Multiple Myeloma [Phase 1, Phase 2]
Phase 1/2 trial evaluating ibritinib in combination with pomalidomide and dexamethasone for relapsed/refractory multiple myeloma; study term…
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CLINICAL_TRIALS trial_result · 2019-04-17Clinical Trial Update: Bortezomib Consolidation Trial [Phase 2]
A Phase 2 clinical trial update evaluating bortezomib as consolidation therapy in multiple myeloma has completed.
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CLINICAL_TRIALS trial_result · 2019-04-08Clinical Trial Update: Carfilzomib, Pegylated Liposomal Doxorubicin Hydrochloride, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma [Phase 1, Phase 2]
Phase 1/2 trial evaluating carfilzomib with pegylated liposomal doxorubicin and dexamethasone in relapsed or refractory multiple myeloma has…
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CLINICAL_TRIALS trial_result · 2019-04-03Clinical Trial Update: A Study to Evaluate Dara-CyBorD in Previously Untreated and Relapsed Subjects With Multiple Myeloma [Phase 2]
Phase 2 trial evaluating Dara-CyBorD in previously untreated and relapsed multiple myeloma completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-26Clinical Trial Update: Adoptive Cellular Immunotherapy Following Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma [Phase 2]
Phase 2 trial evaluating adoptive cellular immunotherapy after autologous stem cell transplantation in multiple myeloma completed with poste…
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CLINICAL_TRIALS trial_result · 2019-03-26Clinical Trial Update: Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant [Phase 1]
A Phase 1 study evaluating tremelimumab with durvalumab, high-dose chemotherapy, and autologous stem cell transplant in multiple myeloma was…
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CLINICAL_TRIALS trial_result · 2019-03-20Clinical Trial Update: Study of Tabalumab (LY2127399) in Japanese Participants With Relapsed or Refactory Multiple Myeloma [Phase 1]
Phase 1 study of tabalumab (LY2127399) in Japanese patients with relapsed or refractory multiple myeloma has been completed with results pos…
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CLINICAL_TRIALS trial_result · 2019-03-15Clinical Trial Update: Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L [Phase 2]
Phase 2 trial evaluating lenalidomide plus low-dose dexamethasone followed by stem cell collection and randomization to continued therapy or…