Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2020-02-27Clinical Trial Update: Determining the Feasibility of MLN9708 as Maintenance After Allogeneic Stem Cell Transplant for Multiple Myeloma [Phase 2]
Phase 2 trial assessing MLN9708 as maintenance therapy after allogeneic stem cell transplant in multiple myeloma; study completed with resul…
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CLINICAL_TRIALS trial_result · 2020-02-26Clinical Trial Update: Study Testing Radium-223 Dichloride in Relapsed Multiple Myeloma [Phase 1, Phase 2]
A study evaluating radium-223 dichloride in relapsed multiple myeloma was terminated; results were posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-25Clinical Trial Update: Mel vs BUCY+VP-16 Conditioning Regimen for MM Undergoing Auto-HSCT [Phase 2, Phase 3]
Phase 2/3 clinical trial comparing Mel vs BUCY+VP-16 conditioning for multiple myeloma patients undergoing autologous hematopoietic stem cel…
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FDA approval · 2020-02-21FDA Approved: ZOLEDRONIC ACID — Supplemental Application (Dr. Reddy's Laboratories Limited)
The FDA approved a supplemental application for Zoledronic acid from Dr. Reddy's Laboratories Limited, authorizing a generic product through…
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FDA approval · 2020-02-21FDA Approved: NINLARO — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for NINLARO (ixazomib) submitted by Takeda Pharmaceuticals America, Inc. The approval updates the pr…
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FDA approval · 2020-02-21FDA Approved: ZOLEDRONIC ACID — Supplemental Application (BluePoint Laboratories)
FDA approved a supplemental application for zoledronic acid submitted by BluePoint Laboratories (ANDA205279).
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CLINICAL_TRIALS trial_result · 2020-02-07Clinical Trial Update: Study Comparing Daratumumab, Lenalidomide, Bortezomib, and Dexamethasone (D-RVd) Versus Lenalidomide, Bortezomib, and Dexamethasone (RVd) in Subjects With Newly Diagnosed Multiple Myeloma [Phase 2]
Phase 2 study comparing D-RVd (daratumumab–lenalidomide–bortezomib–dexamethasone) versus RVd (lenalidomide–bortezomib–dexamethasone) in newl…
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CLINICAL_TRIALS trial_result · 2020-02-06Clinical Trial Update: Melphalan and Stem Cell Transplant Before Total-Body Irradiation and Donor Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating melphalan and stem cell transplant before total-body irradiation and donor stem cell transplant in pat…
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: PDD vs PAD to Treat Initially Diagnosed MM [Phase 4]
A Phase 4 clinical trial update for using PDD vs PAD in initially diagnosed multiple myeloma is reported, with unknown status.
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Study of Bendamustine and IXAZOMIB (MLN9708) Plus Dexamethasone in Relapsed/Refractory Multiple Myeloma [Phase 1, Phase 2]
Phase 1/2 study of bendamustine with ixazomib and dexamethasone in relapsed/refractory multiple myeloma completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: A Phase I/II Study of Mis-Matched Immune Cells (AlloStim) in Patients With Advanced Hematological Malignancy [Phase 1, Phase 2]
Phase I/II study evaluating mis-matched immune cells (AlloStim) in patients with advanced hematological malignancies; trial completed.
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT [Phase 1]
Phase 1 trial exploring a calcineurin inhibitor-free graft-versus-host disease prevention regimen after related haploidentical peripheral bl…
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Treatment With a Scheme With Low Doses of Bortezomib / Melphalan / Prednisone (MPV) in Patients With Multiple Myeloma [Phase 4]
Phase 4 clinical trial update on MPV (low-dose bortezomib/melphalan/prednisone) in multiple myeloma; the study is terminated.
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Trial of Two Stem Cell Doses To Reduce Transplant Induced Symptom Burden [Phase 2]
Phase 2 trial evaluating two stem cell dose regimens to reduce transplant-induced symptom burden in patients with multiple myeloma or primar…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Irradiation-based Myeloablative Conditioning Followed by Treg/Tcon Immunotherapy in HSCT [Phase 2]
Phase 2 clinical trial evaluating irradiation-based myeloablative conditioning followed by regulatory T cell and conventional T cell immunot…
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CLINICAL_TRIALS trial_result · 2020-01-09Clinical Trial Update: Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Participants With Previously Untreated Multiple Myeloma [Phase 3]
Phase 3 trial comparing Daratumumab, Lenalidomide, and Dexamethasone (DRd) with Lenalidomide and Dexamethasone (Rd) in previously untreated …
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Study of Ibrutinib in Combination With Bortezomib and Dexamethasone in Subjects With Relapsed/Relapsed and Refractory Multiple Myeloma [Phase 2]
Phase 2 trial evaluating the combination of ibrutinib with bortezomib and dexamethasone in relapsed/refractory multiple myeloma has complete…
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CLINICAL_TRIALS trial_result · 2019-12-20Clinical Trial Update: Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating total-body irradiation and fludarabine phosphate followed by donor peripheral blood stem cell transpla…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Trial of Three Stem Cell Mobilization Regimens for Multiple Myeloma [Phase 3]
A Phase 3 trial evaluating three stem cell mobilization regimens in patients with multiple myeloma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2019-12-13Clinical Trial Update: Ixazomib in Combination With Thalidomide - Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma [Phase 2]
Phase 2 trial updating ixazomib with thalidomide and dexamethasone in relapsed/refractory multiple myeloma has completed.
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CLINICAL_TRIALS trial_result · 2019-12-11Clinical Trial Update: MLN9708 (Ixazomib) in Combination With Panobinostat and Dexamethasone in Multiple Myeloma [Phase 1, Phase 2]
Phase 1/2 trial of Ixazomib (MLN9708) in combination with panobinostat and dexamethasone for multiple myeloma has completed with posted resu…
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CLINICAL_TRIALS trial_result · 2019-12-11Clinical Trial Update: Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial update for autologous CAR-T/TCR-T cell immunotherapy targeting multiple malignancies; current status is unknown.
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CLINICAL_TRIALS trial_result · 2019-12-09Clinical Trial Update: Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant [Phase 2]
Phase 2 trial investigating sirolimus, cyclosporine, and mycophenolate mofetil to prevent graft-versus-host disease in patients with blood c…
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CLINICAL_TRIALS trial_result · 2019-12-06Clinical Trial Update: Multinational Clinical Study Comparing Isatuximab, Pomalidomide, and Dexamethasone to Pomalidomide and Dexamethasone in Refractory or Relapsed and Refractory Multiple Myeloma Patients [Phase 3]
Phase 3 multinational trial compares isatuximab with pomalidomide and dexamethasone versus pomalidomide and dexamethasone in relapsed or ref…
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CLINICAL_TRIALS trial_result · 2019-12-06Clinical Trial Update: Apixaban for Primary Prevention of Venous Thromboembolism in Patients With Multiple Myeloma [Phase 4]
Phase 4 trial update on apixaban for primary prevention of venous thromboembolism in patients with multiple myeloma; results have been poste…