Multiple Myeloma
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma [Phase 1]
Phase 1 clinical trial evaluating CRISPR-edited allogeneic anti-BCMA CAR-T cell therapy in patients with relapsed or refractory multiple mye…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Study of 4 Bone Turnover Markers in Patients With Multiple Myeloma Treated With Intravenous Bisphosphonate in Routine Care
This clinical trial update reports on four bone turnover markers in multiple myeloma patients treated with intravenous bisphosphonates in ro…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Comparison of the Effects of Apixaban on Thrombin Generation in Patients With de Novo Multiple Myeloma [NA]
This document reports a clinical trial update examining how apixaban affects thrombin generation in patients with de novo multiple myeloma.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: PROFAST Intervention in Precursor Multiple Myeloma [NA]
A Dana-Farber Cancer Institute trial evaluating the PROFAST intervention in precursor states to multiple myeloma has completed (NCT05565638)…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study
The CREST study update shows the cardiovascular reserve evaluation trial in transplant survivors is currently active but not recruiting, spo…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Precision Medicine Study
A precision medicine clinical trial sponsored by Icahn School of Medicine at Mount Sinai is currently recruiting for multiple myeloma.
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Self-administered Subcutaneous Daratumumab in Patients With Multiple Myeloma [Phase 4]
This document provides an update on a Phase 4 clinical trial evaluating self-administered subcutaneous daratumumab for relapsed multiple mye…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Impact of an Early Warning System on the Prognosis of Patients With Hematological Malignancies Receiving Intensive Chemotherapy With or Without Hematopoietic Cell Transplantation. [NA]
This clinical trial update outlines a study evaluating whether an early warning system affects prognosis for patients with hematological mal…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: UF-KURE-BCMA CAR-T Cells in Patients With Relapsed or Refractory Multiple Myeloma [Phase 1]
This clinical trial update reports a Phase 1 study of UF-KURE-BCMA CAR-T Cells in relapsed or refractory multiple myeloma, with the study cu…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: A Single-arm Single-center Trial of Bridging GPRC5D/CD3 Bispecific Antibody Treatment With BCMA CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma [EARLY_Phase 1]
This entry describes an early-phase, single-arm, single-center trial evaluating bridging GPRC5D/CD3 bispecific antibody treatment followed b…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Mobilization of Stem Cells With AMD3100 (Plerixafor) in Combination With G-CSF in Multiple Myeloma Patients [Phase 4]
Phase 4 clinical trial completed evaluating mobilization of autologous hematopoietic stem cells using AMD3100 (plerixafor) in combination wi…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy [Phase 2]
A Phase 2 clinical trial update notes evaluation of siltuximab for treating cytokine release syndrome (CRS) and ICANS related to CAR-T cell …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Phase II Study of QLS32015 Combination Therapy in the Treatment of Multiple Myeloma [Phase 2]
Phase II clinical trial evaluating QLS32015 in combination therapy for relapsed or refractory multiple myeloma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: High Throughput Drug Sensitivity and Genomics Data in Developing Individualized Treatment in Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia [NA]
This ClinicalTrials.gov entry updates a study that uses high-throughput drug sensitivity and genomics to guide individualized treatment for …
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CLINICAL_TRIALS other · 2025-09-22Clinical Trial Update: MCARH109 Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of Multiple Myeloma [Phase 1]
This is an update on a Phase 1 clinical trial of MCARH109 CAR-T cells for multiple myeloma; the study is active but not currently recruiting…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Treatment of Primary Plasma Cell Leukaemia in Subjects Under the Age of 70 [Phase 2]
This update reports the completion of a Phase 2 clinical trial evaluating treatment for primary plasma cell leukemia in patients under 70.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of Multiple Myeloma Patients With Extramedullary Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating external beam radiation therapy in combination with talquetamab for the treatment of multiple myelo…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma [Phase 1]
Phase 1 trial evaluating CLN-619, an anti-MICA/MICB antibody, in relapsed/refractory multiple myeloma. The study is active but not recruitin…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Evaluation of a Pain Management Intervention Preparatory to a Future Pragmatic Trial, ASCENT Study [NA]
This clinical trial update reports the completion of the ASCENT pain management intervention study with results posted for a future pragmati…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Study of CM336 in Relapsed or Refractory Multiple Myeloma Patients [Phase 3]
This entry announces a Phase 3 clinical trial of CM336 for relapsed or refractory multiple myeloma that is not yet recruiting.
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients [Phase 1]
Phase 1 trial evaluating Itacitinib with high-dose posttransplantation cyclophosphamide in older patients. The study is currently ACTIVE_NOT…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Tandem Auto Stem Cell Transplant With Melphalan Followed by Melphalan and Bortezomib in Patients With Multiple Myeloma [Phase 3]
Phase 3 trial evaluating tandem autologous stem cell transplant with melphalan followed by melphalan and bortezomib in adults with multiple …
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Study of Teclistamab in Combination in Elderly Patients With Multiple Myeloma [Phase 2]
Phase 2 trial evaluating teclistamab in combination therapy in elderly patients with multiple myeloma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: A Clinical Study of BT02 in Patients With Relapsed or Refractory Hematologic Malignancies [Phase 1, Phase 2]
Biotroy Therapeutics is conducting a Phase 1/2 study of BT02 for relapsed or refractory hematologic malignancies, with recruitment not yet s…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: HEME Home Transfusion Program [NA]
Clinical trial update indicates that the HEME Home Transfusion Program is currently recruiting for hematologic conditions including leukemia…