Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-08-23Clinical Trial Update: CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell Transplantation [NA]
This clinical trial evaluated CD8 donor lymphocyte infusion for relapse or residual disease after allogeneic stem cell transplantation. The …
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CLINICAL_TRIALS research · 2012-08-17Clinical Trial Update: Total Marrow Irradiation and High-dose Melphalan for Double Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma [Phase 2]
Clinical trial update for total marrow irradiation with high-dose melphalan as conditioning before double autologous stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2012-08-09Clinical Trial Update: Low-Intensity Preparation and Allogeneic Transplant in Patients With Cancers of the Blood [Phase 2]
This entry summarizes a Phase 2 trial evaluating low-intensity conditioning followed by allogeneic stem cell transplantation for patients wi…
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CLINICAL_TRIALS trial_result · 2012-08-09Clinical Trial Update: Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB) [Phase 1, Phase 2]
Clinical trial update on a reduced-intensity preparative regimen followed by stem cell transplantation (FAB) in several hematologic malignan…
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CLINICAL_TRIALS trial_result · 2012-08-08Clinical Trial Update: Lenalidomide With or Without Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma [Phase 2]
Phase 2 clinical trial evaluating lenalidomide with or without dexamethasone in newly diagnosed multiple myeloma has completed with results …
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CLINICAL_TRIALS research · 2012-08-02Clinical Trial Update: Safety and Efficacy Study of High Dose Melphalan to Treat Multiple Myeloma [NA]
This update reports on a clinical trial evaluating high-dose melphalan for treating multiple myeloma, focusing on safety and efficacy. The p…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Pegfilgrastim (Neulasta) for Stem Cell Mobilization in Patients With Multiple Myeloma [Phase 2]
Phase 2 study evaluating pegfilgrastim (Neulasta) for stem cell mobilization in patients with multiple myeloma has completed.
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Plerixafor in Treating Patients With Multiple Myeloma Previously Treated With Lenalidomide and Planning to Undergo Autologous Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating plerixafor in multiple myeloma patients previously treated with lenalidomide who planned to undergo autologous stem…
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FDA approval · 2012-07-20FDA Approved: KYPROLIS — Original Application (Onyx Pharmaceuticals, Inc.)
The FDA approved KYPROLIS (carfilzomib) in its original application for the treatment of multiple myeloma in patients who have received at l…
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CLINICAL_TRIALS trial_result · 2012-07-20Clinical Trial Update: Dasatinib in Combination With Revlimid (and Dexamethasone) [Phase 1]
Results from a Phase 1 study of dasatinib in combination with Revlimid (lenalidomide) and dexamethasone for multiple myeloma were reported, …
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CLINICAL_TRIALS research · 2012-07-20Clinical Trial Update: VELCADE-Thalidomide-Dexamethasone (VTD) vs Thalidomide-Dexamethasone (TD) Incorporated Into Double Autotransplantation for Untreated Multiple Myeloma (MM) [Phase 3]
Phase 3 trial comparing Velcade-Thalidomide-Dexamethasone (VTD) versus Thalidomide-Dexamethasone (TD) in double autotransplantation for untr…
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CLINICAL_TRIALS trial_result · 2012-07-19Clinical Trial Update: Study of ZIO-101 in Multiple Myeloma [Phase 1, Phase 2]
The update reports the completion of a Phase 1/2 study of ZIO-101 in patients with multiple myeloma.
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CLINICAL_TRIALS trial_result · 2012-07-19Clinical Trial Update: A Phase I Trial of ZIO-101 in Hematologic Cancers [Phase 1]
This document reports the completion status of a Phase I trial evaluating ZIO-101 in hematologic cancers sponsored by Alaunos Therapeutics.
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CLINICAL_TRIALS trial_result · 2012-07-13Clinical Trial Update: EMMA-1 (Erbitux for Multiple Myeloma) [Phase 2]
EMMA-1, a Phase 2 trial of cetuximab (Erbitux) for multiple myeloma, has been terminated; no results are provided in the update.
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CLINICAL_TRIALS trial_result · 2012-07-11Clinical Trial Update: Long-Term Follow Up Study for AMD3100 Patients
Long-term follow-up data from a completed trial evaluating AMD3100 (plerixafor) in patients with multiple myeloma were reported by MD Anders…
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CLINICAL_TRIALS trial_result · 2012-07-09Clinical Trial Update: Safety Study of Dasatinib With Bortezomib (Velcade®) and Dexamethasone for Multiple Myeloma [Phase 1]
A Phase 1 safety study evaluating dasatinib in combination with bortezomib and dexamethasone for multiple myeloma was terminated, with resul…
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CLINICAL_TRIALS trial_result · 2012-07-06Clinical Trial Update: Phase I Study of Perifosine + Lenalidomide and Dexamethasone for Patients With Multiple Myeloma [Phase 1]
Phase I study of perifosine in combination with lenalidomide and dexamethasone in multiple myeloma has completed, with safety and early effi…
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CLINICAL_TRIALS trial_result · 2012-07-04Clinical Trial Update: Zoledronate With or Without Thalidomide in Treating Patients With Early Stage Multiple Myeloma [Phase 3]
Phase 3 trial evaluating zoledronate with or without thalidomide in early-stage multiple myeloma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2012-06-28Clinical Trial Update: An Open-label, Dose-escalation Safety and Tolerability Trial Assessing Anti-KIR (1-7F9) in Subjects With Multiple Myeloma [Phase 1]
A Phase 1 open-label dose-escalation study evaluating the safety and tolerability of the anti-KIR antibody 1-7F9 in patients with multiple m…
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CLINICAL_TRIALS trial_result · 2012-06-28Clinical Trial Update: Lenalidomide-Adriamycin-Dexamethasone (RAD) Induction Followed by Stem Cell Transplant in Newly Diagnosed Multiple Myeloma [Phase 2]
Phase 2 trial evaluating lenalidomide, doxorubicin (Adriamycin), and dexamethasone induction followed by stem cell transplant in newly diagn…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: Human Leukocyte Antigen (HLA) Class I Haplotype Mismatched Natural Killer Cell Infusions [Phase 1]
Phase 1 clinical trial update on HLA Class I haplotype-mismatched natural killer cell infusions for hematologic cancers, including lymphoma,…
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CLINICAL_TRIALS trial_result · 2012-06-18Clinical Trial Update: Combination High Dose Melphalan and Autologous Peripheral Blood Stem Cell (PBSC) Transplant With Bortezomib for Multiple Myeloma: A Dose and Schedule Finding Study [Phase 1, Phase 2]
This Phase 1/2 trial evaluated adding bortezomib to high-dose melphalan followed by autologous peripheral blood stem cell transplant in mult…
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CLINICAL_TRIALS trial_result · 2012-06-12Clinical Trial Update: Retrospective Survey of Re-treatment With Bortezomib
A retrospective study evaluating outcomes of patients with multiple myeloma treated again with bortezomib.
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CLINICAL_TRIALS trial_result · 2012-06-12Clinical Trial Update: Bone Marrow Transplantation in Treating Patients With Multiple Myeloma, Chronic Phase Chronic Myelogenous Leukemia, or Agnogenic Myeloid Metaplasia [Phase 2]
Phase 2 clinical trial update on bone marrow transplantation for patients with multiple myeloma, chronic myeloid leukemia (chronic phase), o…
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CLINICAL_TRIALS trial_result · 2012-06-08Clinical Trial Update: Treatment With Velcade (Bortezomib) Plus Dexamethasone (VD) or VD Plus Cyclophosphamide or VD Plus Lenalidomide in Patients With Multiple Myeloma Stabilized After 4 Cycles of VD [Phase 2]
Phase 2 study evaluating Velcade (bortezomib) plus dexamethasone, with or without cyclophosphamide or lenalidomide, in multiple myeloma pati…