Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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FDA approval · 2014-09-12FDA Approved: THALOMID — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for THALOMID (thalidomide) submitted by Celgene Corporation, resulting in an expanded indication.
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FDA approval · 2014-09-12FDA Approved: POMALYST — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for POMALYST (pomalidomide) filed by Celgene Corporation. The action updates the drug’s labeling to …
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CLINICAL_TRIALS trial_result · 2014-09-12Clinical Trial Update: Evaluation of the Drug Plerixafor in Combination With Chemotherapy and G-CSF for Stem Cell Collection [Phase 2]
A Phase 2 clinical trial evaluating plerixafor in combination with chemotherapy and G-CSF for stem cell collection in patients with multiple…
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CLINICAL_TRIALS trial_result · 2014-09-11Clinical Trial Update: Safety and Tolerability Study of SNS01-T in Relapsed or Refractory B Cell Malignancies (Multiple Myeloma, B Cell Lymphoma, or Plasma Cell Leukemia (PCL) [Phase 1, Phase 2]
Phase 1/2 safety and tolerability study of SNS01-T in relapsed or refractory B-cell malignancies sponsored by Senesco Technologies. The tria…
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CLINICAL_TRIALS trial_result · 2014-09-11Clinical Trial Update: Investigation of the Cylex® ImmuKnow® Assay
A completed clinical trial investigating the Cylex ImmuKnow immune function assay across several hematologic diseases.
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CLINICAL_TRIALS trial_result · 2014-09-10Clinical Trial Update: Combination Study of Revlimid®, Velcade® Dexamethasone and Doxil® (RVDD)for Newly Diagnosed Multiple Myeloma [Phase 1, Phase 2]
This clinical trial update reports results from a phase 1/2 study evaluating the combination of Revlimid (lenalidomide), Velcade (bortezomib…
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CLINICAL_TRIALS trial_result · 2014-09-04Clinical Trial Update: PTK/ZK as Post Transplant Maintenance Therapy in Patients With Multiple Myeloma [Phase 2]
This Phase 2 trial evaluated PTK/ZK as post-transplant maintenance therapy in patients with multiple myeloma; the study was terminated and r…
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: A Phase II Study of Dasatinib in the Treatment of Relapsed or Plateau Phase Multiple Myeloma [Phase 2]
A Phase II clinical trial update evaluating dasatinib for relapsed or plateau-phase multiple myeloma, with results posted in 2014.
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CLINICAL_TRIALS withdrawal · 2014-08-27Clinical Trial Update: A Single Agent Study to Evaluate the Overall Response Rate, Safety and Tolerability of Orally Administered Vemurafenib [Phase 1, Phase 2]
A Phase 1/2 single-agent trial of vemurafenib in multiple myeloma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-08-25Clinical Trial Update: Imaging Young Myeloma (IMAgerie JEune Myélome) [Phase 3]
A Phase 3 imaging trial for multiple myeloma conducted by Nantes University Hospital has completed.
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: PK Study of Melphalan HCL & Alkeran for Injection of MA Conditioning in MM Patients of Autologous Transplantation [Phase 2]
Phase 2 PK study evaluating melphalan HCL and Alkeran for MA conditioning in autologous transplantation for multiple myeloma completed with …
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: Oncaspar/Doxil/Decadron in Patients With Refractory Lymphoid Malignancies [Phase 2]
Phase 2 trial evaluating Oncaspar (pegaspargase), Doxil (liposomal doxorubicin), and Decadron (dexamethasone) in refractory lymphoid maligna…
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CLINICAL_TRIALS trial_result · 2014-08-19Clinical Trial Update: Bortezomib, Lenalidomide and Dexamethasone Combination Therapy in Patients With Newly Diagnosed Multiple Myeloma [Phase 1, Phase 2]
This clinical trial update reports Phase 1/2 results for a triple-drug combination (bortezomib, lenalidomide, dexamethasone) in newly diagno…
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CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Study of Bortezomib and Dexamethasone With or Without Cyclophosphamide in Patients With Relapsed or Not Controllable Multiple Myeloma [Phase 3]
Phase 3 trial evaluating bortezomib and dexamethasone with or without cyclophosphamide in relapsed or uncontrolled multiple myeloma; results…
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CLINICAL_TRIALS trial_result · 2014-08-11Clinical Trial Update: RAD001 and Lenalidomide in the Treatment of Subjects With Relapsed and Relapsed/Refractory Multiple Myeloma [Phase 1]
Phase 1 trial evaluating RAD001 (everolimus) in combination with lenalidomide in subjects with relapsed and relapsed/refractory multiple mye…
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CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: IV Busulfan Plus Bortezomib Conditioning Regimen for Second Autologous Stem Cell Transplant in Multiple Myeloma Patients [Phase 2]
Phase 2 results update for IV busulfan plus bortezomib conditioning before a second autologous stem cell transplant in multiple myeloma pati…
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: Filgrastim With or Without Plerixafor in Treating Patients With Multiple Myeloma Previously Treated With Lenalidomide [Phase 3]
A Phase 3 trial evaluating filgrastim with or without plerixafor in patients with refractory multiple myeloma previously treated with lenali…
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: American Ginseng in Treating Patients With Fatigue Caused by Cancer [Phase 3]
A phase 3 trial evaluating American ginseng for cancer-related fatigue has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2014-08-05Clinical Trial Update: Effect of Combination of Bortezomib/Dexamethasone/Zoledronic Acid on Bone Disease in Patients With Multiple Myeloma Relapsed After 1-3 Prior Lines of Therapy [Phase 2]
Phase 2 trial evaluating the combination of bortezomib, dexamethasone, and zoledronic acid for bone disease in relapsed multiple myeloma; re…
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CLINICAL_TRIALS trial_result · 2014-07-23Clinical Trial Update: Bortezomib and Thalidomide in Treating Patients With Newly Diagnosed Stage II or Stage III Multiple Myeloma [Phase 2]
A Phase 2 trial evaluating the combination of bortezomib and thalidomide in newly diagnosed Stage II or Stage III multiple myeloma; results …
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CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: An Dose Escalation Study of BIBF 1120 Administered in Patients With Relapsed or Refractory Multiple Myeloma [Phase 1]
Phase 1 dose-escalation study of BIBF 1120 (nintedanib) in patients with relapsed or refractory multiple myeloma has completed.
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CLINICAL_TRIALS withdrawal · 2014-07-11Clinical Trial Update: Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma [Phase 2]
A Phase 2 trial evaluating a carfilzomib/SAHA combination with high-dose gemcitabine/busulfan/melphalan and autologous stem cell transplant …
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: High Dose Sequential Therapy and Autologous Stem Cell Rescue for Multiple Myeloma [Phase 2]
A Phase 2 trial at Duke University evaluating high-dose sequential therapy with autologous stem cell rescue for multiple myeloma has complet…
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: A Study of Avastin (Bevacizumab) in Patients With Multiple Myeloma [Phase 2]
A Phase 2 study of Avastin (bevacizumab) in patients with multiple myeloma has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2014-07-01Clinical Trial Update: A Safety and Efficacy Study of CNTO 328 in Patients With B-Cell Non-Hodgkin's Lymphoma, Multiple Myeloma, or Castleman's Disease [Phase 1]
This document reports the completion of a Phase 1 safety and efficacy study of CNTO-328 (siltuximab) in patients with B-cell non-Hodgkin lym…