Multiple Myeloma
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Covid-19 Vaccine Responsiveness in MM and Waldenstrom
Completed clinical trial update examining how patients with multiple myeloma and Waldenström macroglobulinemia respond to COVID-19 vaccinati…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: A Multicenter Open Label Phase II Study of Pomalidomide and Cyclophosphamide and Dexamethasone in Relapse/Refractory Multiple Myeloma Patients Who Were First Treated Within the IFM/DFCI 2009 Trial (PCD) [Phase 2]
A multicenter open-label Phase II study evaluating pomalidomide, cyclophosphamide, and dexamethasone in relapsed/refractory multiple myeloma…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: A Safety Study of Lenalidomide in Previously Untreated Adult Multiple Myeloma Patients Who Are Not Eligible for Transplant
This entry notes a safety-focused clinical trial of lenalidomide in adults with previously untreated multiple myeloma who are not eligible f…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Descartes-15 for Patients With Relapsed/Refractory Multiple Myeloma [Phase 1]
A Phase 1 clinical trial of Descartes-15 for relapsed or refractory multiple myeloma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Home Based Daratumumab Administration for Patients With Multiple Myeloma [Phase 4]
Phase 4 study update on home-based administration of daratumumab for multiple myeloma, with the trial completed and results posted.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Determining The Impact Of Distance Reiki On Patient Reported QOL And Immunity Among Multiple Myeloma Patients [NA]
A completed clinical trial assessing whether distance Reiki improves quality of life and immune function in multiple myeloma patients underg…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: High Dose Carfilzomib for Newly Diagnosed Myeloma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating high-dose carfilzomib in newly diagnosed multiple myeloma has completed enrollment with results posted.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Value of Macrophage-Colony Stimulating Factor as a New Marker of Bone Lesions in Multiple Myeloma [NA]
A completed clinical trial evaluating macrophage-colony stimulating factor as a biomarker for bone lesions in patients with multiple myeloma…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer [Phase 1]
A Phase 1 trial evaluating natural killer cell therapy in combination with Interleukin-2 and the TGF-beta receptor I inhibitor vactosertib f…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Belantamab Mafadotin Maintenance Therapy After Salvage Autologous Hematopoietic Cell Transplantation in Patients With Relapse Refractory Multiple Myeloma [Phase 1]
A Phase 1 trial of belantamab mafodotin as maintenance therapy after salvage autologous hematopoietic cell transplantation in relapse/refrac…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: ON 123300 (Narazaciclib) and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma [Phase 1, Phase 2]
A Phase 1/2 trial of Narazaciclib in combination with dexamethasone for relapsed and/or refractory multiple myeloma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Stem Cell Transplantation for Patients With Multiple Myeloma [Phase 1]
A Phase 1 trial evaluating stem cell transplantation for patients with multiple myeloma has completed.
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating nivolumab in patients with hematologic malignancies after CAR-T therapy; results have been posted with the study cu…
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma [Phase 1]
Phase 1 clinical trial evaluating the combination of selinexor, carfilzomib, and dexamethasone in relapsed or refractory multiple myeloma ha…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Testing GSK2636771 as a Potential Targeted Treatment in Cancers With PTEN Genetic Changes (MATCH-Subprotocol N) [Phase 2]
Phase 2 MATCH subprotocol update evaluating GSK2636771 for cancers with PTEN genetic changes; results were posted in 2025.
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating reduced-intensity conditioning before allogeneic donor stem cell transplantation in patients with high-risk hematol…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Scalp Cooling to Prevent Hair Loss in Patients Undergoing Stem Cell Transplantation for Multiple Myeloma [NA]
This trial evaluated scalp cooling to prevent hair loss in patients undergoing stem cell transplantation for multiple myeloma, with results …
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: To Assess the Safety and Tolerability of INCB000928 in Participants With Myelodysplastic Syndromes or Multiple Myeloma [Phase 1, Phase 2]
This clinical trial update reports the termination of a Phase 1/2 study of INCB000928 in myelodysplastic syndromes and multiple myeloma, wit…
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: A Study of Colesevelam for Lenalidomide-Associated Diarrhea [Phase 2]
A Phase 2 study evaluating colesevelam for lenalidomide-associated diarrhea in multiple myeloma patients has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: High Dose Ascorbic Acid for Plasma Cell Disorders [Phase 1]
Phase 1 trial evaluating high-dose ascorbic acid (vitamin C) in multiple myeloma has completed.
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Testing GSK2636771 as a Potential Targeted Treatment in Cancers With PTEN Loss of Expression (MATCH-Subprotocol P) [Phase 2]
Phase 2 trial update evaluating GSK2636771 in cancers with PTEN loss under the MATCH program; the study is active but not recruiting and res…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: A Study of Modakafusp Alfa on Adult Participants With Relapsed/Refractory Multiple Myeloma [Phase 1, Phase 2]
This clinical trial update reports results for Modakafusp Alfa in adults with relapsed/refractory multiple myeloma. The Phase 1/2 study has …
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Isa-Pom-Dex in Elderly/Frail Subjects With RRMM [Phase 2]
A Phase 2 trial of isatuximab-pomalidomide-dexamethasone (Isa-Pom-Dex) in elderly or frail patients with relapsed/refractory multiple myelom…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Feladilimab (GSK3359609) in Participants With RRMM [Phase 1, Phase 2]
A sub-study of belantamab mafodotin in combination with feladilimab in relapsed/refractory multiple myeloma is being conducted in Phase 1/Ph…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: VOB560-MIK665 Combination First in Human Trial in Patients With Hematological Malignancies (Relapsed/Refractory Non-Hodgkin Lymphoma, Relapsed/Refractory Acute Myeloid Leukemia, or Relapsed/Refractory Multiple Myeloma) [Phase 1]
This update reports termination of the first-in-human Phase 1 trial of the VOB560-MIK665 combination in relapsed/refractory hematologic mali…