Multiple Myeloma

• CLINICAL_TRIALS trial_result · 2025-06-11
  Clinical Trial Update: All Japanese Population: Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma [Phase 3]

  A Phase 3 trial comparing belantamab mafodotin plus pomalidomide and dexamethasone versus bortezomib plus pomalidomide and dexamethasone in …

• CLINICAL_TRIALS trial_result · 2025-06-06
  Clinical Trial Update: Pomalidomide in Combination With Low-dose Dexamethasone or Pomalidomide in Combination With Low-dose Dexamethasone and Daratumumab in Subjects With Relapsed or Refractory Multiple Myeloma Following Lenalidomide-based Therapy in the First or Second Line Setting [Phase 2]

  This Phase 2 trial evaluating pomalidomide with low-dose dexamethasone, with or without daratumumab, in relapsed or refractory multiple myel…

• CLINICAL_TRIALS trial_result · 2025-06-05
  Clinical Trial Update: Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation [Phase 1, Phase 2]

  A Phase 1/2 clinical trial evaluating Palifermin (Kepivance) in patients undergoing unrelated donor allogeneic hematopoietic cell transplant…

• CLINICAL_TRIALS trial_result · 2025-06-05
  Clinical Trial Update: Doxil/Caelyx BE Study [Phase 1]

  Phase 1 bioequivalence study completion for Doxil/Caelyx in ovarian cancer, Kaposi sarcoma, multiple myeloma, and metastatic breast cancer.

• CLINICAL_TRIALS trial_result · 2025-06-04
  Clinical Trial Update: Ixazomib Citrate, Lenalidomide, Dexamethasone, and Daratumumab in Treating Patients With Newly Diagnosed Multiple Myeloma [Phase 2]

  A Phase 2 clinical trial evaluates a quadruplet regimen of ixazomib, lenalidomide, dexamethasone, and daratumumab in newly diagnosed multipl…

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• CLINICAL_TRIALS trial_result · 2025-05-30
  Clinical Trial Update: First In Human (FIH) Study of REGN5459 in Adult Patients With Relapsed or Refractory Multiple Myeloma (MM) [Phase 1, Phase 2]

  This clinical trial update notes the completion of the first-in-human Phase 1/2 study of REGN5459 in adults with relapsed or refractory mult…

• CLINICAL_TRIALS trial_result · 2025-05-30
  Clinical Trial Update: Telehealth Exercise Intervention to Improve Physical Function and Frailty in Multiple Myeloma Survivors [NA]

  Completed study evaluating a telehealth exercise program to improve physical function and reduce frailty in multiple myeloma survivors.

• CLINICAL_TRIALS trial_result · 2025-05-28
  Clinical Trial Update: A Ph1/2 Study of EMB-06 in Participants With Relapsed or Refractory Myeloma [Phase 1, Phase 2]

  This clinical trial update reports termination of a Phase 1/2 study of EMB-06 for relapsed or refractory multiple myeloma.

• CLINICAL_TRIALS trial_result · 2025-05-25
  Clinical Trial Update: Safety and Efficacy Study of OPC-415 in Patients With Relapsed and/or Refractory Multiple Myeloma [Phase 1, Phase 2]

  Safety and efficacy study of OPC-415 in relapsed or refractory multiple myeloma is in Phase 1/2. The trial is currently ACTIVE_NOT_RECRUITIN…

• CLINICAL_TRIALS trial_result · 2025-05-23
  Clinical Trial Update: Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma [Phase 2]

  Phase 2 trial evaluating the efficacy and safety of bb2121 in relapsed and refractory multiple myeloma has completed with results posted.

• CLINICAL_TRIALS trial_result · 2025-05-23
  Clinical Trial Update: A Study of Daratumumab With the Addition of Recombinant Human Hyaluronidase (rHuPH20) for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma [Phase 1]

  A Phase 1 trial evaluating the addition of recombinant human hyaluronidase (rHuPH20) to daratumumab for relapsed or refractory multiple myel…

• CLINICAL_TRIALS trial_result · 2025-05-20
  Clinical Trial Update: A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma [Phase 3]

  This Phase 3 trial compares JNJ-68284528, a BCMA-directed CAR-T therapy, with pomalidomide-bortezomib-dexamethasone (PVd) or daratumumab-pom…

• CLINICAL_TRIALS trial_result · 2025-05-20
  Clinical Trial Update: A Study to Learn About the Effectiveness of the Medicine Called Elranatamab in People With Relapsed Refractory Multiple Myeloma as Compared With Standard of Care Therapies

  This clinical trial update notes the completion of a study evaluating the effectiveness of elranatamab in relapsed/refractory multiple myelo…

• CLINICAL_TRIALS trial_result · 2025-05-18
  Clinical Trial Update: Belantamab Mafodotin, Lenalidomide, and Daratumumab for the Treatment of Relapsed, Refractory, or Previously Untreated Multiple Myeloma [Phase 1]

  Phase 1 trial evaluating a triple combination of belantamab mafodotin, lenalidomide, and daratumumab for relapsed/refractory or previously u…

• CLINICAL_TRIALS trial_result · 2025-05-16
  Clinical Trial Update: Study to Determine Recommended Phase 2 Dose of Intravenous (IV) Eftozanermin Alfa in Combination With IV or Subcutaneous (SC) Bortezomib and Oral Dexamethasone Tablet and to Assess Change in Disease Symptoms in Adult Participants With Relapsed or Refractory Multiple Myeloma [Phase 1]

  A Phase 1 trial evaluating eftozanermin alfa in combination with bortezomib and dexamethasone for relapsed or refractory multiple myeloma ha…

• CLINICAL_TRIALS trial_result · 2025-05-15
  Clinical Trial Update: RAPA-201 T Cell Therapy for Relapsed, Refractory Multiple Myeloma [Phase 2]

  Phase 2 trial of RAPA-201 T Cell Therapy for relapsed and refractory multiple myeloma has completed.

• CLINICAL_TRIALS trial_result · 2025-05-13
  Clinical Trial Update: Lenalidomide Plus Melphalan as a Preparative Regimen for Autologous Stem Cell Transplantation in Relapsed Multiple Myeloma: A Phase 1 / 2 Study [Phase 1, Phase 2]

  Phase 1/2 results for lenalidomide plus melphalan as a preparative regimen for autologous stem cell transplantation in relapsed multiple mye…

• CLINICAL_TRIALS trial_result · 2025-05-13
  Clinical Trial Update: Fluoroquinolone Resistance Prevalence Study

  A clinical trial investigating fluoroquinolone resistance prevalence was terminated.

• CLINICAL_TRIALS trial_result · 2025-05-11
  Clinical Trial Update: A Study of the Safety, Tolerability and Effectiveness of EZM0414 (IPN60210) Investigative Product in Participants With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B Cell Lymphoma [Phase 1]

  Epizyme's Phase 1 study of EZM0414 (IPN60210) in relapsed/refractory multiple myeloma and relapsed/refractory diffuse large B-cell lymphoma …

• CLINICAL_TRIALS trial_result · 2025-05-09
  Clinical Trial Update: Japan Expansion Cohort: Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma [Phase 3]

  Phase 3 Japan expansion cohort update comparing Belantamab Mafodotin with Bortezomib and Dexamethasone versus Daratumumab with Bortezomib an…

• CLINICAL_TRIALS trial_result · 2025-05-02
  Clinical Trial Update: Study of Magrolimab Combinations in Patients With Relapsed/Refractory Multiple Myeloma [Phase 2]

  Phase 2 study of magrolimab combinations in relapsed/refractory multiple myeloma was terminated; results have been posted.

• CLINICAL_TRIALS trial_result · 2025-05-02
  Clinical Trial Update: Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study

  This completed clinical trial (NCT05053100) investigates the risk of blood clots and bleeding in patients with hematologic cancers.

• CLINICAL_TRIALS trial_result · 2025-05-01
  Clinical Trial Update: Melphalan Hydrochloride in Treating Participants With Newly-Diagnosed Multiple Myeloma Undergoing Donor Stem Cell Transplantation [Phase 1, Phase 2]

  A Phase 1/Phase 2 clinical trial evaluated melphalan hydrochloride in patients with newly diagnosed multiple myeloma undergoing donor stem c…

• CLINICAL_TRIALS trial_result · 2025-04-30
  Clinical Trial Update: Carfilzomib, Pomalidomide, and Dexamethasone in Treating Patients With High-Risk Multiple Myeloma [Phase 2]

  A Phase 2 trial evaluating the combination of carfilzomib, pomalidomide, and dexamethasone in high-risk multiple myeloma; the study is curre…

• CLINICAL_TRIALS trial_result · 2025-04-29
  Clinical Trial Update: Exercise Prescription for the Improvement of Quality of Life in Elderly Patients With Multiple Myeloma [NA]

  A completed clinical trial evaluating an exercise program to improve quality of life in older adults with multiple myeloma.