Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma [Phase 1]
Phase 1 clinical trial evaluating an imaging agent, 89Zr-DFO-YS5, for detecting CD46-positive malignancies in multiple myeloma. The study is…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM) [Phase 2]
This document provides a status update on a Phase 2 clinical trial evaluating belantamab mafodotin in combination with standard of care for …
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Sleep Apnea in Patients With MGUS and MM
This clinical trial update describes an ongoing study evaluating sleep apnea in patients with multiple myeloma and monoclonal gammopathy of …
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM) [Phase 2]
This clinical trial update describes a Phase 2 platform study of belantamab mafodotin as monotherapy and in combination for relapsed/refract…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Personalized NK Cell Therapy in CBT [Phase 2]
A Phase 2 trial from MD Anderson is evaluating personalized NK cell therapy across several hematologic cancers. The study is currently recru…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Fenofibrate Role in the Prophylaxis From Peripheral Neuropathy Induced by Bortezomib, Lenalidomide and Dexamethasone (VRd) Protocol in the Treatment of Patients With Multiple Myeloma (MM) [Phase 4]
This Phase 4 clinical trial investigates whether Fenofibrate can prevent peripheral neuropathy induced by VRd (bortezomib, lenalidomide, dex…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Siltuximab to Decrease Symptom Burden After Autologous Stem Cell Transplantation for Patients With Multiple Myeloma and AL Amyloidosis [Phase 2]
A Phase 2 clinical trial evaluating whether siltuximab can reduce symptom burden after autologous stem cell transplantation in patients with…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With TSC1 or TSC2 Genetic Changes (MATCH - Subprotocol M) [Phase 2]
A phase 2 MATCH subprotocol M trial update evaluating MLN0128 (TAK-228) as a targeted treatment for cancers with TSC1 or TSC2 genetic change…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Testing LOXO-101 as Potentially Targeted Treatment in Cancers With NTRK Genetic Changes (MATCH - Subprotocol Z1E) [Phase 2]
This update describes a Phase 2 MATCH subprotocol evaluating larotrectinib (LOXO-101) in cancers with NTRK gene alterations; the trial statu…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: A Study of TTI-622 in Combination With Daratumumab Hyaluronidase-fihj in People With Multiple Myeloma [Phase 1]
This update describes an open Phase 1 trial evaluating TTI-622 in combination with Daratumumab Hyaluronidase-fihj for multiple myeloma, curr…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I) [Phase 2]
Phase 2 MATCH subprotocol Z1I study evaluating AZD1775 (adavosertib) as a targeted treatment for cancers with BRCA genetic changes. The tria…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With mTOR Genetic Changes (MATCH - Subprotocol L) [Phase 2]
Phase 2 MATCH subprotocol L clinical trial evaluating MLN0128 (TAK-228) for cancers with mTOR genetic changes; status is ACTIVE_NOT_RECRUITI…
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Novel Combination of Belantamab Mafodotin and Elotuzumab to Enhance Therapeutic Efficacy in Multiple Myeloma [Phase 1, Phase 2]
The document announces a planned Phase 1/2 clinical trial evaluating the combination of belantamab mafodotin and elotuzumab for multiple mye…
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Two Step Haplo With Radiation Conditioning [Phase 2]
Phase 2 clinical trial update describing two-step haploidentical transplantation with radiation conditioning for hematologic diseases, curre…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma [Phase 1]
Phase 1 clinical trial investigating radioimmunotherapy with 111In/225Actinium-DOTA-daratumumab for relapsed/refractory multiple myeloma is …
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Subcutaneous Daratumumab Administration in the Thigh Vs Abdomen in Plasma Cell Disorders [Phase 1, Phase 2]
A Phase 1/2 clinical trial is comparing subcutaneous daratumumab administration in the thigh versus the abdomen for plasma cell disorders, c…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL [Phase 1]
Phase 1 clinical trial update for Kappa-CD28 T lymphocytes in chronic lymphocytic leukemia, B-cell lymphoma, and multiple myeloma. The study…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Isatuximab in Participants With RRMM [Phase 1, Phase 2]
Clinical trial update for a sub-study of belantamab mafodotin in combination with isatuximab for relapsed/refractory multiple myeloma (Phase…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Family Study of Lymphoproliferative Disorders
A Mayo Clinic-led clinical trial is a family study investigating lymphoproliferative disorders, currently in the recruitment phase.
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant. [Phase 1]
Phase 1 study evaluating Captisol-enabled melphalan pharmacokinetics in patients with multiple myeloma or AL amyloidosis undergoing autologo…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM [Phase 2]
Phase 2 clinical trial evaluating a quadruple combination of daratumumab, carfilzomib, pomalidomide, and dexamethasone for multiple myeloma;…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Immunoglobulin Stopping or Extension (Stop Ig) [Phase 2, Phase 3]
Clinical trial update for the Stop Ig study, assessing whether antibiotic therapy or immunoglobulin use affects infection management and dec…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Dosing Immunoglobulin (Dose Ig) [Phase 2, Phase 3]
A Monash University trial is testing antibiotic therapy or intravenous immunoglobulin dosing to prevent infections in hematologic cancer pat…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT) [Phase 2, Phase 3]
A hematology platform trial (RATIONAL-PT) is evaluating the roles of antibiotic therapy or immunoglobulin for infections in patients with he…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: ERd Combination Treatment in Newly Diagnosed Multiple Myeloma [Phase 2]
A Phase 2 clinical trial update for an ERd (elotuzumab, lenalidomide, dexamethasone) combination as initial therapy in newly diagnosed multi…