Motor Neuron Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers [NA]
The update notes ongoing natural history studies using electrical impedance myography in neuromuscular disorders and in healthy volunteers, …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Investigational Use of Neuromuscular Ultrasound
An ongoing clinical trial investigates investigational neuromuscular ultrasound for muscular dystrophy and peripheral neuropathy, with recru…
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CLINICAL_TRIALS other · 2026-04-17Clinical Trial Update: Functional Outcomes and Control Using Synchron BCI - Canada [NA]
Clinical trial update for a Synchron brain-computer interface in Canada, focusing on functional outcomes and control for individuals with am…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Functional Outcomes and Control Using Synchron BCI - Australia [NA]
Clinical trial update for Synchron's brain-computer interface device in Australia; the study targets neurologic disorders and is currently n…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study of Inherited Neurological Disorders
An NINDS-sponsored clinical trial is currently recruiting to study inherited neurological disorders affecting motor neurons and muscles.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Impact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealth
This clinical trial update from TidalHealth investigates the relationship between physical functioning and patient-reported outcomes in amyo…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
This clinical trial update describes the HSPseq Genomic Sequencing Initiative at Boston Children's Hospital to study genomic sequencing in h…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: MND Together: Phase 1
Phase 1 clinical trial update for MND Together, sponsored by the University of Sheffield; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Healing ALS Registry Observational Study (HAROS)
HAROS is an ongoing observational registry for amyotrophic lateral sclerosis and related motor neuron diseases. Recruitment is currently ope…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
This clinical trial update describes the Target ALS biomarker study investigating longitudinal biofluids, clinical measures, and at-home ass…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: ALS/MND Natural History Study Data Repository
Clinical trial update announcing a natural history data repository study for ALS and related motor neuron diseases, with recruitment ongoing…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Digital App for Speech & Health Monitoring
A Clinical Trial Update indicates a University of Edinburgh digital app for speech and health monitoring is currently recruiting participant…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their Families [NA]
This clinical trial evaluates the impact of long-term ventilation support on quality of life for people with amyotrophic lateral sclerosis a…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Patients With ALS and Other Motor Disorders Will be Treated With Mesenchymal Cell Exosome Solution [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating a Mesenchymal Cell Exosome Solution in patients with amyotro…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Dose-Escalation, Safety and Pharmacokinetic Study of IC14 in Motor Neurone Disease [Phase 1]
Phase 1 dose-escalation study evaluating safety, tolerability and pharmacokinetics of IC14 in motor neuron disease/ALS; the trial has comple…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Telehealth in MND-Research (TIM-R): A Research Database for MND
TIM-R is a telehealth research database for motor neuron disease that is currently recruiting.
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CLINICAL_TRIALS withdrawal · 2025-08-17Clinical Trial Update: IC14 for Treatment of Amyotrophic Lateral Sclerosis [Phase 2]
A Phase 2 clinical trial of IC14 for amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Safety of Intrathecal Riluzole in Patients With Amyotrophic Lateral Sclerosis [Phase 1]
Phase 1 clinical trial evaluating the safety of intrathecal riluzole in people with amyotrophic lateral sclerosis; the study is not yet recr…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices [NA]
A feasibility study of Neuralink's robotically implanted brain-computer interface to control external devices in people with tetraplegia and…
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Study to Explore the Role of Gut Flora in ALS
This clinical trial evaluating the role of gut flora in amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: An Open Label Extension Study of Monepantel in Individuals With Motor Neurone Disease [Phase 1]
Open-label extension Phase 1 trial of Monepantel in individuals with motor neuron disease has completed.
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Creation of a Clinical Database for the Study of Phenotypic Variability in Motor Neuron Diseases
This update describes the creation of a clinical database to study phenotypic variability in motor neuron diseases, including amyotrophic la…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis
This clinical trial update notes a biomarker-driven study aimed at dissecting ALS phenotypes is currently recruiting, including conditions s…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: The Study Evaluating the Improvement of Nutritional Status and Frailty With Silkworm Pupa Powder Among Patients With Motor Neuron Disease [NA]
A clinical trial update shows recruitment is ongoing for a study evaluating silkworm pupa powder to improve nutritional status and frailty i…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
The Phase 2 Meridian trial evaluating pegcetacoplan in adults with amyotrophic lateral sclerosis was terminated; results have been posted.