Monkeypox
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: A Study Evaluating the Safety and Immunogenicity of MVA Strain Monkeypox Attenuated Live Vaccine [Phase 1]
A Phase 1 study evaluating safety and immunogenicity of an MVA-based monkeypox attenuated live vaccine; currently recruiting.
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Evaluation of Effectiveness and Safety of LC16m8 Mpox Vaccine in the Democratic Republic of Congo (DRC)
A clinical trial update describes evaluating the effectiveness and safety of the LC16m8 Mpox Vaccine in the Democratic Republic of Congo, wi…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Efficacy/Effectiveness, Safety, and Immunogenicity of LC16m8 Mpox Vaccine in Colombia [Phase 3]
This document provides an update on a Phase 3 trial in Colombia evaluating the efficacy, safety, and immunogenicity of the LC16m8 Mpox vacci…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Tecovirimat for Treatment of Monkeypox Virus - Study Extension Providing Standard of Care Only
A study extension of tecovirimat for monkeypox has completed, with the extension providing standard-of-care treatment only.
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Phase 3 Infant Safety & Immunogenicity Trial of MVA-BN® in DRC [Phase 3]
Phase 3 infant safety and immunogenicity trial of the MVA-BN smallpox vaccine for monkeypox vaccination in the Democratic Republic of Congo …
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: An Immunogenicity and Safety Trial of MVA-BN in Adults Living With HIV for the Prevention of Mpox Infection, in Kinshasa, DRC [Phase 2]
Phase 2 clinical trial update evaluating the MVA-BN vaccine to prevent Mpox infection in adults living with HIV in Kinshasa, DRC; the study …
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Morbidity, Mortality And Risk Factors of Mpox in HIV Negative High Risk Sexual Health Clinic Attenders and People Living With HIV
A completed clinical trial evaluating morbidity, mortality, and risk factors of monkeypox (mpox) in HIV-negative high-risk individuals and p…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Epidemiological and Clinical Characteristics of Human Mpox Outbreak in Equateur Province in the Democratic Republic of Congo (Part2)
A clinical trial update describing an observational study of the epidemiology and clinical characteristics of the human Mpox outbreak in Equ…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Epidemiological and Clinical Characteristics of Mpox Outbreak in Equateur, the DR Congo (Part1)
This clinical trial update describes an epidemiological and clinical characterization study of the Monkeypox outbreak in Equateur, DR Congo,…
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CLINICAL_TRIALS research · 2025-07-06Clinical Trial Update: Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster RCT [Phase 4]
A Phase 4 cluster randomized trial is evaluating a smallpox vaccine for post-exposure prophylaxis in mpox (monkeypox) exposures.
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Epidemiological and Clinical Characteristics of Human Mpox Outbreak in Equateur Province in the Democratic Republic of Congo (Part3)
A clinical trial update on the epidemiology and clinical characteristics of mpox in Equateur Province, DRC, with current status indicating e…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Evaluation of Long-term Immunogenicity of a Boost Dose of MVA-BN Vaccine
This clinical trial update indicates recruitment for a study evaluating the long-term immunogenicity of a booster dose of the MVA-BN vaccine…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Monkeypox, Biology, Outcome, Transmission and Epidemiology -Prospective Follow-up of High-risk Contacts
This completed prospective study followed high-risk contacts of mpox cases to evaluate biology, outcomes, transmission, and epidemiology.
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Epidemiological and Pathophysiological Insights Through a Cross-sectional Survey (EPIC)
The EPIC cross-sectional study is currently recruiting to investigate the epidemiology and pathophysiology of mpox (monkeypox).
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Assessment of the Efficacy and Safety of Tecovirimat in Patients With Monkeypox Virus Disease [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of tecovirimat in patients with monkeypox. The study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: European Trial Into Mpox Infection [Phase 4]
This update reports a Phase 4 European clinical trial investigating mpox infection (Monkeypox), currently in recruitment.
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Mpox Comprehensive Assessment for Responsive Immunisation in Emergency Outbreaks [NA]
A clinical trial evaluating comprehensive assessment for responsive immunisation against Monkeypox during emergency outbreaks; currently rec…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV
A clinical trial investigating virologic and immunologic characteristics of severe monkeypox in people with advanced HIV.
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Characterization of Vaccine-induced Responses Against Monkeypox (MoVIHvax) An Observational Prospective Cohort Study
An observational prospective cohort study to characterize immune responses induced by the MoVIHvax Monkeypox vaccine, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Tecovirimat (ST-246) Treatment for Orthopox Virus Exposure
Clinical trial update for the antiviral Tecovirimat (ST-246) used to treat exposure to orthopoxviruses, including smallpox and monkeypox; th…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: DiagRaMIE Mpox Virus-RDC for the Diagnostic of Monkeypox
Clinical trial update for the DiagRaMIE Mpox Virus-RDC diagnostic for Monkeypox, currently NOT_YET_RECRUITING.
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EMA guidance · 2024-10-25Fostering regulatory collaboration to improve access to mpox medicines
Global regulators discuss knowledge supporting mpox medicine development and approval. The aim is to improve access to mpox treatments.
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Mpox Biology, Outcome, Transmission and Epidemiology
An ongoing clinical trial led by the Institute of Tropical Medicine in Belgium is studying Monkeypox biology, outcomes, transmission, and ep…
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EMA label_change · 2024-09-19EMA recommends extending indication of mpox vaccine to adolescents
EMA recommends extending the mpox vaccine indication to include adolescents, enabling use in this age group during outbreaks.
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Observational, Prospective, Cohort Study of Mpox Infection in Brazil (NETPOX)
This clinical trial update describes an observational, prospective cohort study in Brazil (NETPOX) investigating mpox infection. The study i…