Mitral Regurgitation
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Transcatheter Edge-to-Edge Repair In Moderate and Exertional-Induced Severe MR (TIMER) [EARLY_Phase 1]
Early-phase clinical trial update on transcatheter edge-to-edge repair for functional mitral regurgitation; the study is currently NOT_YET_R…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk [NA]
This trial update announces expansion of the HighLife 28mm trans-septal trans-catheter mitral valve study to include more patients at high s…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery
Clinical trial update indicates ongoing recruitment for a study examining ventricular arrhythmias in patients undergoing mitral valve surger…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: MItral Regurgitation Risk Assessment and CLinical modElling
A clinical trial update indicates a study on mitral regurgitation risk assessment and clinical modeling is currently recruiting at Sun Yat-s…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation [NA]
The document notes the completion of a multicentre study evaluating the MitraClip percutaneous mitral valve repair device in patients with s…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Influence of Original Native Mitral Valve Lesion (Stenosis or Steno-insufficiency vs. Insufficiency) on Post-implant Structural Bioprosthetic Degeneration After Mitral Valve Replacement
A clinical trial entry investigating whether the original native mitral valve lesion (mitral stenosis or mitral regurgitation) influences po…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Additive Prognostic Value of PALS Compared to Bernard's Staging in Patients Undergoing MV Surgery
This clinical trial update evaluates the added prognostic value of Peak Atrial Longitudinal Strain (PALS) versus Bernard's staging for patie…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Beating Heart Mitral Valve Repair With the HARPOON™ System [NA]
Update on the HARPOON beating-heart mitral valve repair trial for mitral regurgitation; the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: A Novel Technique for Percutaneous Mitral Paravalvular Leak Closure: LBBAP Lead Assisted Ventricular Septal Way
Completed clinical trial evaluating a novel percutaneous technique for closing mitral paravalvular leaks using a left bundle branch area pac…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Reduction of Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US) [NA]
Clinical trial update on the SATURN TMVR System (CASSINI-US) for reducing mitral regurgitation; the study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Mitral Valve Annulus Assessment, Multimodality Imaging
A clinical trial evaluating mitral valve annulus assessment using multimodality imaging for mitral regurgitation is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Outcome Registry and Assessment of New Edge-to-Edge Repair
This clinical trial update describes an outcome registry and assessment of a new edge-to-edge mitral valve repair, and the study is currentl…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Early Feasibility Study of Surgical Implantation of a Polymer Prosthetic Mitral and Aortic Valve [NA]
An update on an early feasibility clinical trial evaluating a polymer prosthetic heart valve implanted surgically in the mitral and aortic p…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: The Multi-center Study of Comprehensive Atrial Fibrillation Regurgitation and Recurrent Events Evaluation
A multi-center trial evaluating comprehensive atrial fibrillation-related regurgitation and recurrent events is currently recruiting in pati…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation [NA]
Clinical trial update for the Edwards SAPIEN M3 System Early Feasibility Study in mitral regurgitation; the study is currently active but no…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Use of Phenylephrine for Assessment of Mitral Regurgitation Severity [Phase 1, Phase 2]
This clinical trial update discusses using phenylephrine to assess the severity of mitral regurgitation in Phase 1/2 studies.
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world Practice
A clinical trial update for the Korea VHD Echo Study investigating real-world surveillance of patients with aortic, mitral, and tricuspid va…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Quantification of Mitral Regurgitation Using 4D MRI Flow : Comparison With 2D MRI Flow and Echocardiography Using the Evolution of Left Ventricular Remodeling as a Reference [NA]
Clinical trial update evaluating 4D MRI flow for quantifying mitral regurgitation and comparing it with 2D MRI flow and echocardiography, us…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study
Post-market clinical follow-up study to evaluate Abbott's annuloplasty rings and band in patients with mitral and tricuspid regurgitation; t…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Structural Heart Surgery Assist System for Transcatheter Mitral Valve Edge-to-Edge Repair (TEER). [NA]
A clinical trial for a Structural Heart Surgery Assist System used with transcatheter TEER to treat mitral regurgitation is currently recrui…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: The Prospective Segeberg Registry for Mitral Transcatheter Edge-to-Edge Repair
A prospective registry study evaluating mitral transcatheter edge-to-edge repair for mitral regurgitation, currently recruiting.
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: MiCLASP Post Market Clinical Follow-Up (PMCF) Study
Clinical update on the Edwards Lifesciences MiCLASP PMCF study, which is currently recruiting to assess outcomes in mitral regurgitation and…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: The CardioClip Study [NA]
The CardioClip Study is a Columbia University-sponsored clinical trial that is currently recruiting participants for heart failure with redu…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety
A completed clinical trial assessing the feasibility and safety of early discharge after mitral and tricuspid edge-to-edge repair.
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock [NA]
Ongoing clinical trial evaluating transcatheter mitral valve repair for patients with inotrope-dependent cardiogenic shock, with recruitment…