Migraine
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Gepant treAtments: EffectIveNess and tolERability (GAINER)
University of Florence is conducting the GAINER study evaluating gepant treatments for migraine. The trial is currently recruiting and cover…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Comparative Efficacy of Flunarizine and Propanolol in Pediatric Migraine [NA]
This clinical trial update describes a head-to-head comparison of Flunarizine and Propranolol for pediatric migraine. The study is currently…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment
The University of Florence is recruiting for a study evaluating the effectiveness and tolerability of Rimegepant as a preventive treatment f…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: The Effectiveness of Eptinezumab During a Migraine Attack (the BE-FREE Study)
This clinical trial update describes the BE-FREE study evaluating the effectiveness of eptinezumab when administered during a migraine attac…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Impact of GON PRF on Central Sensitization in Migraine Patients [NA]
A trial is evaluating whether greater occipital nerve pulsed radiofrequency (GON PRF) can impact central sensitization in migraine patients,…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Suppressive Functions of Regulatory T Cells in Migraine [NA]
A clinical trial update describing research on the suppressive functions of regulatory T cells in chronic migraine; the study is not yet rec…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine [Phase 3]
Phase 3 clinical trial update evaluating the efficacy and safety of erenumab in pediatric subjects with chronic migraine; study status indic…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Post-Marketing Study to Assess the Safety and Effectiveness of Oral Atogepant in Korean Adult Participants for the Prevention of Chronic or Episodic Migraine
A post-marketing study to assess the safety and effectiveness of oral atogepant in Korean adults for the prevention of chronic or episodic m…
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FDA approval · 2026-01-18FDA Approved: TOPIRAMATE — Supplemental Application (Glenmark Pharmaceuticals Inc., USA)
FDA approves a supplemental application for TOPIRAMATE from Glenmark Pharmaceuticals Inc., USA.
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA) [NA]
This document is a clinical trial update for a study evaluating injections at myofascial trigger points to treat knee osteoarthritis; the tr…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Intranasal Ketorolac Trial [Phase 2]
A Phase 2 trial evaluating intranasal ketorolac for headache and migraine has been terminated.
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Effects of PFO Closure on Glymphatic Function and Clinical Symptoms in Patients With Migraine [NA]
Ongoing clinical trial evaluating whether closing a patent foramen ovale improves glymphatic function and migraine symptoms.
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Chronic Migraine [NA]
A clinical study is evaluating injections into myofascial trigger points for the treatment of chronic migraine and is currently recruiting a…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD [NA]
Karolinska Institutet is conducting a trial evaluating yoga-based movements for primary headaches, including migraine and cluster headache, …
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Multimodal Brain Function in Migraine Patients With Patent Foramen Ovale
This clinical trial study investigates multimodal brain function in migraine patients with patent foramen ovale. It is currently not yet rec…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: China HeadAche DIsorders RegiStry
A China-based headache disorders registry trial is currently recruiting, covering primary headache disorders and several related conditions …
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: A Study to Learn About the Safety and Effects of Rimegepant to Prevent Migraine in Chinese Subjects. [Phase 3]
Phase 3 study assessing the safety and effects of rimegepant for migraine prevention in Chinese subjects has completed.
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Eptinezumab as Preventive Treatment of Migraine in Adults With Migraine [Phase 3]
Phase 3 study evaluating eptinezumab as a preventive treatment for adults with migraine has completed. The trial was sponsored by H. Lundbec…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Long-Term Extension Study With Eptinezumab as Preventive Treatment in Participants With Migraine in Japan [Phase 3]
This document reports the completion of a long-term extension Phase 3 trial evaluating eptinezumab as a preventive treatment for migraine in…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Consistency of Response With Rimegepant in Acute Treatment of Migraine
Pfizer's ongoing trial on rimegepant for acute migraine reports data on the consistency of patient response; the study status is ACTIVE_NOT_…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli [NA]
Researchers at the University of Minnesota are recruiting participants with Visual Snow Syndrome and migraine, plus healthy controls, to stu…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Amylin-Induced Migraine Attacks Without Aura [NA]
Clinical trial update about a study investigating amylin-induced migraine attacks without aura, with the study status not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Nerivio Efficacy Under High-Frequency Use [Phase 4]
Phase 4 trial update reports on Nerivio's efficacy when used at high frequency for migraine.
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CLINICAL_TRIALS withdrawal · 2026-01-13Clinical Trial Update: A Study to Learn About Zavegepant as a Treatment for Multiple Migraine Attacks in Adult Participants [Phase 3]
Pfizer has withdrawn a Phase 3 trial evaluating Zavegepant for treating multiple migraine attacks in adults. The study was intended to asses…
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FDA approval · 2026-01-12FDA Approved: TOPIRAMATE — Original Application (Camber Pharmaceuticals, Inc.)
This FDA page confirms Camber Pharmaceuticals' original Abbreviated New Drug Application approval for a generic Topiramate product. The appr…