Migraine
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: An Open-label Study to Evaluate Topiramate Therapy in Migraine Patients, and Its Effects on Subject Responsiveness to Migraine Treatment With Triptans [Phase 2]
Phase 2 open-label study evaluating topiramate for migraine and its effects on responsiveness to triptan therapy has completed.
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: A Study of 3 Dosage Strengths of Almotriptan Malate (AXERT®) in the Treatment of Acute Migraine in Adolescents [Phase 3]
Phase 3 clinical trial evaluating three dosage strengths of Almotriptan Malate (AXERT) for acute treatment of migraine in adolescents has co…
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: Potential Impact (Benefit) of Preventative Treatment With Topamax on the Effectiveness of Axert in the Acute Treatment of Migraine [Phase 4]
Phase 4 trial assessing whether preventative topiramate (Topamax) influences the effectiveness of almotriptan (Axert) for acute treatment of…
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: A Study of the Effectiveness and Safety of Almotriptan Versus Placebo in the Treatment of Migraine Headache [Phase 4]
A Phase 4 clinical trial compared almotriptan with placebo for the acute treatment of migraine and assessed effectiveness and safety. The st…
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CLINICAL_TRIALS trial_result · 2011-05-09Clinical Trial Update: Migraine Study in Adolescent Patients [Phase 3]
Phase 3 migraine trial in adolescent patients completed; results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-02-01Clinical Trial Update: The Effectiveness and Safety of Topiramate on Prevention of Chronic Migraine [Phase 3]
This report covers a Phase 3 trial evaluating topiramate for prevention of chronic migraine. It summarizes the effectiveness and safety find…
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CLINICAL_TRIALS trial_result · 2011-01-27Clinical Trial Update: A Study of Rizatriptan for the Treatment of Acute Migraine in Patients on Topiramate for Migraine Prophylaxis [Phase 3]
A Phase 3 trial evaluated rizatriptan for acute treatment of migraine in patients already on topiramate for migraine prevention; the study c…
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: "Completeness of Response" Following Treatment With Treximet™ for Migraine [Phase 4]
Phase 4 clinical trial update on completeness of response after Treximet treatment for migraine; results have been posted.
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CLINICAL_TRIALS trial_result · 2011-01-20Clinical Trial Update: A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine (0462-087) [Phase 3]
A Phase 3 trial evaluating Rizatriptan for the treatment of acute migraine has completed and its results have been posted.
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CLINICAL_TRIALS trial_result · 2011-01-14Clinical Trial Update: Zolmitriptan Nasal Spray Versus Eletriptan in the Acute Treatment of Migraine [NA]
This completed randomized trial compared Zolmitriptan nasal spray with Eletriptan for the acute treatment of migraine.
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CLINICAL_TRIALS trial_result · 2011-01-11Clinical Trial Update: EP4-receptor Antagonism and Prostaglandin E2 (PGE2) in a Human Headache Model [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating an EP4 receptor antagonist with Prostaglandin E2 (PGE2) in a human headache model has completed.
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CLINICAL_TRIALS trial_result · 2011-01-04Clinical Trial Update: Bioequivalence Study of Sumatriptan Succinate Tablets 100 mg in Fed Conditions [Phase 1]
A Phase 1 bioequivalence study of Sumatriptan Succinate tablets 100 mg under fed conditions in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2010-12-29Clinical Trial Update: TREXIMET® Versus Butalbital-containing Combination Medications for the Acute Treatment of Migraine in Adults [Phase 3]
Phase 3 trial comparing TREXIMET (sumatriptan/acetaminophen) with butalbital-containing combination medications for acute treatment of migra…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: A Study Using Botulinum Toxin Type A as Headache Prophylaxis for Migraine Patients With Frequent Headaches [Phase 3]
Phase 3 study evaluating botulinum toxin type A as a preventive treatment for patients with frequent migraines; results posted.
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CLINICAL_TRIALS trial_result · 2010-12-06Clinical Trial Update: Safety and Efficacy Study of MK0974 in the Acute Migraine (0974-016) [Phase 3]
Phase 3 safety and efficacy study of MK0974 (telcagepant) for acute migraine has completed, with results posted on 2010-12-06.
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CLINICAL_TRIALS trial_result · 2010-12-01Clinical Trial Update: Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives. [Phase 4]
Phase 4 clinical trial update evaluating whether adding back estrogen during the hormone-free interval reduces menstrual migraines in women …
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CLINICAL_TRIALS trial_result · 2010-11-22Clinical Trial Update: MK3207 for Treatment of Acute Migraines (3207-005) [Phase 2]
Merck's MK-3207 Phase 2 trial for acute treatment of migraines has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2010-11-19Clinical Trial Update: A Study of the Efficacy and Safety of Two Doses of Topiramate Compared to Placebo and Propranolol in the Prevention of Migraine [Phase 3]
This Phase 3 trial comparing two doses of topiramate to placebo and propranolol for migraine prevention has completed.
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CLINICAL_TRIALS trial_result · 2010-11-19Clinical Trial Update: A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine [Phase 3]
A completed Phase 3 study evaluating the efficacy and safety of Topiramate for the prevention of migraine. The trial was sponsored by Johnso…
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CLINICAL_TRIALS trial_result · 2010-11-18Clinical Trial Update: A Research Study To Evaluate If Frovatriptan Is Safe And Effective In Preventing Migraine Headache After Fasting [NA]
This completed trial evaluated whether frovatriptan can safely and effectively prevent migraine headaches after fasting.
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CLINICAL_TRIALS trial_result · 2010-11-17Clinical Trial Update: A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine [Phase 3]
Phase 3 trial evaluating topiramate for migraine prevention has completed, assessing its efficacy and safety.
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CLINICAL_TRIALS trial_result · 2010-11-03Clinical Trial Update: Determine Central 5-HT1B Receptor Occupancy of ZOMIG® Rapimelt (Zolmitriptan) in Healthy Male Volunteers [Phase 1]
Phase 1 study assessing central occupancy of the 5-HT1B receptor by ZOMIG Rapimelt (zolmitriptan) in healthy male volunteers to inform pharm…
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CLINICAL_TRIALS trial_result · 2010-09-15Clinical Trial Update: A Dose-Finding Study of MK0974 in Acute Migraine (MK0974-004) [Phase 2]
Phase 2 dose-finding trial of MK0974 (telcagepant) for acute migraine completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2010-09-06Clinical Trial Update: Long-Term Safety of Treximet (Sumatriptan/Naproxen Sodium) for Migraine in Adolescents [Phase 3]
A Phase 3 study evaluating the long-term safety of Treximet (sumatriptan/naproxen) in adolescents with migraine has completed; results were …
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CLINICAL_TRIALS trial_result · 2010-07-23Clinical Trial Update: MK0462 5 mg, Sumatriptan 50 mg, and Placebo Comparison Study (0462-029) [Phase 3]
Phase 3 trial comparing MK0462 5 mg, Sumatriptan 50 mg, and placebo for migraine headache has completed with results posted.