Methicillin-resistant Staphylococcus Aureus Infection
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FDA approval · 2019-02-15FDA Approved: TYZAVAN — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved TYZAVAN (vancomycin) from Hikma Pharmaceuticals USA Inc. under an Original Application (NDA211962). This marks the brand’s offi…
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Combination Antibiotic Therapy for Methicillin Resistant Staphylococcus Aureus Infection [Phase 3]
A Phase 3 clinical trial evaluating a combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection was terminate…
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Individualized vs. Household MRSA Decolonization [NA]
A completed clinical trial comparing individualized MRSA decolonization with household decolonization; results were posted in 2018.
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CLINICAL_TRIALS withdrawal · 2018-09-11Clinical Trial Update: Efficacy Study of Altabax to Clear Methicillin-resistant Staphylococcus Aureus (MRSA) Nasal Colonization [Phase 4]
A Phase 4 trial evaluating Altabax for MRSA nasal colonization was withdrawn.
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Comparison of Standard Isolation With Targeted Isolation for Preventing Nosocomial Transmission of MRSA and VRE [NA]
A completed clinical trial comparing standard isolation with targeted isolation to prevent hospital-acquired transmission of MRSA and VRE.
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CLINICAL_TRIALS trial_result · 2018-03-20Clinical Trial Update: Stop Community MRSA Colonization Among Patients [Phase 4]
A completed Phase 4 clinical trial led by Johns Hopkins University evaluated strategies to prevent community colonization by Methicillin-res…
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Efficacy Study of Vitamin D Supplementation to Meticillin Resistant Staphylococcus Aureus (MRSA) Carriers [Phase 2]
Phase 2 trial evaluating vitamin D supplementation to MRSA carriers; completed.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: MESS-study MRSA Eradication Study Skåne [NA]
The MESS-study MRSA Eradication Study in Skåne has completed. It investigated eradication strategies for throat carriers of MRSA.
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Patient-Centered Comparative Effectiveness Research (CER) Study of Home-based Interventions to Prevent CA-MRSA Infection Recurrence [Phase 4]
A Phase 4 patient-centered comparative effectiveness trial is examining home-based interventions to prevent recurrence of community-associat…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Prospective Evaluation of a Vancomycin Nomogram With a Continuous Infusion of Vancomycin for Surgical ICU Patients [Phase 4]
Phase 4 clinical trial evaluating a vancomycin nomogram with continuous infusion in surgical ICU patients was terminated; results were poste…
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CLINICAL_TRIALS withdrawal · 2017-03-23Clinical Trial Update: Comparison of Decolonization of Methicillin-resistant Staphylococcus Aureus (MRSA) Using Theraworx [NA]
A clinical trial comparing decolonization of MRSA using Theraworx has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Gown and Glove Use to Prevent the Spread of Infection in VA Community Living Centers
A clinical trial update on gown and glove use to prevent the spread of MRSA in VA community living centers; study completed with results pos…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: CA-MRSA Infection in China: Epidemiology, Molecular Characteristics, Treatment, and Outcome
A clinical trial update from China on community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection, covering epidemi…
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CLINICAL_TRIALS research · 2016-06-29Clinical Trial Update: Epidemiology and Prevention of Methicillin Resistant Staphylococcus Aureus (MRSA) Transmission in the Community [NA]
A completed clinical trial on MRSA transmission epidemiology and prevention in the community.
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CLINICAL_TRIALS withdrawal · 2016-05-20Clinical Trial Update: The Efficacy of SinoFresh Nasal and Sinus Care Nasal Spray in Eliminating MRSA From the Nasal Cavity [NA]
The clinical trial evaluating SinoFresh Nasal and Sinus Care Nasal Spray for eliminating Methicillin-resistant Staphylococcus aureus from th…
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CLINICAL_TRIALS withdrawal · 2016-03-01Clinical Trial Update: Hospital Acquired and Community Acquired MRSA in GI Lab
The Indiana University-sponsored trial addressing Hospital Acquired MRSA and Community Acquired MRSA has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Randomized Controlled Trial of Antibiotics in the Management of Children With Community-Acquired Abscess [NA]
A randomized controlled trial evaluating antibiotics for children with community-acquired soft tissue abscesses, including MRSA infections, …
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: A Pilot Trial to Determine the Efficacy of Lactobacillus Rhamnosus for Reducing Colonization by Methicillin-resistant Staphylococcus Aureus (MRSA) (PROSE) [Phase 2]
Phase 2 pilot trial evaluating whether Lactobacillus rhamnosus can reduce colonization by MRSA; the study is completed.
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections [Phase 3]
Phase 3 trial comparing cotrimoxazole to vancomycin for invasive MRSA infections has completed. It evaluated outcomes in meningitis, sepsis,…
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Comparison of Bacterial Contamination Rates Between Isolation and Non-isolation Rooms
A completed clinical trial compared bacterial contamination rates between isolation rooms and non-isolation rooms in the context of methicil…
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CLINICAL_TRIALS research · 2015-05-13Clinical Trial Update: Pharmacokinetics/ Pharmacodynamics (PK/PD) Study of Vancomycin [Phase 4]
A Phase 4 pharmacokinetics/pharmacodynamics study of vancomycin is described, sponsored by Zhejiang University, examining its PK/PD in blood…
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CLINICAL_TRIALS trial_result · 2014-12-18Clinical Trial Update: MRSA in a Trauma Population: Does Decolonization Prevent Infection? [NA]
This clinical trial update reports on whether decolonization strategies can prevent MRSA infections in trauma patients. The study (NCT018204…
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Methicillin-resistant Staphylococcus Aureus (MRSA) Skin and Soft Tissue Infection (SSTI) Prevention in Military Trainees [NA]
Clinical trial update on MRSA SSTI prevention in military trainees; study completed with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-05Clinical Trial Update: Randomized Clinical Trial to Compare a Regimen of Trimethoprim-sulfamethoxazole Plus Rifampicin With a Regimen of Linezolid in the Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection [Phase 4]
A Phase 4 randomized trial comparing trimethoprim-sulfamethoxazole plus rifampicin to linezolid for MRSA infection has completed.
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CLINICAL_TRIALS trial_result · 2014-07-10Clinical Trial Update: Evaluation of Patients With Methicillin-Resistant Staphylococcus Aureus Hospital-Acquired Pneumonia Treated With Linezolid or Vancomycin
A completed clinical trial comparing linezolid versus vancomycin for MRSA hospital-acquired pneumonia, with results posted in 2014.