Castration-resistant Prostate Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours [Phase 1, Phase 2]
Cancer Research UK reported an ongoing Phase 1/2a trial of HMBD-001 in HER3-positive solid tumors; the study is currently Active Not Recruit…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Study to Evaluate CCS1477 in Advanced Tumours [Phase 1, Phase 2]
A Phase 1/2 study of CCS1477 has completed, evaluating it in metastatic castration-resistant prostate cancer and metastatic breast cancer, w…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors [Phase 1]
Phase 1, first-in-human dose-finding and expansion study of XmAb808 in combination with pembrolizumab in advanced solid tumors; the trial ha…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Study of TY-302 Capsules Combined With Abiraterone in Patients With Metastatic Castration-resistant Prostate Cancer（mCRPC） [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TY-302 in combination with Abiraterone for metastatic castration-resistant prostate cancer; the study …
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Study of TYK-00540 Combined With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer（mCRPC） [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TYK-00540 in combination with enzalutamide for metastatic castration-resistant prostate cancer (mCRPC)…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Trial of LAVA-1207 in Patients With Therapy Refractory Metastatic Castration Resistant Prostate Cancer (mCRPC) Resistant Prostate Cancer [Phase 1]
A Phase 1 study of LAVA-1207 in patients with therapy-refractory metastatic castration-resistant prostate cancer has been terminated.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: SPECT/CT Imaging for Dosimetry in 177Lu-PSMA-617 (Pluvicto) Therapy
This entry notes a recruiting clinical trial evaluating SPECT/CT imaging-based dosimetry to optimize Lutetium-177 PSMA-617 therapy for metas…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: MGC018 With or Without MGA012 in Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports results from the combination of MGC018 with or without MGA012 (pembrolizumab) in advanced solid tumors. T…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: 177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer [Phase 3]
A Phase 3 clinical trial evaluating 177Lu-PSMA-I&T for metastatic castration-resistant prostate cancer is currently active but not recruitin…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: A Study of [177Lu] Lu-PSMA-XT Injection in Patients With Metastatic Prostate Cancer [Phase 1]
This entry details a Phase 1 clinical trial evaluating [177Lu] Lu-PSMA-XT Injection in patients with metastatic castration-resistant prostat…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Efficacy and Safety of Disitamab Vedotin Plus Abiraterone for Metastatic Castration-Resistant Prostate Cancer：a Phase II Study [Phase 2]
Phase II clinical trial evaluating the combination of disitamab vedotin and abiraterone for metastatic castration-resistant prostate cancer;…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Phase Ib Trial of 177Lu-PSMA-I&T Therapy in Combination With Olaparib and Pembrolizumab in Patients With Metastatic Castration Resistant Prostate Cancer [Phase 1]
Phase Ib trial evaluating 177Lu-PSMA-I&T in combination with olaparib and pembrolizumab for metastatic castration-resistant prostate cancer;…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: Trial of ARV-110 and Abiraterone in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC) [Phase 1]
Phase 1 trial evaluating ARV-110 in combination with Abiraterone for Metastatic Castration-Resistant Prostate Cancer has completed.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Prostate Cancer Postoperative Stereotactic Body Radiotherapy With Adaptive Technology for Minimizing Toxicity
This clinical trial is evaluating postoperative stereotactic body radiotherapy with adaptive technology to minimize toxicity in prostate can…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Phase 1 Trial of SYNC-T - Immunotherapy for Advanced/Metastatic Castration-Resistant Prostate Cancer [Phase 1]
A Phase 1 clinical trial evaluating SYNC-T immunotherapy for metastatic castration-resistant prostate cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1/2 study evaluating an adenosine receptor antagonist in combination therapy fo…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer [Phase 1, Phase 2]
Clinical trial update on safety and pharmacokinetics of ODM-208 in patients with metastatic castration-resistant prostate cancer (Phase 1/2)…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer [Phase 2]
This is a Phase 2 clinical trial evaluating ZEN-3694 in combination with enzalutamide and pembrolizumab for metastatic castration-resistant …
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Imaging of Solid Tumors Using 18F-TRX [Phase 1]
A Phase 1 study is evaluating imaging of solid tumors with the radiotracer 18F-TRX. The trial is currently recruiting and includes prostate …
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: XmAb®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer [Phase 2]
Clinical trial update noting the completion of a Phase 2 study of XmAb20717 (Vudalimab), as monotherapy or in combination with chemotherapy …
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Gallium Ga 68-DOTATATE PET/CT in Diagnosing Patients With Metastatic Castration Resistant Prostate Cancer [Phase 2]
Phase 2 trial evaluating Ga-68 DOTATATE PET/CT for diagnosing metastatic castration-resistant prostate cancer has completed, with results po…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors [Phase 1]
A Phase 1 trial of INCB106385, alone or with immunotherapy, in advanced solid tumors has completed. The study includes multiple indications …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global) [Phase 3]
This update describes a phase 3 trial evaluating 177Lu-TLX591 in combination with standard of care versus standard of care alone for metasta…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases
A completed clinical trial investigating the use of Xofigo (radium-223 dichloride) in metastatic castration-resistant prostate cancer with b…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: 68Ga-PSMA-11 PET/CT Screening Prior to 177Lu-PSMA-617 Therapy for Patients With Metastatic Castrate Resistant Prostate Cancer [Phase 3]
Phase 3 trial evaluating 68Ga-PSMA-11 PET/CT screening before Lu-177-PSMA-617 therapy in metastatic castration-resistant prostate cancer has…