Castration-resistant Prostate Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC) [Phase 2]
Phase 2 clinical trial evaluating dosimetry, randomized dose optimization, dose escalation, and efficacy of Ac-225 Rosopatamab Tetraxetan in…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: A Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of [225Ac]Ac-PSMA-XT Injection in Patients With Metastatic Castration-resistant Prostate Cancer [Phase 1]
This entry describes a Phase 1 clinical study evaluating the safety, tolerability, and preliminary efficacy of [225Ac]Ac-PSMA-XT Injection i…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA [Phase 2]
Phase 2 clinical trial evaluating treatment optimization for metastatic castration-resistant prostate cancer using analysis of circulating t…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update on cabozantinib alone or with atezolizumab for locally advanced or metastatic solid tumors; the study lists mu…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Liquid Biopsy Under PSMA Radioligand Therapy
A clinical trial conducted by Würzburg University Hospital is investigating the use of liquid biopsy in patients with metastatic castration-…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Combining Ipilimumab With Abiraterone Acetate Plus Prednisone in Chemotherapy and Immunotherapy-naïve Patients With Progressive Metastatic Castration-resistant Prostate Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating the combination of ipilimumab with abiraterone acetate plus prednisone in …
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Prospective Clinical Trial of 225Ac-LNC1011 in the Treatment of Metastatic Castration-Resistant Prostate Cancer [Phase 1, Phase 2]
A prospective Phase 1/2 clinical trial is evaluating 225Ac-LNC1011 for metastatic castration-resistant prostate cancer and is currently recr…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Study of TY-302 Capsules Combined With Abiraterone in Patients With Metastatic Castration-resistant Prostate Cancer（mCRPC） [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TY-302 in combination with Abiraterone for metastatic castration-resistant prostate cancer; the study …
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Study of TYK-00540 Combined With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer（mCRPC） [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TYK-00540 in combination with enzalutamide for metastatic castration-resistant prostate cancer (mCRPC)…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: SPECT/CT Imaging for Dosimetry in 177Lu-PSMA-617 (Pluvicto) Therapy
This entry notes a recruiting clinical trial evaluating SPECT/CT imaging-based dosimetry to optimize Lutetium-177 PSMA-617 therapy for metas…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: 177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer [Phase 3]
A Phase 3 clinical trial evaluating 177Lu-PSMA-I&T for metastatic castration-resistant prostate cancer is currently active but not recruitin…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: A Study of [177Lu] Lu-PSMA-XT Injection in Patients With Metastatic Prostate Cancer [Phase 1]
This entry details a Phase 1 clinical trial evaluating [177Lu] Lu-PSMA-XT Injection in patients with metastatic castration-resistant prostat…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Efficacy and Safety of Disitamab Vedotin Plus Abiraterone for Metastatic Castration-Resistant Prostate Cancer：a Phase II Study [Phase 2]
Phase II clinical trial evaluating the combination of disitamab vedotin and abiraterone for metastatic castration-resistant prostate cancer;…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Phase Ib Trial of 177Lu-PSMA-I&T Therapy in Combination With Olaparib and Pembrolizumab in Patients With Metastatic Castration Resistant Prostate Cancer [Phase 1]
Phase Ib trial evaluating 177Lu-PSMA-I&T in combination with olaparib and pembrolizumab for metastatic castration-resistant prostate cancer;…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Prostate Cancer Postoperative Stereotactic Body Radiotherapy With Adaptive Technology for Minimizing Toxicity
This clinical trial is evaluating postoperative stereotactic body radiotherapy with adaptive technology to minimize toxicity in prostate can…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Phase 1 Trial of SYNC-T - Immunotherapy for Advanced/Metastatic Castration-Resistant Prostate Cancer [Phase 1]
A Phase 1 clinical trial evaluating SYNC-T immunotherapy for metastatic castration-resistant prostate cancer has completed.
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer [Phase 1, Phase 2]
Clinical trial update on safety and pharmacokinetics of ODM-208 in patients with metastatic castration-resistant prostate cancer (Phase 1/2)…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer [Phase 2]
This is a Phase 2 clinical trial evaluating ZEN-3694 in combination with enzalutamide and pembrolizumab for metastatic castration-resistant …
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Imaging of Solid Tumors Using 18F-TRX [Phase 1]
A Phase 1 study is evaluating imaging of solid tumors with the radiotracer 18F-TRX. The trial is currently recruiting and includes prostate …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global) [Phase 3]
This update describes a phase 3 trial evaluating 177Lu-TLX591 in combination with standard of care versus standard of care alone for metasta…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: The Radium-select Study [NA]
The Radium-select study, sponsored by The Netherlands Cancer Institute, is currently recruiting to investigate treatment options for metasta…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer [Phase 3]
Phase 3 trial update for acetylsalicylic acid (aspirin) and atorvastatin in patients with castration-resistant prostate cancer; recruitment …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: The Impact of Metastatic Directed Radiotherapy (MDRT) on Oligoprogressive Castration Resistant Prostate Cancer (CRPC) [Phase 2]
A Phase 2 clinical trial update evaluating metastasis-directed radiotherapy for oligoprogressive metastatic castration-resistant prostate ca…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Experience of 177Lu-PSMA-617-administration on Port Reservoir (TIVAP)
This clinical trial update describes experiences administering Lutetium-177-PSMA-617 via a port reservoir (TIVAP). The study is currently re…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: HTL0039732 in Participants With Advanced Solid Tumours [Phase 1, Phase 2]
HTL0039732 is being evaluated in a Phase 1/2 study for multiple advanced solid tumours and is currently recruiting.