Castration-resistant Prostate Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer [Phase 2]
This clinical trial update describes a Phase 2 study evaluating the combination of apalutamide with carotuximab for metastatic castration-re…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Development and Prospective Validation of a Pathology-Based Artificial Intelligence Model for Predicting the Time to Castration Resistance of Prostate Cancer
Development and prospective validation of a pathology-based AI model to predict the time to castration resistance in prostate cancer.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan [Phase 4]
Phase 4 clinical trial pilot evaluating 18F-DCFPyL-PSMA PET imaging in men with metastatic castration-resistant prostate cancer who are rece…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Study With [225Ac]Ac-FL-020 in mCRPC Participants [Phase 1]
A Phase 1 clinical trial update for [225Ac]Ac-FL-020 in metastatic castration-resistant prostate cancer. The study (NCT06492122) is currentl…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer [Phase 3]
A Phase 3 clinical trial comparing BMS-986365 to investigator's choice therapy in metastatic castration-resistant prostate cancer, currently…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resistant Prostate Cancer [Phase 2]
A Phase 2 clinical trial evaluating the efficacy of combining hypoxia-targeting therapy with an ARSI after first-line ARSI in castration-res…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer [Phase 2]
A Phase 2 clinical trial evaluating the combination of vorinostat and Lutetium-177 PSMA-617 for PSMA-low metastatic castration-resistant pro…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: GZ17-6.02 in Advanced CRPC After Progression on Anti-Androgen Therapy [Phase 1]
A Phase 1 clinical trial (GZ17-6.02) for advanced castration-resistant prostate cancer is currently recruiting after progression on anti-and…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer [Phase 3]
A Phase III clinical trial evaluating BNT324 versus docetaxel in metastatic castration-resistant prostate cancer is listed as not yet recrui…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer [Phase 2]
A Phase 2 clinical trial evaluating cabozantinib in combination with nivolumab for metastatic castration-resistant prostate cancer is curren…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study of Allogeneic Anti-PSMA CAR-NK Cell for Metastatic Castration-Resistant Prostate Cancer [EARLY_Phase 1]
Early-phase clinical trial evaluating allogeneic anti-PSMA CAR-NK cells for metastatic castration-resistant prostate cancer is currently rec…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: An Exploratory Clinical Study Evaluating the Safety and Efficacy of Allogeneic CAR-NK Cell Therapy for Metastatic Castration-resistant Prostate Cancer (mCRPC) [EARLY_Phase 1]
This document describes an early-phase (Phase 1) exploratory clinical study evaluating the safety and potential efficacy of an allogeneic CA…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body [Phase 3]
This ClinicalTrials.gov entry outlines a Phase 3 trial evaluating whether adding carboplatin chemotherapy to cabazitaxel improves outcomes c…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01) [Phase 1]
Phase 1 study ENGAGER-PSMA-01 evaluating JANX007 in metastatic castration-resistant prostate cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies [Phase 1]
Phase 1 study update for DSB2455 assessing safety, tolerability, and activity in advanced HRD-associated cancers, including breast cancer, o…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Adoptive Transfer of Autologous T Cells Targeted to Prostate Specific Membrane Antigen (PSMA) for the Treatment of Castrate Metastatic Prostate Cancer (CMPC) [Phase 1]
Phase 1 clinical trial evaluating autologous T cells engineered to target PSMA for men with metastatic castration-resistant prostate cancer.
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Trial of HRS-5041-103 to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of HRS-5041 in Subjects With Metastatic Castration-resistant Prostate Cancer [Phase 1]
ClinicalTrials.gov entry indicates that HRS-5041-103 is a Phase 1 study assessing safety, tolerability, pharmacokinetics and efficacy in met…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Phase I Trial of A-CAR032 in Participants With mCRPC [Phase 1]
The document details a Phase I clinical trial of A-CAR032 for metastatic castration-resistant prostate cancer, with the study currently recr…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update on the Phase 1/Phase 2 safety and efficacy study of NUV-1511 in adults with advanced solid tumors, including HER2-nega…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study [Phase 2]
A Phase 2 clinical trial (SPECTRA) is evaluating whether supraphysiological androgen can enhance treatment activity in metastatic castration…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer [Phase 2]
Phase 2 trial evaluating a combination of difluoromethylornithine, high-dose testosterone, and enzalutamide for metastatic castration-resist…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors [Phase 1, Phase 2]
A first-in-human Phase 1/2 trial of JAB-8263 in adults with advanced tumors is currently recruiting across multiple cancer types including l…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations [Phase 2]
A Phase 2 clinical trial update for CJNJ-67652000 in combination with prednisone to treat metastatic castration-resistant prostate cancer, i…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Study of Re-treatment With [177Lu]Lu-PSMA in Men With Metastatic Castration Resistance Prostate Cancer [Phase 2]
Phase 2 trial evaluating re-treatment with Lutetium-177–PSMA in men with metastatic castration-resistant prostate cancer; the study is curre…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Phase I Study of Docetaxel and 177-Lutetium-PSMA-I&T in First-Line Treatment for Patients With Metastatic Castration-Resistant Prostate Adenocarcinoma [Phase 1]
Phase I clinical trial evaluating the combination of Docetaxel and Lutetium-177 PSMA-I&T as first-line treatment for metastatic castration-r…